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Neupro

Neupro 30 Patch 24 Hour

What is Neupro?

Neupro is used to treat the symptoms of Parkinson’s disease. There is not a Neupro generic drug currently available on the market. On average Neupro is priced at about $657 for a supply of 30, 1 mg/24 hr extended-release transdermal film. Luckily, you can use our Rx.com savings offer to receive a Neupro discount of up to 80% off the retail price at participating pharmacies near you.

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What is Neupro ?

Neupro is used to treat the symptoms of Parkinson’s disease. There is not a Neupro generic drug currently available on the market. On average Neupro is priced at about $657 for a supply of 30, 1 mg/24 hr extended-release transdermal film. Luckily, you can use our Rx.com savings offer to receive a Neupro discount of up to 80% off the retail price at participating pharmacies near you.
  • Lightheadedness, dizziness, fainting
  • Unusual changes in mood or behavior, behaviors you cannot control, seeing or hearing things that are not there
  • Twitching or muscle movements you cannot control (either new or worse than usual)
  • Unusual behavior, mood changes, confusion, or seeing or hearing things that are not there
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Changes in vision
  • Fever, sweating, confusion, uneven heartbeat, muscle stiffness, pain, tenderness, or weakness
  • Headache
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Skin rash, itching, swelling, or redness where the patch is worn
  • This medicine may cause new or worsened Parkinson disease symptoms, such as jerky muscle movements, during treatment.
  • This medicine may worsen RLS symptoms during or after treatment.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, high or low blood pressure, heart or blood vessel disease, lung or breathing problem (including asthma), dyskinesia (trouble with muscle control), sleeping problems, or mental problems. Tell your doctor if you had an allergy to sulfites.
  • This medicine may cause the following problems:HallucinationsUnusual changes in thoughts or behavior, including an urge to gamble, spend money, binge eat, or an increased sex driveChanges in blood pressure or heart rateIncreased weight or fluid retention (excess body fluids)Skin site reactions
  • This medicine may make you dizzy, drowsy, lightheaded, or faint. It may even cause you to fall asleep without warning while you drive, talk, or eat. Do not drive or do anything that could be dangerous until you know how this medicine affects you. Stand up slowly if you feel dizzy or lightheaded.
  • Remove this patch before you have a medical procedure that involves electricity, including MRI or cardioversion, because the patch contains aluminum. Make sure any doctor who treats you knows that you have this patch.
  • Keep the patch away from heat, especially from heating pads, electric blankets, hot tubs, or direct sunlight. Direct sunlight may cause skin discoloration.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Remove this patch before you have a medical procedure that involves electricity, such as MRI or cardioversion, because the patch contains aluminum. Make sure any doctor who treats you knows that you have this patch.
  • Heat may cause your skin to absorb too much of this medicine. Keep the patch away from heat, especially from heating pads, electric blankets, hot tubs, or direct sunlight.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Tell your doctor if you develop redness, swelling, or itchiness from the patch that lasts longer than a few days, becomes more severe, or spreads to areas outside the application site. Also, do not expose the area to direct sunlight until it heals. Direct sunlight may cause skin discoloration.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
What is Neupro used for?
Neupro (rotigotine) is FDA-approved for two uses: treating the signs and symptoms of idiopathic Parkinson's disease, either alone in early disease or combined with levodopa in more advanced disease, and treating moderate-to-severe primary restless legs syndrome (RLS). It's applied as a once-daily 24-hour transdermal patch.
Is Neupro the same as Requip or Mirapex?
No. Neupro (rotigotine), Requip (ropinirole), and Mirapex (pramipexole) are all non-ergot dopamine agonists used for Parkinson's disease and/or RLS, but they are different medications with different dosing forms — Neupro is a skin patch, while Requip and Mirapex are oral tablets. They aren't interchangeable, and switching between them should only be done under a prescriber's guidance.
How do you apply a Neupro patch correctly?
Neupro is applied once a day to clean, dry, intact skin and left in place for 24 hours before being replaced with a new patch at a different site. The label advises rotating application sites and avoiding the same spot for at least 14 days to reduce skin reactions, and keeping the patch away from heat sources and direct sunlight. Follow your prescriber's or the package instructions for exact application areas.
What are the side effects of the Neupro patch?
Beyond application-site skin reactions, Neupro's label warns of sudden sleep episodes (including while driving), orthostatic hypotension and fainting, hallucinations or psychotic-like behavior, and impulse-control problems such as compulsive gambling, shopping, eating, or hypersexuality. Dyskinesia can occur when Neupro is combined with levodopa. Stopping Neupro suddenly can cause withdrawal symptoms, so any dose changes should be guided by your provider.
Is there a generic version of Neupro (rotigotine)?
No. As of now, there is no FDA-approved generic version of the rotigotine transdermal patch, so Neupro is only available as the brand-name product.
How much does Neupro cost without insurance?
The price of Neupro without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Neupro?
Common side effects of Neupro may include: Lightheadedness, dizziness, fainting, Unusual changes in mood or behavior, behaviors you cannot control, seeing or hearing things that are not there, Twitching or muscle movements you cannot control (either new or worse than usual), Unusual behavior, mood changes, confusion, or seeing or hearing things that are not there, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Neupro?
Generic versions may be available for Neupro. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Neupro on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Neupro?
The cheapest pharmacy for Neupro depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Neupro near you.

