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Combipatch

CombiPatch

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What is Combipatch?

CombiPatch (estradiol/norethindrone acetate) is a prescription hormone replacement therapy (HRT) patch used to treat moderate to severe menopause symptoms, including hot flashes and night sweats. It combines estrogen and progestin to help relieve symptoms while protecting the uterine lining in women who have not had a hysterectomy.

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  • Unusual or unexpected vaginal bleeding or heavy bleeding
  • Swelling in your hands, ankles, or feet
  • Sudden or severe stomach pain, nausea, or vomiting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting
  • Chest pain, trouble breathing, or coughing up blood
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Vision changes, vision loss, double vision, migraine headache
  • Pregnancy after menopause is not likely, but if you think you could be pregnant, tell your doctor. This medicine could harm an unborn baby.
  • Tell your doctor if you are breastfeeding or if you have kidney disease, heart disease, asthma, diabetes, endometriosis, epilepsy, migraine headaches, porphyria, lupus, an underactive thyroid, high blood pressure, or high cholesterol. Tell your doctor if you have ever had liver problems caused by pregnancy or estrogen, or if you smoke.
  • Do not use this medicine if you had a hysterectomy.
  • This medicine may cause the following problems:Increased risk of heart attack, stroke, or blood clotsIncreased risk of endometrial cancer, breast cancer, or uterine cancerIncreased risk of dementia, especially in women 65 years of age and olderGallbladder disease
  • You may need to stop using this medicine for a few weeks before and after you have surgery or if you need to be on bedrest, because of the risk of blood clots.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. You should have regular pelvic exams, breast exams, and mammograms as directed by your doctor.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Vision changes, vision loss, double vision, migraine headache
How much does CombiPatch cost without insurance?
The price of CombiPatch without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of CombiPatch?
Common side effects of CombiPatch may include: Unusual or unexpected vaginal bleeding or heavy bleeding, Swelling in your hands, ankles, or feet, Sudden or severe stomach pain, nausea, or vomiting, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of CombiPatch?
Generic versions may be available for CombiPatch. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search CombiPatch on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for CombiPatch?
The cheapest pharmacy for CombiPatch depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for CombiPatch near you.

Combipatch Coupons & Prices

CombiPatch

What is Combipatch ?

CombiPatch (estradiol/norethindrone acetate) is a prescription hormone replacement therapy (HRT) patch used to treat moderate to severe menopause symptoms, including hot flashes and night sweats. It combines estrogen and progestin to help relieve symptoms while protecting the uterine lining in women who have not had a hysterectomy.

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Combipatch Box — prescription drug image
Prescription
Combipatch 1 box (8 twice weekly patches), 0.05-0.14mg/day (1)
your area ·

CombiPatch (estradiol and norethindrone acetate) is a prescription hormone replacement therapy (HRT) delivered through a transdermal skin patch. It is used to treat moderate to severe menopausal symptoms such as hot flashes, night sweats, and vaginal symptoms caused by declining estrogen levels during menopause. The patch combines estradiol, a form of estrogen, with norethindrone acetate, a progestin that helps reduce the risk of endometrial (uterine) cancer in women who still have a uterus.

Applied directly to the skin, CombiPatch delivers hormones continuously into the bloodstream, helping maintain more consistent hormone levels than oral medications. Many women choose a transdermal patch because it is convenient, requires fewer doses each week, and may be an appropriate option for those who prefer not to take daily pills.

CombiPatch is typically applied to the lower abdomen and replaced twice weekly according to the prescribed schedule. It should not be placed on the breasts or areas where clothing may cause excessive rubbing. Patients should rotate application sites to help minimize skin irritation.

Like all hormone replacement therapies, CombiPatch is not appropriate for everyone. Treatment decisions should be individualized based on a person's symptoms, medical history, and risk factors. Hormone therapy may increase the risk of certain conditions, including blood clots, stroke, breast cancer, and cardiovascular disease in some individuals. Healthcare providers generally recommend using the lowest effective dose for the shortest duration needed to manage menopausal symptoms. Regular follow-up appointments are important to evaluate whether treatment should be continued and to monitor for potential side effects.

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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