Betamethasone Dipropionate
Betamethasone Dipropionate 45GM of 0.05%
What is Betamethasone Dipropionate?
Betamethasone Dipropionate is a generic drug used to relieve inflammation caused by certain skin conditions. The average Betamethasone Dipropionate price is about $39 for a supply of 15 grams, 0.05% topical cream. You can use our Rx.com savings offer to get a Betamethasone Dipropionate discount of up to 80% off of the retail price at participating pharmacies near you.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision or changes in vision, eye pain
- Severe itching, burning, or skin irritation
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- If your symptoms do not improve after 2 to 4 weeks of treatment, or if they get worse, check with your doctor.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- This medicine may cause the following problems:Adrenal gland problemsHigh blood sugarEye problems (including cataracts, glaucoma)
- Tell your doctor if you are pregnant or breastfeeding.
Prescription savings · · · ·
What is Betamethasone Dipropionate ?
Betamethasone Dipropionate is a generic drug used to relieve inflammation caused by certain skin conditions. The average Betamethasone Dipropionate price is about $39 for a supply of 15 grams, 0.05% topical cream. You can use our Rx.com savings offer to get a Betamethasone Dipropionate discount of up to 80% off of the retail price at participating pharmacies near you.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision or changes in vision, eye pain
- Severe itching, burning, or skin irritation
- Color changes on the skin, dark freckles, easy bruising, muscle weakness
- Redness, swelling, drainage, or pus on the skin
- Weight gain around your neck, upper back, breast, face, or waist
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- If your symptoms do not improve after 2 to 4 weeks of treatment, or if they get worse, check with your doctor.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- This medicine may cause the following problems:Adrenal gland problemsHigh blood sugarEye problems (including cataracts, glaucoma)
- Tell your doctor if you are pregnant or breastfeeding.
Betamethasone Dipropionate Coupons & Prices
Betamethasone Dipropionate 45GM of 0.05%
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Looking for a betamethasone dipropionate coupon? Betamethasone dipropionate is a prescription topical corticosteroid (available as a cream, ointment, lotion, or gel) used to relieve the inflammation and itching of many skin conditions. It is available as a lower-cost generic, but the cash price can vary widely from one pharmacy to the next, so comparing pharmacies is worth it. Rx.com compares cash prices at over 60,000 U.S. pharmacies so you can see the lowest price near you and use a free discount coupon at the counter, even without insurance. Enter your ZIP above to see today's price.
What is betamethasone dipropionate and how does it work?
Betamethasone dipropionate is a topical corticosteroid (a glucocorticoid). It works by calming the skin's inflammatory response, which reduces redness, swelling, and itching. It is FDA-approved to relieve the inflammatory and itchy (pruritic) symptoms of corticosteroid-responsive skin conditions in people 13 years and older. It is commonly used for conditions such as eczema (atopic dermatitis), contact dermatitis, and psoriasis (including combination products that pair it with calcipotriene).
Its strength depends on the formulation. Plain cream is medium-potency, while the augmented or optimized-vehicle versions are super-high-potency. It comes as a cream, ointment, lotion, and gel, and is usually applied once or twice daily to the affected skin as directed by your doctor.
How much does betamethasone dipropionate cost without insurance?
Betamethasone dipropionate is available as a generic, which is typically much less expensive than the brand-name versions such as Diprolene. Even so, the cash price is not the same everywhere: two pharmacies in the same town can charge very different amounts for the same tube, and the price also depends on the form (cream, ointment, lotion, or gel), the strength, and the size. That is exactly why comparing matters.
If you are paying out of pocket, a free Rx.com discount coupon can help lower the cash price at the pharmacy counter, and you do not need insurance to use it. Because prices change and are set locally, we show the live price on this page. Enter your ZIP above to see today's price near you and compare across 60,000+ pharmacies.
Betamethasone dipropionate vs. brand names and similar steroids
Betamethasone dipropionate is the generic form of brand-name products including Diprolene, and it also appears in combination products with calcipotriene such as calcipotriene/betamethasone for psoriasis. Because the generic and brand contain the same active ingredient, many people can save by choosing the generic.
It is one of several topical steroids of differing strengths. Your doctor may consider a different option depending on how strong a steroid your skin condition needs and where it will be applied:
- Betamethasone valerate — a related, generally milder betamethasone ester
- Clobetasol propionate — a very strong (super-high-potency) topical steroid
- Triamcinolone acetonide — a common medium-potency option
- Hydrocortisone — a low-potency steroid for milder or more sensitive areas
Safety and important precautions
This information is educational and is not medical advice — always follow your doctor's or pharmacist's directions. Betamethasone dipropionate has no boxed warning, but because it can be absorbed through the skin, it can occasionally cause reversible effects on the body such as HPA-axis suppression, Cushing's syndrome, high blood sugar, or sugar in the urine. This risk is higher with the augmented (super-high-potency) forms, when treating large areas, when the skin is covered (occlusion), with prolonged use, and in children, who absorb proportionally more.
To use it safely: the augmented products have dosing limits (for example, do not exceed about 50 g per week) and should not be used for more than 2 consecutive weeks. Avoid using it on the face, groin, or underarms unless your doctor directs it, and avoid occlusive dressings. Local skin reactions can include thinning of the skin (atrophy), stretch marks (striae), burning, itching, folliculitis, and small visible blood vessels (telangiectasia). Stop use and contact your provider if irritation or infection develops.
This Betamethasone Dipropionate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Betamethasone Dipropionate on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.