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Spritam Tablet Disintegrating Soluble — prescription drug image

Spritam

Spritam 500MG

What is Spritam?

Spritam is a pyrrolidine anticonvulsant drug used to treat patients diagnosed with epilepsy. There is no generic version of this drug currently available on the market. Spritam costs around $962 for a supply of 60, 500 mg tablets, but luckily there are ways to save money. You can use our Rx.com Spritam savings card to save significantly on the retail price when you purchase your prescription from any locally participating pharmacies.

Prescription savings · · · ·

What is Spritam ?

Spritam is a pyrrolidine anticonvulsant drug used to treat patients diagnosed with epilepsy. There is no generic version of this drug currently available on the market. Spritam costs around $962 for a supply of 60, 500 mg tablets, but luckily there are ways to save money. You can use our Rx.com Spritam savings card to save significantly on the retail price when you purchase your prescription from any locally participating pharmacies.
  • Unusual bleeding or bruising
  • Fever, chills, cough, sore throat, body aches
  • Unusual changes in mood or behavior, depression, thoughts of hurting yourself
  • Problems with balance, coordination, or walking
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Extreme sleepiness, tiredness, or weakness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, high blood pressure, or a history of depression or mental health problems.
  • This medicine may cause the following problems:Unusual changes in mood or behaviorSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysisProblems with muscle control and coordinationHigh blood pressure
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • This medicine may make you dizzy, drowsy, or clumsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. Your seizures may return or occur more often if you stop using this medicine suddenly.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is Spritam used for?
Spritam (levetiracetam) is used to treat partial-onset seizures, and as an add-on therapy for myoclonic seizures in juvenile myoclonic epilepsy and for primary generalized tonic-clonic seizures in idiopathic generalized epilepsy, depending on the patient's age.
Is Spritam the same as Keppra?
They contain the same active ingredient, levetiracetam, but Spritam is a rapidly-disintegrating tablet made with 3D-printing technology, while Keppra is a conventional swallowed tablet. They are not interchangeable without your doctor's guidance.
Is there a generic version of Spritam?
Not of this exact fast-dissolving tablet formulation. Standard levetiracetam tablets and oral solution, which are chemically the same active ingredient in different forms, are available as lower-cost generics.
How do you take Spritam?
Spritam is placed on the tongue, where it disintegrates with a small sip of liquid — it isn't chewed or swallowed whole like a regular tablet. Follow the specific instructions your pharmacist provides.
Does Spritam have a black box warning?
No. Spritam does not carry an FDA boxed warning, but its label does include warnings about suicidal thoughts and behavior, DRESS (a rare hypersensitivity reaction), and the need to taper the dose gradually rather than stopping abruptly.
How much does Spritam cost without insurance?
The price of Spritam without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Spritam?
Common side effects of Spritam may include: Unusual bleeding or bruising, Fever, chills, cough, sore throat, body aches, Unusual changes in mood or behavior, depression, thoughts of hurting yourself, Problems with balance, coordination, or walking, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Spritam?
Generic versions may be available for Spritam. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Spritam on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Spritam?
The cheapest pharmacy for Spritam depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Spritam near you.

Spritam Coupons & Prices

Spritam 500MG

Spritam Tablet Disintegrating Soluble — prescription drug image
Prescription
Spritam 250mg (4)
your area ·

Spritam is a brand-name, rapidly-disintegrating oral tablet form of the anti-seizure medication levetiracetam, made using a 3D-printing process that lets it dissolve quickly with a sip of liquid. If you're searching for a Spritam coupon, Rx.com can help you compare cash prices at pharmacies near you, whether you have commercial insurance, Medicare, or no coverage at all.

What is Spritam and how does it work?

Spritam's active ingredient is levetiracetam, an anti-seizure (antiepileptic) medication. Its exact mechanism isn't fully understood, but it's thought to work by binding to a protein in the brain involved in regulating neurotransmitter release, which helps reduce abnormal electrical activity. Spritam is FDA-approved for partial-onset seizures in patients 4 years and older weighing more than 20 kg, as adjunctive therapy for myoclonic seizures in patients 12 and older with juvenile myoclonic epilepsy, and as adjunctive therapy for primary generalized tonic-clonic seizures in patients 6 and older with idiopathic generalized epilepsy. What sets Spritam apart from other levetiracetam products is its ZipDose formulation, an orally-disintegrating tablet made with a porous, 3D-printed structure that breaks apart in the mouth with a small amount of liquid, which can help patients who have difficulty swallowing pills.

Manufacturer savings vs. an Rx.com cash coupon

Spritam's manufacturer, Aprecia Pharmaceuticals, may offer savings support for eligible commercially-insured patients; program terms, eligibility, and enrollment vary and are subject to change, so check Aprecia's official site for current details. Manufacturer copay support generally isn't available if you're uninsured, on Medicare or Medicaid, or if your commercial plan doesn't cover Spritam. In those cases, an Rx.com cash coupon can be used at the pharmacy counter instead. Because Spritam's fast-dissolving tablet formulation is unique to this brand, there currently isn't a marketed generic equivalent of this exact orally-disintegrating tablet, though standard levetiracetam tablets and oral solution are widely available as lower-cost generics — ask your doctor whether a standard formulation is appropriate for you if cost is a concern.

Other seizure medications

Levetiracetam is also sold under other brand names, including Keppra and the extended-release Keppra XR, in standard tablet and oral solution forms. Depending on your seizure type and history, your neurologist may also consider other antiepileptic drugs such as lamotrigine or valproic acid. Switching between antiepileptic medications or formulations should only be done under a doctor's supervision, since seizure control can be sensitive to changes in dose or absorption.

Safety information

Like other antiepileptic drugs, levetiracetam carries a warning about an increased risk of suicidal thoughts or behavior; patients and caregivers should watch for new or worsening depression, anxiety, agitation, or unusual changes in mood or behavior. Levetiracetam has also been associated with a rare but serious hypersensitivity reaction called DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms), which can be life-threatening and typically develops within the first several weeks of treatment. Don't stop taking levetiracetam abruptly, as this can increase the risk of seizures; your doctor will typically taper the dose gradually. This is general information, not medical advice — talk to your prescriber about your specific situation.

Sources & accuracy

This Spritam information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Spritam on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.