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Hydrocodone-Acetaminophen

Hydrocodone Acetaminophen

What is Hydrocodone-Acetaminophen?

Hydrocodone-Acetaminophen is a prescription opioid pain medication used to manage moderate to moderately severe pain when other treatments are not sufficient. Combining hydrocodone, an opioid analgesic, with acetaminophen, a non-opioid pain reliever, this medication helps reduce pain and improve comfort for short-term and chronic pain conditions. Learn about Hydrocodone-Acetaminophen uses, dosage, side effects, risks, and important safety information.

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  • Dark urine or pale stools, loss of appetite, nausea or vomiting, stomach pain, yellow skin or eyes
  • Changes in skin color, dark freckles, cold feeling, tiredness, weight loss
  • Blistering, peeling, red skin rash
  • Blue lips, fingernails, or skin
  • Extreme weakness, shallow breathing, slow heartbeat, sweating, seizures, cold or clammy skin
  • Lightheadedness, dizziness, fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, muscle spasms, twitching, diarrhea, seeing or hearing things that are not there
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.
  • This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lung or breathing problems, gallbladder or pancreas problems, an underactive thyroid, adrenal problems, prostate problems, trouble urinating, stomach problems, or a history of head injury or brain tumor, seizures, alcohol or drug addiction.
  • This medicine may cause the following problems: High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Sleep-related breathing problems (including sleep apnea, sleep-related hypoxemia)Adrenal gland problemsLow blood pressureLiver problemsSerious skin reactions (including acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis)SeizuresSerotonin syndrome, when used with certain medicines
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • This medicine may make you dizzy or drowsy. Do not drive or doing anything else that could be dangerous until you know how this medicine affects you.
  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
How much does HYDROcodone-Acetaminophen 5-325MG cost without insurance?
The price of HYDROcodone-Acetaminophen 5-325MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of HYDROcodone-Acetaminophen 5-325MG?
Common side effects of HYDROcodone-Acetaminophen 5-325MG may include: Dark urine or pale stools, loss of appetite, nausea or vomiting, stomach pain, yellow skin or eyes, Changes in skin color, dark freckles, cold feeling, tiredness, weight loss, Blistering, peeling, red skin rash, Blue lips, fingernails, or skin, Extreme weakness, shallow breathing, slow heartbeat, sweating, seizures, cold or clammy skin. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of HYDROcodone-Acetaminophen 5-325MG?
Generic versions may be available for HYDROcodone-Acetaminophen 5-325MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search HYDROcodone-Acetaminophen 5-325MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for HYDROcodone-Acetaminophen 5-325MG?
The cheapest pharmacy for HYDROcodone-Acetaminophen 5-325MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for HYDROcodone-Acetaminophen 5-325MG near you.

Hydrocodone-Acetaminophen Coupons & Prices

Hydrocodone Acetaminophen

What is Hydrocodone-Acetaminophen ?

Hydrocodone-Acetaminophen is a prescription opioid pain medication used to manage moderate to moderately severe pain when other treatments are not sufficient. Combining hydrocodone, an opioid analgesic, with acetaminophen, a non-opioid pain reliever, this medication helps reduce pain and improve comfort for short-term and chronic pain conditions. Learn about Hydrocodone-Acetaminophen uses, dosage, side effects, risks, and important safety information.

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Hydrocodone-Acetaminophen 5mg/325mg (12)
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Hydrocodone-Acetaminophen is a prescription pain medication used to treat moderate to moderately severe pain that cannot be adequately controlled with non-opioid treatments alone. This combination medication contains hydrocodone, an opioid analgesic that affects pain signals in the brain and nervous system, and acetaminophen, a widely used pain reliever and fever reducer. Together, these ingredients provide enhanced pain relief for a variety of medical conditions and injuries.


Hydrocodone-Acetaminophen is commonly prescribed following surgery, dental procedures, injuries, or for certain chronic pain conditions when stronger pain management is necessary. It is available in several strengths and is sold under brand names such as Norco, Vicodin, and Lortab, as well as generic formulations. Because it contains an opioid, Hydrocodone-Acetaminophen is classified as a controlled substance and carries a risk of misuse, dependence, addiction, and overdose.


Common side effects may include drowsiness, dizziness, nausea, vomiting, constipation, headache, and fatigue. More serious risks include slowed breathing, severe sedation, liver damage from excessive acetaminophen use, and opioid dependence. Patients should take Hydrocodone-Acetaminophen exactly as prescribed and avoid combining it with alcohol, sedatives, or other medications that may increase the risk of dangerous side effects.


Many people search for information about Hydrocodone-Acetaminophen dosage, side effects, pain relief effectiveness, drug interactions, withdrawal symptoms, and safety precautions. Understanding how this medication works, its risks, and appropriate use is essential for safe pain management.


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