Irbesartan
Irbesartan
What is Irbesartan?
Irbesartan (Avapro) is a prescription medication used to treat high blood pressure (hypertension) and help protect kidney function in certain people with type 2 diabetes. As an angiotensin II receptor blocker (ARB), it relaxes blood vessels to improve blood flow and reduce the risk of heart attack, stroke, and kidney damage.
Side Effects
- Lightheadedness, dizziness, fainting
- Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
- Change in how much or how often you urinate
Warnings
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, or heart failure.
- This medicine may cause kidney problems.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. This is more likely to happen when you first use the medicine or if you become dehydrated. Stand or sit up slowly if you are dizzy.
Prescription savings · · · ·
What is Irbesartan ?
Irbesartan (Avapro) is a prescription medication used to treat high blood pressure (hypertension) and help protect kidney function in certain people with type 2 diabetes. As an angiotensin II receptor blocker (ARB), it relaxes blood vessels to improve blood flow and reduce the risk of heart attack, stroke, and kidney damage.
- Lightheadedness, dizziness, fainting
- Confusion, weakness, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
- Change in how much or how often you urinate
- Rapid weight gain, swelling in your hands, ankles, or feet
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, or heart failure.
- This medicine may cause kidney problems.
- This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. This is more likely to happen when you first use the medicine or if you become dehydrated. Stand or sit up slowly if you are dizzy.
- Do not stop using the medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Irbesartan Coupons & Prices
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Looking for an irbesartan coupon? Irbesartan is the low-cost generic form of Avapro, an angiotensin II receptor blocker (ARB) used to treat high blood pressure and to protect the kidneys in people with type 2 diabetes. Because it is already available as a generic, the cash price is usually modest, but the exact amount can vary widely from one pharmacy to the next. Enter your ZIP above to see today's price and compare your discount across more than 60,000 pharmacies with Rx.com, no insurance required.
What is irbesartan and how does it work?
Irbesartan is an angiotensin II receptor blocker, or ARB. It is FDA-approved to treat hypertension (high blood pressure), either on its own or together with other blood-pressure medicines. It is also approved to treat diabetic nephropathy (kidney disease) in people who have both type 2 diabetes and high blood pressure, where it helps slow the progression of kidney damage.
It works by blocking the action of angiotensin II, a natural substance that tightens blood vessels. When irbesartan blocks it, blood vessels relax and widen, which lowers blood pressure and eases strain on the heart and kidneys. It is sold under the brand names Avapro (irbesartan) and Avalide (irbesartan combined with the water pill hydrochlorothiazide). Irbesartan is not a controlled substance.
How much does irbesartan cost without insurance?
Irbesartan is available as a generic, which usually keeps the cash price affordable compared with the brand-name Avapro. That said, generic prices are not the same everywhere. The same prescription can cost noticeably more at one pharmacy than at another down the street, so it pays to compare before you fill.
Rx.com checks discount prices across more than 60,000 pharmacies so you can find a lower cash price near you, even if you do not have insurance. Enter your ZIP above to see today's price and print or show your free coupon at the pharmacy counter.
Irbesartan alternatives and related ARBs
Irbesartan belongs to the same family as several other angiotensin II receptor blockers. If you and your doctor are weighing options, common alternatives include losartan, valsartan, olmesartan, telmisartan, and candesartan. These medicines work in a similar way but differ in dosing and cost.
If your prescriber wants the added blood-pressure effect of a water pill, there is also a combination version, irbesartan-hydrochlorothiazide (brand name Avalide). Only your provider can decide which option is right for you, but comparing the cash price of each on Rx.com can help you have that conversation.
Safety information you should know
Irbesartan carries a boxed warning for fetal toxicity. Medicines that act on the renin-angiotensin system can cause injury or death to a developing baby, especially during the second and third trimesters of pregnancy. If you become pregnant or think you might be, stop taking irbesartan and contact your provider right away.
Other possible risks include low blood pressure (particularly if you are low on fluids or salt), high potassium levels, and reduced kidney function. Because of this, irbesartan should generally not be combined with ACE inhibitors or aliskiren, especially in people with diabetes, and it should not be used with potassium-sparing diuretics or potassium supplements without monitoring. A serious allergic reaction called angioedema is rare. This is general information, not medical advice, so talk with your doctor or pharmacist about your full health history and any other medicines you take.
This Irbesartan information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Irbesartan on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.