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Advair Hfa Inhaler — prescription drug image

Advair Hfa

Advair HFA 12GM of 115-21MCG/ACT

Prescriptions & Refills
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What is Advair Hfa?

Advair HFA (fluticasone propionate and salmeterol) is a combination inhaler used in the management of asthma and chronic obstructive pulmonary disease (COPD). It contains fluticasone, a corticosteroid that reduces inflammation, and salmeterol, a long-acting beta-agonist that relaxes airway muscles to enhance breathing. Advair HFA is typically prescribed for patients who need regular treatment to control their respiratory symptoms and is administered through a metered-dose inhaler.

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What is Advair Hfa ?

Advair HFA (fluticasone propionate and salmeterol) is a combination inhaler used in the management of asthma and chronic obstructive pulmonary disease (COPD). It contains fluticasone, a corticosteroid that reduces inflammation, and salmeterol, a long-acting beta-agonist that relaxes airway muscles to enhance breathing. Advair HFA is typically prescribed for patients who need regular treatment to control their respiratory symptoms and is administered through a metered-dose inhaler.
  • Eye pain or trouble seeing
  • Tremors, nervousness, or shaking
  • Unusual tiredness or weakness
  • Fast, pounding, or uneven heartbeat
  • Worsening of breathing problems
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Changes in skin color, dark freckles, easy bruising, muscle weakness, round or puffy face
  • Chest pain, trouble breathing
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting
  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, cataracts, diabetes, glaucoma, heart disease, high blood pressure, heart rhythm problems, thyroid problems, seizures, or osteoporosis. Tell your doctor about any immune system problems or infections, including herpes simplex in your eye, tuberculosis, or parasites. Tell your doctor if you have been exposed to chickenpox or measles.
  • This medicine may cause the following problems:Increased risk of asthma-related hospital stays, intubations, and deathIncreased trouble breathing right after use (paradoxical bronchospasm)Increased risk of pneumonia in people who have COPDIncreased risk of infection, including fungus infection in the mouth (thrush)Low bone mineral density, which may lead to osteoporosisCataracts, glaucoma, or other vision problemsSlow growth in childrenAdrenal gland problems
  • This medicine will not stop an asthma attack that has already started. You should have another medicine to use in case of an acute asthma attack or COPD flare-up. Tell your doctor right away if your condition gets worse or you need to use your other medicine more often than usual.
  • Inhalation routeIf any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
  • Tell any doctor or dentist who treats you that you are using this medicine.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is the difference between Advair HFA and Advair Diskus?
Advair HFA is a metered-dose aerosol inhaler you spray, while Advair Diskus is a dry-powder inhaler you inhale by breathing in. They deliver the same two active ingredients but are different devices, and Advair Diskus is approved for a broader age range and also has a COPD indication that Advair HFA does not.
Is there a generic version of Advair HFA?
Not currently. There is no FDA-approved generic marketed for the Advair HFA aerosol inhaler itself, though a generic exists for the separate Advair Diskus powder inhaler.
Is Advair HFA a rescue inhaler?
No. Advair HFA is a twice-daily maintenance inhaler for ongoing asthma control. It is not intended to relieve a sudden asthma attack, so you should keep a separate rescue inhaler for that purpose.
Who can use Advair HFA?
Advair HFA is approved for asthma maintenance treatment in patients 12 years of age and older.
Can I use a manufacturer copay card and an Rx.com coupon together?
No, you'd choose one or the other for a given fill. The manufacturer card generally requires commercial insurance, while an Rx.com cash coupon can be used regardless of insurance status, including if you're uninsured or on Medicare.
How much does Advair Hfa cost without insurance?
The price of Advair Hfa without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 52% off retail prices with a free Rx.com coupon.
What are the common side effects of Advair Hfa?
Common side effects of Advair Hfa may include: Eye pain or trouble seeing, Tremors, nervousness, or shaking, Unusual tiredness or weakness, Fast, pounding, or uneven heartbeat, Worsening of breathing problems. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Advair Hfa?
Generic versions may be available for Advair Hfa. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Advair Hfa on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Advair Hfa?
The cheapest pharmacy for Advair Hfa depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Advair Hfa near you.

Advair Hfa Coupons & Prices

Advair HFA 12GM of 115-21MCG/ACT

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Advair Hfa Inhaler — prescription drug image
Prescription
Advair Hfa 12gm of 115-21mcg/act (120 inhalations) (1)
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Advair Hfa prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
8gm of 115-21mcg/act (60 inhalations) · Inhaler 12 $281.64 $234.54
8gm of 230-21mcg/act (60 inhalations) · Inhaler 12 $460.35 $380.19
8gm of 45-21mcg/act (60 inhalations) · Inhaler 12 $393.92 $252.20
8gm of 115-21mcg/act · Inhaler 8 $234.07 $219.03
12gm of 115-21mcg/act (120 inhalations) · Inhaler 12 $321.92 $316.90
12gm of 230-21mcg/act (120 inhalations) · Inhaler 12 $687.99 $435.04
12gm of 45-21mcg/act (120 inhalations) · Inhaler 12 $423.99 $250.28
12gm of 115-21mcg/act · Inhaler 12 $409.95 $316.90

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Advair HFA is a brand-name inhaler that combines fluticasone propionate and salmeterol to control asthma. It's the metered-dose aerosol inhaler formulation (distinct from the Advair Diskus powder inhaler), and there is no marketed generic substitute for this exact HFA aerosol product, so many patients look for an Advair HFA coupon to lower the cash price. Enter your ZIP above to see today's price at pharmacies near you.

What is Advair HFA and how does it work?

Advair HFA combines an inhaled corticosteroid (fluticasone propionate) with a long-acting beta2-adrenergic agonist (salmeterol) in a single metered-dose aerosol inhaler. It's FDA-approved for the maintenance treatment of asthma in patients 12 years of age and older who aren't adequately controlled on a long-term asthma-control medication, or whose disease warrants starting both an inhaled corticosteroid and a LABA together. Advair HFA is not approved for COPD and is not intended for relief of a sudden asthma attack — it's a twice-daily maintenance inhaler, not a rescue inhaler.

Manufacturer savings card vs. an Rx.com cash coupon

GSK, the maker of Advair HFA, offers an official manufacturer savings program for eligible patients; terms, eligibility, and savings amounts vary and are set by GSK, so check the manufacturer's official site directly. Like most copay cards, it's generally limited to people with commercial insurance and typically can't be used with Medicare, Medicaid, or if you're uninsured. An Rx.com cash coupon works differently: it's not tied to insurance status, so it's an option if you're uninsured, on Medicare, or if your copay card is declined at the pharmacy counter.

Is there a generic for Advair HFA?

No FDA-approved generic is currently marketed for the Advair HFA aerosol inhaler specifically. A separate product, the Advair Diskus dry-powder inhaler, does have marketed generic versions (such as Wixela Inhub) — but that's a different device and formulation from the HFA aerosol, so it isn't a direct substitute if your prescription is written for Advair HFA. Ask your doctor or pharmacist whether switching inhaler devices makes sense for you.

Safety information

Medicines like Advair HFA that contain a long-acting beta agonist (LABA) can increase the risk of asthma-related hospitalization or death when the LABA is used alone; Advair HFA pairs the LABA with an inhaled corticosteroid, which is intended to reduce this risk compared with a LABA by itself. Advair HFA is not for treating sudden breathing problems — keep a rescue inhaler on hand for that. This is general information, not medical advice; talk to your doctor or pharmacist about whether Advair HFA is right for you.

Sources & accuracy

This Advair Hfa information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Advair Hfa on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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