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Stiolto Respimat Inhaler — prescription drug image

Stiolto Respimat

Stiolto Respimat

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What is Stiolto Respimat?

Stiolto Respimat is a prescription inhaler used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD). It combines two bronchodilators that work together to relax the airway muscles, improve breathing, and help reduce COPD symptoms such as shortness of breath and wheezing.

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What is Stiolto Respimat ?

Stiolto Respimat is a prescription inhaler used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD). It combines two bronchodilators that work together to relax the airway muscles, improve breathing, and help reduce COPD symptoms such as shortness of breath and wheezing.

  • Chest pain, fast, pounding, or uneven heartbeat
  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting
  • Increased trouble breathing
  • Seizures or tremors
  • Dizziness, lightheadedness, or fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, eye pain, seeing halos around objects
  • Decrease in how much or how often you urinate, painful or difficult urination
  • Increased hunger or thirst, weight loss
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems (including QT prolongation), high blood pressure, diabetes, glaucoma, thyroid problems, prostate problems, trouble urinating, electrolyte imbalance, or seizures. Tell your doctor if you are allergic to atropine.
  • This medicine may cause the following problems:Increased risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take this medicine without an inhaled steroidParadoxical bronchospasm (increased trouble breathing), which can be life-threateningHigh blood pressureHeart rhythm problemsEye or vision problemsHigh blood sugar levels
  • Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use your other medicine only during a severe COPD attack.
  • Do not use this medicine if you are having a severe COPD attack, or if symptoms of a COPD attack has already started. Your doctor may prescribe another medicine for you to use in case of an acute COPD attack. Make sure you always have your rescue medicine with you to treat sudden symptoms.
  • Inhalation routeIf any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Stiolto Respimat used for?
Stiolto Respimat is a once-daily maintenance inhaler used to treat long-term airflow obstruction in chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It combines tiotropium and olodaterol to help keep airways open. It is not a rescue inhaler and is not used to relieve sudden breathing problems or a COPD flare-up.
Is there a generic version of Stiolto Respimat?
No. Stiolto Respimat is currently available only as a brand-name product; there is no generic version. Because of that, the two main ways to lower your cost are the manufacturer savings card (generally for people with commercial insurance) and a cash discount coupon, which can help if you are uninsured or on Medicare. Enter your ZIP above to see today's cash price.
How much does Stiolto Respimat cost with a savings card?
Prices and savings-card terms change and vary by pharmacy and coverage, so we do not list a fixed dollar amount. The manufacturer savings card from Boehringer Ingelheim is generally limited to commercial insurance; check the official page for current eligibility and terms. To see the Rx.com cash price near you, enter your ZIP above and compare it with the card to use whichever is lower.
Can Stiolto Respimat be used for asthma?
No. Stiolto Respimat is not approved to treat asthma. It carries a boxed warning because long-acting beta2-agonists like olodaterol can increase the risk of asthma-related death. It is approved only for long-term maintenance treatment of COPD. Talk with your provider about the right treatment if you have asthma.
What is the difference between Stiolto Respimat and Spiriva?
Spiriva and Spiriva Respimat contain only tiotropium, a single long-acting anticholinergic (LAMA) bronchodilator. Stiolto Respimat contains that same tiotropium plus olodaterol, a long-acting beta2-agonist (LABA), so it provides two types of bronchodilation in one inhaler. Both are once-daily COPD maintenance treatments; your provider can advise which is right for you.
How much does Stiolto Respimat 4GM of 2.5-2.5MCG/ACT cost without insurance?
The price of Stiolto Respimat 4GM of 2.5-2.5MCG/ACT without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Stiolto Respimat 4GM of 2.5-2.5MCG/ACT?
Common side effects of Stiolto Respimat 4GM of 2.5-2.5MCG/ACT may include: Chest pain, fast, pounding, or uneven heartbeat, Dry mouth, increased thirst, muscle cramps, nausea, vomiting, Increased trouble breathing, Seizures or tremors, Dizziness, lightheadedness, or fainting. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Stiolto Respimat 4GM of 2.5-2.5MCG/ACT?
Generic versions may be available for Stiolto Respimat 4GM of 2.5-2.5MCG/ACT. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Stiolto Respimat 4GM of 2.5-2.5MCG/ACT on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Stiolto Respimat 4GM of 2.5-2.5MCG/ACT?
The cheapest pharmacy for Stiolto Respimat 4GM of 2.5-2.5MCG/ACT depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Stiolto Respimat 4GM of 2.5-2.5MCG/ACT near you.

