Tigecycline Coupons & Prices

Looking for a tigecycline coupon? Tigecycline (the generic form of the brand Tygacil) is a hospital antibiotic given only by IV infusion, so it is not a medicine you pick up and take at home. Because it is available as a generic, it is generally lower cost than brand-name Tygacil, but the price a pharmacy or facility charges can vary widely. Rx.com compares cash prices across more than 60,000 pharmacies so you can find today's best price. Enter your ZIP above to see current pricing near you.

What is tigecycline and how does it work?

Tigecycline is a glycylcycline antibiotic, a class closely related to the tetracyclines. It is FDA-approved for adults 18 and older and is given only by intravenous (IV) infusion in a hospital or clinical setting, not as a pill you take by mouth. Doctors use it to treat complicated skin and skin-structure infections, complicated intra-abdominal (belly) infections, and community-acquired bacterial pneumonia caused by bacteria that are susceptible to it. It works by stopping bacteria from making the proteins they need to grow and multiply.

Tigecycline is generally reserved for infections that cannot be treated with other antibiotics, because of a higher risk of death seen in studies (see safety below). It is sometimes used off-label by specialists for serious multidrug-resistant infections, such as certain carbapenem-resistant bacteria, but that decision belongs to your care team. Tygacil is the original brand name; the generic tigecycline is now available.

Tigecycline cost and savings without insurance

Because tigecycline is available as a generic, it is usually more affordable than the brand-name Tygacil. That said, this is an IV hospital antibiotic, so cash prices can differ a lot from one pharmacy or supplier to the next, which is exactly why comparing matters. Rx.com checks prices across more than 60,000 pharmacies so you are not stuck paying the first price you are quoted.

We do not list a set dollar figure here because prices change and are shown live. Enter your ZIP above to see today's price in your area. There is no manufacturer savings card for tigecycline; if you are worried about cost, ask the hospital pharmacy or your provider about options, since terms can vary.

Tigecycline vs. related antibiotics

Tigecycline belongs to the tetracycline family of antibiotics but is a newer glycylcycline built to work against some bacteria that resist older drugs. It differs from common oral tetracyclines you may know, such as doxycycline and minocycline, which are taken as pills for a wide range of infections. Tigecycline is IV-only and is reserved for more serious, harder-to-treat infections.

Two closer relatives are eravacycline (another IV tetracycline-class antibiotic) and omadacycline (available in both IV and oral forms). Which antibiotic is right depends on the type of infection, the specific bacteria involved, and your medical history, so this choice is made by your doctor. This information is educational and is not a substitute for professional medical advice.

Tigecycline safety and side effects

Tigecycline carries a boxed warning, the FDA's strongest warning. In pooled clinical trials, patients treated with tigecycline had a higher rate of death from all causes than those given comparison antibiotics, with the greatest risk in ventilator-associated pneumonia, which is not an approved use. For this reason it should be reserved for situations where other antibiotics are not suitable. It is not indicated for diabetic foot infections or for hospital-acquired or ventilator-associated pneumonia.

Like other tetracycline-class drugs, tigecycline can cause permanent tooth discoloration and affect enamel development if used in later pregnancy or in children under 8, and it may harm an unborn baby. Other serious risks include acute pancreatitis (rarely fatal), severe allergic reactions (people allergic to tetracyclines may react to it), liver problems, low fibrinogen with bleeding, and Clostridioides difficile-associated diarrhea. The most common side effects are nausea and vomiting. This is not medical advice; discuss any questions or symptoms with your provider or care team.