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Calcipotriene-Betameth Diprop

Calcipotriene-Betameth Diprop 60GM of 0.005-0.064%

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What is Calcipotriene-Betameth Diprop?

Calcipotriene-Betamethasone Dipropionate is a combination topical medication used for the treatment of psoriasis. It merges calcipotriene, a vitamin D analogue that reduces skin cell production, with betamethasone dipropionate, a potent corticosteroid that alleviates inflammation and suppresses immune response. This dual-action cream or ointment is effective in improving psoriatic symptoms and is commonly prescribed for adults with plaque psoriasis.

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What is Calcipotriene-Betameth Diprop ?

Calcipotriene-Betamethasone Dipropionate is a combination topical medication used for the treatment of psoriasis. It merges calcipotriene, a vitamin D analogue that reduces skin cell production, with betamethasone dipropionate, a potent corticosteroid that alleviates inflammation and suppresses immune response. This dual-action cream or ointment is effective in improving psoriatic symptoms and is commonly prescribed for adults with plaque psoriasis.
  • Burning, pain, redness, or thinning of the skin
  • Increased hunger, thirst, or urination
  • Blurred vision or other change in vision, eye pain
  • Cold feeling, weakness, tiredness, nausea, vomiting, weight loss
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe itching or worsening of psoriasis
  • Change of color or swelling of the skin where the medicine is applied, dark freckles, easy bruising, muscle weakness
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, Cushing syndrome, diabetes, eye or vision problems (including cataracts or glaucoma), any skin or scalp infection, or thin skin at the site to be treated.
  • This medicine may cause the following problems:Adrenal gland problemsHigh blood sugarIncreased risk of cataracts or glaucomaEye or vision problemsAllergic contact dermatitis
  • This medicine may cause calcium to build up in your body if you use too much of it. Too much calcium may increase your risk for adrenal gland problems.
  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is calcipotriene and betamethasone dipropionate used for?
It's FDA-approved to treat plaque psoriasis on the skin. Depending on the formulation, it's used on the body in adults or on the scalp in adolescents and adults, applied once daily for a limited course before your provider checks your progress.
Is calcipotriene/betamethasone a steroid, and is it safe for long-term use?
Yes — the betamethasone dipropionate component is a high-potency topical corticosteroid. Because of the risks of skin thinning and whole-body steroid absorption with extended use, it's generally prescribed for a limited number of weeks at a time rather than continuous long-term use, with your provider reassessing your skin periodically.
What's the difference between Taclonex, Enstilar, and Wynzora?
All three contain the same two active ingredients but in different forms. Taclonex is an ointment or topical suspension (and now has a generic version). Enstilar is an aerosol foam approved for ages 12 and up. Wynzora is a cream formulation approved for adults. Your provider picks the form based on where you have psoriasis and what's easiest for you to use.
How much calcipotriene-betamethasone can you use per week?
Each formulation has its own maximum weekly amount listed on the product label, because using more than that raises the risk of elevated calcium levels from the calcipotriene component. Check the label for your specific product or ask your pharmacist what the limit is for the version you were prescribed.
Can you use calcipotriene and betamethasone dipropionate on your face or scalp?
No — it should not be applied to the face (or groin/underarms), regardless of formulation. The scalp is different: the topical suspension formulation is specifically labeled for scalp psoriasis in appropriate age groups, so a scalp-formulated product can be used there, but always follow the specific product's labeling or your provider's instructions.
How much does Calcipotriene-Betameth Diprop cost without insurance?
The price of Calcipotriene-Betameth Diprop without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 73% off retail prices with a free Rx.com coupon.
What are the common side effects of Calcipotriene-Betameth Diprop?
Common side effects of Calcipotriene-Betameth Diprop may include: Burning, pain, redness, or thinning of the skin, Increased hunger, thirst, or urination, Blurred vision or other change in vision, eye pain, Cold feeling, weakness, tiredness, nausea, vomiting, weight loss, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Calcipotriene-Betameth Diprop?
Generic versions may be available for Calcipotriene-Betameth Diprop. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Calcipotriene-Betameth Diprop on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Calcipotriene-Betameth Diprop?
The cheapest pharmacy for Calcipotriene-Betameth Diprop depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Calcipotriene-Betameth Diprop near you.

