Levamlodipine Maleate Coupons & Prices

Important update: levamlodipine maleate is no longer marketed in the United States. FDA withdrew approval of the application it was sold under (NDA 212895) effective September 3, 2025, which covers both the former brand Conjupri and the levamlodipine tablets that were distributed as an authorized generic. FDA's notice allowed pharmacies to keep dispensing stock they already had on hand until it ran out or expired, so there is no ongoing supply to price-shop. If you were taking levamlodipine, do not stop your blood pressure medicine on your own. Talk with your prescriber about what to switch to. The closely related medicine amlodipine is still widely available as a generic, and you can use the free Rx.com coupon to compare its cash price at more than 60,000 pharmacies if your prescriber decides it is right for you.

What is levamlodipine maleate and how does it work?

Levamlodipine maleate is a dihydropyridine calcium channel blocker (also called a calcium antagonist). It is the purified S-(-) enantiomer of amlodipine, the half of the amlodipine molecule that carries essentially all of the calcium-channel-blocking activity. By relaxing the muscle in blood vessel walls, it widens the vessels so blood moves through them more easily and blood pressure comes down.

While it was marketed, it was FDA-approved for the treatment of hypertension in adults and pediatric patients 6 years and older, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, mainly strokes and heart attacks. It could be used on its own or alongside other blood pressure medicines. One point worth knowing: unlike racemic amlodipine (Norvasc), the levamlodipine label did not carry the coronary artery disease indications such as chronic stable angina or vasospastic (Prinzmetal) angina.

Levamlodipine maleate is no longer sold in the US: what that means for you

Levamlodipine maleate reached the US market in two forms, and neither is available now. The brand Conjupri (CSPC Ouyi) was approved in December 2019, and a generic-labeled version, levamlodipine tablets from Xspire Pharma, was marketed starting in August 2021 as an NDA authorized generic. An authorized generic is sold under the brand's own application rather than under a separate generic approval, so when FDA withdrew approval of NDA 212895 effective September 3, 2025 at the applicant's request, both the brand and the authorized generic were covered. FDA's withdrawal notice permitted product already in pharmacy inventory on that date to be dispensed until it was depleted or expired.

Because there is no ongoing manufacture or supply, there is no meaningful cash price to compare and no coupon that can restore access to this specific medicine. We would rather tell you that plainly than send you to a pharmacy counter looking for something that is not there.

If you have refills left on a levamlodipine prescription, contact your prescriber or pharmacist rather than waiting for the refill to fail. High blood pressure is treated with a large number of alternatives, and choosing among them depends on your other conditions and medicines. That is a decision for your provider, not a swap to make on your own.

Levamlodipine vs. amlodipine and other blood pressure options

The closest relative is plain amlodipine, usually dispensed as amlodipine besylate and known by the brand Norvasc. Racemic amlodipine is a mixture of two mirror-image forms, only one of which does the work. Levamlodipine was that active form on its own, so roughly 2.5 mg of levamlodipine is about equivalent to 5 mg of racemic amlodipine. The two were never interchangeable at the pharmacy counter, and moving from one to the other requires a new prescription from your provider.

Amlodipine remains widely available as a generic, and its label additionally covers coronary artery disease uses that levamlodipine's did not. Other medicines your prescriber may discuss include the calcium channel blockers nifedipine and felodipine, the ACE inhibitor lisinopril, the ARB losartan, or a combination product such as amlodipine-benazepril. Which one fits you depends on your full medical picture, so bring the question to your provider.

Safety information you should know

Levamlodipine maleate had no boxed warning. It should not be used by anyone with a known hypersensitivity to amlodipine. It can cause symptomatic low blood pressure, particularly in people with severe aortic stenosis. Rarely, people with severe obstructive coronary artery disease may notice more frequent, longer, or more severe angina, or even a heart attack, when starting the drug or after a dose increase. Per the label, small, fragile, or elderly patients, or patients with hepatic insufficiency, may be started on 1.25 mg once daily. It has not been studied in pregnancy-specific trials and human data are limited.

The most common side effects, based largely on amlodipine data, are swelling in the ankles and feet (dose-related), tiredness, dizziness, flushing, palpitations, sleepiness, nausea, and abdominal pain. Levamlodipine is processed by the CYP3A4 enzyme, so CYP3A4 inhibitors such as diltiazem, clarithromycin, or ritonavir can raise its levels and call for closer monitoring. It may also raise exposure to simvastatin (limit simvastatin to 20 mg per day) and to cyclosporine or tacrolimus. Give your pharmacist a full list of everything you take. This information is a summary, not medical advice; talk with your doctor or pharmacist about your own situation.