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Lose weight with GLP-1 treatment, 100% online

Compare licensed telehealth providers offering semaglutide and tirzepatide programs. Complete a quick intake from home, no in-person visit required.

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A licensed clinician must evaluate you before any prescription can be issued. Not everyone will be approved. This page compares licensed telehealth providers — some links are affiliate links.

How online GLP-1 treatment works
Three steps. Takes about 10 minutes to start.
1
Complete a quick intake
Answer health questions online. No video call or in-person visit required in most cases.
2
A licensed provider reviews
A real clinician reviews your health history and determines if GLP-1 treatment is appropriate for you.
3
Medication ships to you
If approved, your medication ships directly to your door. Ongoing check-ins help you adjust and stay on track.
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Why people choose online GLP-1 programs
Far cheaper than brand-name Online programs are typically a fraction of what brand-name Wegovy or Ozempic costs at a pharmacy without coverage.
No in-person visit needed Complete everything online. No waiting room, no scheduling a doctor's appointment.
Real clinical oversight Licensed clinicians review every case and provide ongoing dose guidance as you progress.
Ships to your door Medication delivered directly to you. No pharmacy pickup required.
Common questions
Yes. The providers on this page are licensed telehealth companies regulated under U.S. state medical law. Every prescription is reviewed by a licensed clinician. Medications are dispensed from licensed U.S. pharmacies. These are the same types of services advertised on TV and recommended by doctors.
No. These programs are designed as cash-pay alternatives to insurance, and are typically a fraction of what brand-name Wegovy or Ozempic costs at a pharmacy without coverage.
Most programs offer compounded semaglutide (the same active ingredient as Wegovy and Ozempic, in a compounded preparation that is not FDA-approved) and/or compounded tirzepatide (the same active ingredient as Zepbound and Mounjaro, in a compounded preparation that is not FDA-approved). Some also offer brand-name options depending on insurance. A clinician will help determine what's right for you.
Compounded semaglutide and tirzepatide contain the same active ingredient as the brand-name medications, but the compounded preparations are not FDA-approved finished products. They are prepared by state-licensed 503A pharmacies or FDA-registered 503B outsourcing facilities, and the FDA does not review them for safety, effectiveness, or quality. Quality can vary by pharmacy — reputable providers work with accredited compounding pharmacies and disclose their sources. Your clinician can address any specific concerns.
Pricing depends on the provider, medication, and dose, and typically includes the clinician evaluation, medication, and ongoing support. Compare the providers above and visit each one for current pricing.
Eligibility is determined by a licensed clinician after reviewing your health history. Most programs require a BMI of 27+ with a weight-related condition, or BMI 30+. GLP-1 medications are not appropriate for everyone — certain thyroid conditions, pregnancy, and other factors may disqualify. The intake process is free and fast.
The most common side effects are nausea, stomach discomfort, and changes in appetite — especially when starting or increasing doses. These typically improve over time. Most programs include provider support to help manage side effects and adjust dosing. Serious side effects are rare.
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Other options to compare

Not sure Yucca Health is right for you? Here are other licensed programs worth considering.

Eden

A telehealth service offering doctor-led weight management plans. Known for transparent pricing with no hidden fees or membership costs.

  • Same price at every dose level — no price surprises as you titrate up
  • No membership fees or contracts
  • Doctor-led treatment plans
  • Unlimited provider support
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Elevate Health

An online weight management program that pairs patients with healthcare providers for GLP-1 evaluation. Focuses on a streamlined digital experience.

  • 100% online consultation process
  • Regular check-ins with care team
  • Free shipping on medications
  • No contracts or commitments
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Important Safety Information

Rx.com does not provide medical advice, diagnosis, or treatment. This page compares third-party telehealth services. A licensed clinician must evaluate you before any prescription can be issued. Not everyone will qualify.

GLP-1 medications are not appropriate for people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Always disclose your full medical history to your provider.

Prices and provider offerings may change. Information reviewed September 4, 2026.

About compounded medications: Compounded medications are not FDA-approved products. They may be prepared by state-licensed 503A pharmacies or FDA-registered 503B outsourcing facilities, but the finished compounded product is not reviewed by the FDA for safety, effectiveness, or quality, and it is not equivalent to, endorsed by, or affiliated with any brand-name medication or manufacturer. A prescription is required and eligibility is determined by a licensed provider. Always consult a licensed healthcare provider to decide what is appropriate for you.

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