Letairis
Letairis 30 Tablets
What is Letairis?
Ambrisentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and delay clinical worsening. By selectively blocking endothelin type-A receptors, ambrisentan reduces pulmonary vascular resistance, leading to decreased blood pressure in the pulmonary arteries. It is administered orally and requires careful monitoring due to potential liver toxicity and teratogenic effects.Side Effects
- Headache
- Flushing
- Nasal congestion
Warnings
- Contraindicated in pregnancy due to potential risk of harm to unborn baby.
- Potential for liver injury; regular monitoring of liver function tests is advised.
- Monitor hemoglobin levels as anemia may occur.
- Caution in patients with fluid retention or heart failure.
- Not recommended for patients with severe hepatic impairment.
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What is Letairis ?
Ambrisentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and delay clinical worsening. By selectively blocking endothelin type-A receptors, ambrisentan reduces pulmonary vascular resistance, leading to decreased blood pressure in the pulmonary arteries. It is administered orally and requires careful monitoring due to potential liver toxicity and teratogenic effects.- Headache
- Flushing
- Nasal congestion
- Swelling of legs and ankles (edema)
- Palpitations
- Dizziness
- Nausea
- Fatigue
- Contraindicated in pregnancy due to potential risk of harm to unborn baby.
- Potential for liver injury; regular monitoring of liver function tests is advised.
- Monitor hemoglobin levels as anemia may occur.
- Caution in patients with fluid retention or heart failure.
- Not recommended for patients with severe hepatic impairment.
- Possible interaction with other medications, notably cyclosporine.
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Letairis 30 Tablets
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.