Neupro Coupons & Prices

Neupro 30 Patch 24 Hour

Neupro Box — prescription drug image
Prescription
Neupro 30 patch 24 hour (0.1)
your area ·

Neupro prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
30 patch 24 hour · Box 30 $1,045.99 $834.97

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a Neupro coupon? Neupro (rotigotine transdermal system) is a once-daily patch used for Parkinson's disease and moderate-to-severe restless legs syndrome, and Rx.com can show you today's cash price at pharmacies near you — useful whether you're comparing it against the manufacturer's savings card or you don't have insurance coverage for it at all. Enter your ZIP above to see today's price before you decide where to fill it.

What Is Neupro and How Does It Work?

Neupro is the brand name for rotigotine, delivered continuously through a 24-hour transdermal patch rather than a pill. It belongs to the non-ergot dopamine agonist class and is FDA-approved for two separate uses: treating the signs and symptoms of idiopathic Parkinson's disease (it can be used alone in early disease or combined with levodopa in more advanced disease), and treating moderate-to-severe primary restless legs syndrome (RLS). The patch is applied once a day and rotated to a new skin site each time.

There is currently no FDA-approved generic version of rotigotine transdermal system, so Neupro is available only as the brand-name product.

Neupro Manufacturer Savings Card vs. an Rx.com Cash Coupon

Neupro's manufacturer, UCB, offers an official Neupro savings card program through its own website; like most manufacturer copay cards, it's generally intended for people with commercial (private/employer) insurance, and the exact terms, eligibility rules, and any dollar caps can change, so check the manufacturer's site directly for current details.

If you're uninsured, on Medicare, or your manufacturer card gets declined at the counter, an Rx.com cash coupon can still be used at most retail pharmacies — it isn't tied to having commercial insurance. Because Neupro is brand-only with no generic, and pharmacy cash prices for it can vary quite a bit from store to store, it's worth entering your ZIP above and comparing what a pharmacy quotes against your insurance copay (if any) before you pay. If cost is a major barrier, it's also reasonable to ask your prescriber or UCB about a patient assistance program.

How Neupro Compares to Other Parkinson's and RLS Medications

Neupro is one of several dopamine agonists used for Parkinson's disease and RLS, but it isn't interchangeable with the others — they're related medications, not the same drug, and only your prescriber can say which is right for you. Oral dopamine agonists in the same general class include Requip (ropinirole) and Mirapex (pramipexole), both taken as pills rather than a patch. For Parkinson's disease specifically, many patients also use or combine treatment with Sinemet or generic levodopa-carbidopa, which works through a different mechanism (levodopa is converted to dopamine in the brain rather than directly stimulating dopamine receptors). One advantage some patients and prescribers weigh with Neupro is its once-daily patch delivery, which avoids the peaks and valleys of an oral dose, but the best option depends on your specific symptoms, disease stage, and how your body tolerates each medication.

Neupro Safety Information

Neupro's label carries several important warnings common to dopamine agonists. It can cause sudden episodes of falling asleep during daily activities, including driving, sometimes without warning signs. It can also cause orthostatic hypotension (a drop in blood pressure on standing) and fainting, particularly when starting treatment. Some patients experience hallucinations or psychotic-like symptoms, or develop impulse-control problems such as compulsive gambling, shopping, eating, or hypersexuality — tell your provider right away if you notice any of these. The patch itself can cause significant skin reactions at the application site, so the label recommends applying it to a new location each day and avoiding the same spot for at least 14 days, and keeping the patch away from heat or direct sun. Neupro should not be stopped abruptly; your provider will taper the dose to avoid withdrawal symptoms, which can include confusion and high fever. This is general information, not medical advice — talk with your provider or pharmacist about your specific situation before starting or stopping Neupro.

Sources & accuracy

This Neupro information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Neupro on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.