Stiolto Respimat Coupons & Prices

Stiolto Respimat

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Stiolto Respimat Inhaler — prescription drug image
Prescription
Stiolto Respimat 4gm of 2.5-2.5mcg/act (60 inhalations) (3)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Stiolto Respimat coupon? Stiolto Respimat is a brand-name, once-daily maintenance inhaler used to treat long-term airflow obstruction in chronic obstructive pulmonary disease (COPD). Because it is a brand-only medicine with no generic version yet, the price can be high without help. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you, and compare it against the manufacturer savings card so you pay the lowest amount available to you.

What is Stiolto Respimat and how does it work?

Stiolto Respimat is a combination inhalation spray that pairs two long-acting bronchodilators: tiotropium bromide, a long-acting anticholinergic (LAMA), and olodaterol, a long-acting beta2-agonist (LABA). Together they relax and open the airways so it is easier to breathe. It is approved for the long-term, once-daily maintenance treatment of airflow obstruction in COPD, including chronic bronchitis and emphysema.

The usual dose is two inhalations once a day, taken at the same time each day, using the Respimat inhaler. Stiolto Respimat is a maintenance medicine only. It is not a rescue inhaler and should not be used to relieve sudden breathing problems or an acute COPD flare-up. It is also not approved to treat asthma.

Manufacturer savings card vs. the Rx.com cash coupon

There is no generic version of Stiolto Respimat, so the two main ways to lower your cost are the manufacturer savings card and a cash discount coupon. Boehringer Ingelheim offers a Stiolto Respimat savings card that may reduce your out-of-pocket cost. Manufacturer cards like this are generally limited to people with commercial (private) insurance and are typically not available if you have Medicare, Medicaid, or other government coverage. Terms, eligibility, and any savings amounts vary and are set by the manufacturer, so check the official page for current details: Stiolto Respimat savings card.

The Rx.com cash coupon works differently. It is a cash-price discount, so it can help if you are uninsured, if you have Medicare or another plan that the manufacturer card excludes, or if the savings card is declined at the pharmacy. You cannot combine a cash coupon with insurance on the same fill, but you can compare both and use whichever is lower. Enter your ZIP above to see today's Rx.com price. If you are having trouble affording your medication, it is also worth asking Boehringer Ingelheim or your provider about patient assistance options.

Alternatives and how Stiolto compares

Stiolto Respimat is one of several once-daily COPD maintenance inhalers, and the right choice depends on your history and what your provider recommends. A common question is how it differs from Spiriva. Spiriva Respimat and Spiriva contain only tiotropium (a single LAMA bronchodilator), while Stiolto Respimat combines that same tiotropium with olodaterol, adding a LABA for dual bronchodilation.

Other maintenance inhalers your provider may discuss include Anoro Ellipta (another LAMA/LABA combination), triple-therapy inhalers such as Trelegy Ellipta that add an inhaled steroid, and steroid-containing options like Breo Ellipta and Symbicort. Combivent Respimat is a different type of inhaler and is not a once-daily maintenance product. Do not switch or stop any inhaler on your own; talk with your provider about which fits your COPD.

Safety and side effects to know

Stiolto Respimat carries a boxed warning: long-acting beta2-agonists (LABAs) such as olodaterol increase the risk of asthma-related death, which is why this medicine is not approved for asthma. It is also not for acute bronchospasm or rescue use. Do not exceed the recommended dose, and do not use it together with other LABA-containing medicines.

Possible effects include paradoxical bronchospasm (sudden worsening of breathing right after a dose), immediate allergic reactions, effects on the heart such as increased heart rate or blood pressure, worsening of narrow-angle glaucoma, urinary retention, and changes in blood potassium or blood sugar. Use extra caution if you have heart problems, a seizure history, thyroid disease, or glaucoma. This information is not medical advice. Tell your doctor about your full health history and all medicines you take, and seek care right away if breathing suddenly worsens.

Sources & accuracy

This Stiolto Respimat information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Stiolto Respimat on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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