Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Shingrix Suspension Reconstituted — prescription drug image

Shingrix

Shingrix 50MCG/0.5ML

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Shingrix?

Shingrix is a vaccine that helps prevent shingles, a painful skin rash caused by the same virus that leads to chickenpox. It can also help reduce the risk of long-lasting nerve pain that may occur after shingles.

Prescription savings · · · ·

What is Shingrix ?

Shingrix is a vaccine that helps prevent shingles, a painful skin rash caused by the same virus that leads to chickenpox. It can also help reduce the risk of long-lasting nerve pain that may occur after shingles.

Source: MedlinePlus, U.S. National Library of Medicine

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Sudden numbness or weakness in your arms or legs
  • Tell your doctor if you are pregnant or breastfeeding, or if you have a weak immune system.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • This vaccine may increase your risk for nervous system problems, including Guillain-Barré syndrome.
How much does Shingrix cost without insurance?
The cash price for Shingrix varies by pharmacy and location, and because it is a two-dose series you will pay for each dose. There is no generic, so an Rx.com cash coupon is one of the main ways to lower the out-of-pocket cost if you are uninsured or your plan does not cover it. Enter your ZIP above to see today's price at pharmacies near you.
How effective is Shingrix and how long does the protection last?
Shingrix is highly effective at preventing shingles in adults 50 and older when both doses are received. Because protection depends on completing the full two-dose series, it is important to get the second dose on schedule. Ask your provider about how long protection is expected to last for your situation.
What are the most common side effects of the Shingrix vaccine?
The most common side effects are pain, redness, and swelling at the injection site, plus muscle aches, tiredness, headache, shivering, fever, and stomach upset. These usually go away within 2 to 3 days. About 1 in 6 people have a reaction strong enough to briefly limit normal activities.
How many doses of Shingrix do you need and how far apart?
Shingrix is a two-dose series. The second dose is normally given 2 to 6 months after the first. People who are immunocompromised may use a shorter interval of 1 to 2 months between doses. Both doses are needed for full protection.
Who should not get the Shingrix vaccine?
You should not get Shingrix if you have had a severe allergic reaction to any ingredient in the vaccine or to a previous dose. Let your provider know if you are feeling ill or have any allergies. Shingrix is not a live vaccine, so it can be given to people with weakened immune systems. Your provider can confirm whether it is appropriate for you.
How much does Shingrix cost without insurance?
The price of Shingrix without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Shingrix?
Common side effects of Shingrix may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Sudden numbness or weakness in your arms or legs. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Shingrix?
Generic versions may be available for Shingrix. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Shingrix on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Shingrix?
The cheapest pharmacy for Shingrix depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Shingrix near you.

Shingrix Coupons & Prices

Shingrix 50MCG/0.5ML

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Shingrix Suspension Reconstituted — prescription drug image
Prescription
Shingrix 50mcg/0.5ml (1)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Shingrix coupon? Shingrix is the brand-name recombinant zoster vaccine (RZV) that is FDA-approved to help prevent shingles (herpes zoster) in adults 50 and older, as well as in adults 18 and older who are at increased risk of shingles because of a weakened immune system. It is given as a two-dose series and has no generic version. Because it is often billed as a pharmacy vaccine, the price you pay can vary a lot from one location to another. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you and compare it against what you would pay out of pocket.

What is Shingrix and how does it work?

Shingrix (recombinant zoster vaccine, adjuvanted with AS01B) is a non-live, recombinant subunit vaccine used to prevent shingles, the painful rash caused by reactivation of the same virus that causes chickenpox. Because it is not a live vaccine, it can be given to people whose immune systems are weakened. It is given as a two-dose series: the second dose normally follows 2 to 6 months after the first, and immunocompromised patients may use a shortened 1-to-2-month interval.

Shingrix is FDA-approved to prevent shingles in adults 50 and older, and in adults 18 and older who are or will be at increased risk of shingles due to immunodeficiency or immunosuppression from a disease or its treatment. It is not used to prevent primary chickenpox (varicella), and it does not treat an active shingles outbreak or the lingering nerve pain (postherpetic neuralgia) that can follow one.

Shingrix cost: manufacturer support vs. an Rx.com cash coupon

Shingrix does not have a generic, so there is no lower-cost substitute at the pharmacy counter, and the manufacturer (GSK) does not offer a general commercial copay savings card for it the way some brand medications do. Many people are covered for Shingrix at no cost through Medicare Part D or commercial insurance, but coverage and out-of-pocket costs vary by plan, so it is worth confirming your benefit before you go.

If you are uninsured, between plans, or your coverage does not pick up the full cost, an Rx.com cash coupon can help. Our coupon is a cash-price discount you can use whether or not you have insurance, and it is handy when a plan will not cover the dose or you want to compare the cash price. GSK also runs a patient-assistance program, GSK for You, for eligible people who cannot afford their medicines; eligibility and terms are set by the manufacturer and can change, so check their official site for current details. To see your price, enter your ZIP above and compare pharmacies near you.

How Shingrix compares to other shingles vaccines

Shingrix is currently the only shingles vaccine marketed in the United States. The older live vaccine, Zostavax, was discontinued and is no longer sold in the U.S., so Shingrix is the recommended option for eligible adults. Because Shingrix is not a live vaccine, it can be given to people with weakened immune systems, which the older live vaccine could not.

Shingrix protects against shingles, not chickenpox, and it is not interchangeable with the childhood chickenpox (varicella) vaccine. Talk with your pharmacist or provider about the right timing if you have had shingles before or received the older vaccine in the past.

Shingrix safety and side effects

Shingrix has no boxed warning. The most common reactions are soreness, redness, and swelling where the shot is given, along with body-wide effects such as muscle aches, tiredness, headache, shivering, fever, and upset stomach. These usually clear up within 2 to 3 days. About 1 in 6 people have reactions strong enough to briefly limit their normal activities, which is a sign your immune system is responding.

An increased risk of Guillain-Barre syndrome (GBS) has been observed within 42 days after vaccination and is noted on the label. Fainting (syncope) can happen with any injection, and rare severe allergic reactions are possible. Shingrix should not be given to anyone with a history of a severe allergic reaction to any ingredient in the vaccine or to a previous dose. This information is not medical advice; talk with your provider or pharmacist about whether Shingrix is right for you.

Sources & accuracy

This Shingrix information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Shingrix on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Browse more medications: starting with S · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®