Calcipotriene-Betameth Diprop Coupons & Prices

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Calcipotriene and betamethasone dipropionate is a combination topical medicine for plaque psoriasis, and if you're comparing a calcipotriene-betameth-diprop coupon against other savings sites, the most useful thing to know is that this combination is already available as a generic (for the ointment and topical suspension formulations) and that the price for that generic can still vary widely from one pharmacy to the next. Rx.com compares pricing across 60,000+ pharmacies so you can find where it's lowest near you — enter your ZIP above to see today's price.

What is calcipotriene and betamethasone dipropionate?

This medicine combines two active ingredients in one topical product: calcipotriene, a vitamin D analog, and betamethasone dipropionate, a high-potency topical corticosteroid. Together they're FDA-approved to treat plaque psoriasis on the skin. It's sold under a few brand names — Taclonex (ointment and topical suspension, now widely available as a generic), Enstilar (an aerosol foam approved for patients 12 and older), and Wynzora (a newer cream formulation approved for adults 18 and older).

Depending on the formulation, it's applied once daily to the affected skin, generally for a limited course of several weeks before your provider reassesses your skin. It's approved specifically for plaque psoriasis — not for other skin conditions — though a provider may occasionally use it short-term, off-label, for other steroid- and vitamin-D-responsive scaling patches.

Cost and how to save on calcipotriene/betamethasone

Because a generic version of the ointment and topical suspension is now widely available, this combination is a lower-cost option compared to filling a brand-only product — but the cash price for the same generic can still swing noticeably between pharmacies in the same town, which is exactly what a pharmacy comparison tool like Rx.com is built to catch. Enstilar foam and Wynzora cream are newer branded formulations, so if your prescription is written for one of those, pricing works differently than for the generic ointment/suspension.

If cost is a concern, ask your provider or pharmacist whether the generic ointment or suspension is appropriate for your situation, since it's typically the most price-competitive option. The manufacturer of Enstilar and Taclonex, LEO Pharma, also offers a co-pay savings program through its official patient site for eligible commercially-insured patients — terms, eligibility, and savings amounts vary and are set by the manufacturer, so check directly with them for current details. Either way, enter your ZIP above to compare pharmacy prices near you before you fill.

Taclonex vs. Enstilar vs. Wynzora, and other options

All three brand names contain the same two active ingredients, but the formulation changes how and where you use them. Taclonex ointment and topical suspension are the original formulations (suspension for the scalp, ointment for the body) and are the versions with a generic now on the market. Enstilar is an aerosol foam approved for patients 12 and older. Wynzora is a newer cream-based formulation approved for adults. Your provider chooses the formulation based on where the psoriasis is and what's easiest for you to apply consistently.

If this combination isn't the right fit, other topical options your provider might consider include calcipotriene alone, betamethasone dipropionate alone, or another high-potency topical steroid such as clobetasol propionate or triamcinolone acetonide. For more extensive or harder-to-control plaque psoriasis, a provider may move to a systemic option such as methotrexate instead of a topical.

Safety information

As a topical corticosteroid, betamethasone dipropionate can cause local skin thinning, stretch marks, or visible small blood vessels with prolonged use, and using it over large areas, under wraps, or for too long can lead to whole-body steroid absorption, reversible suppression of the body's normal cortisol response, and rarely high blood sugar or Cushing's syndrome. The calcipotriene component carries a separate risk of elevated calcium levels in the blood or urine, particularly if you use more than your product's labeled weekly amount — check your specific product's label or ask your pharmacist what that limit is for your formulation.

  • Do not apply to the face, groin, underarms, or under a bandage/wrap, and avoid getting it in your eyes.
  • If you're using Enstilar foam, it's flammable — stay away from open flame or lit cigarettes until it's dried on your skin.
  • Not for use in the eyes, mouth, or vagina.
  • The most common side effects are irritation, itching, or burning where it's applied.

This product does not carry an FDA boxed warning. This isn't a complete list of risks — talk with your doctor or pharmacist about whether it's right for you and how long to use it.

Sources & accuracy

This Calcipotriene-Betameth Diprop information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Calcipotriene-Betameth Diprop on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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