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Loteprednol Etabonate

Loteprednol Etabonate 5ML of 0.5%

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What is Loteprednol Etabonate?

Loteprednol is an eye medication used to treat various eye conditions, including swelling and pain after cataract surgery, redness and itching from allergies, and dry eye disease. Your doctor will determine the right dose for you.

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What is Loteprednol Etabonate ?

Loteprednol is an eye medication used to treat various eye conditions, including swelling and pain after cataract surgery, redness and itching from allergies, and dry eye disease. Your doctor will determine the right dose for you.

Source: MedlinePlus, U.S. National Library of Medicine

  • Runny nose, sore throat
  • Headache
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, changes in vision, light sensitivity
  • Pain, redness, discharge, swelling, or irritation of the eye
  • Redness, swelling, or irritation of the eye
  • Do not wear contact lenses while you are using Lotemax® or Lotemax® SM.
  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.
  • This medicine may cause the following problems:Eye problems (including glaucoma, cataracts, infections) with long-term useIncreased pressure in your eye, which can damage the optic nerveSlow healing of the eye
  • Tell your doctor if you are pregnant or breastfeeding, or if you have an eye problem (including glaucoma), or if you recently had eye surgery.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is loteprednol etabonate used for?
Loteprednol etabonate is a prescription steroid eye medication used to reduce inflammation in the eye. Depending on the formulation and brand, it treats inflammation and pain after eye surgery (such as cataract surgery), gives temporary relief of seasonal allergic conjunctivitis, and provides short-term treatment (up to two weeks) of the signs and symptoms of dry eye disease. The Lotemax 0.5% suspension is also used for steroid-responsive inflammatory conditions of the conjunctiva, cornea, and front of the eye.
Is loteprednol etabonate the same as Lotemax?
Loteprednol etabonate is the active ingredient, and Lotemax is one of its brand names. Lotemax comes as a 0.5% suspension, gel, and ointment. The same active ingredient is also sold under other brands at different strengths, including Lotemax SM (0.38% gel), Inveltys (1% suspension), Alrex (0.2% suspension), and Eysuvis (0.25% suspension), each approved for specific uses.
Is there a generic version of loteprednol etabonate eye drops?
Yes. An FDA-approved generic loteprednol etabonate is available and is typically lower in cost than the brand-name versions. Prices still vary widely between pharmacies, so it pays to compare. Enter your ZIP above to see today's price near you and print a free Rx.com coupon.
Can loteprednol eye drops raise eye pressure or cause glaucoma?
Yes, it can. Like other eye steroids, prolonged use of loteprednol etabonate can raise the pressure inside the eye and may lead to glaucoma with possible optic nerve damage. It is designed to have a lower impact on eye pressure than some older steroids, but the risk is not zero. If you use it beyond about 10 days, your provider should monitor your intraocular pressure.
How long can you use loteprednol etabonate eye drops?
It depends on the condition and formulation, and you should follow your prescriber's instructions. For dry eye disease, the Eysuvis 0.25% suspension is approved for short-term use of up to two weeks. For other uses, treatment courses vary. If treatment continues beyond about 10 days, your eye pressure should be checked. Do not stop, extend, or change your dose without talking to your eye doctor.
How much does Loteprednol Etabonate cost without insurance?
The price of Loteprednol Etabonate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Loteprednol Etabonate?
Common side effects of Loteprednol Etabonate may include: Runny nose, sore throat, Headache, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blurred vision, changes in vision, light sensitivity, Pain, redness, discharge, swelling, or irritation of the eye. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Loteprednol Etabonate?
Generic versions may be available for Loteprednol Etabonate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Loteprednol Etabonate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Loteprednol Etabonate?
The cheapest pharmacy for Loteprednol Etabonate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Loteprednol Etabonate near you.

Loteprednol Etabonate Coupons & Prices

Loteprednol Etabonate 5ML of 0.5%

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Looking for a loteprednol etabonate coupon? Loteprednol etabonate is a prescription steroid eye medication (the active ingredient in brands like Lotemax, Alrex, Inveltys, and Eysuvis) used to calm eye inflammation. It is available as an FDA-approved generic, which is already lower cost than the brand, but the cash price still varies widely from pharmacy to pharmacy. Enter your ZIP above to compare today's price at pharmacies near you and print a free Rx.com discount coupon in seconds.

What is loteprednol etabonate and how does it work?

Loteprednol etabonate is an ophthalmic corticosteroid, meaning a topical steroid applied directly to the eye. It is a C-20 ester "soft" steroid, designed to reduce inflammation while having a lower impact on intraocular (inside-the-eye) pressure than some older eye steroids. Doctors prescribe it to control swelling, redness, and irritation from several eye conditions.

Depending on the specific formulation and strength, it is FDA-approved to treat inflammation and pain after eye surgery (such as cataract surgery), for temporary relief of seasonal allergic conjunctivitis, and for short-term treatment (up to two weeks) of the signs and symptoms of dry eye disease. The Lotemax 0.5% suspension is also indicated for steroid-responsive inflammatory conditions of the conjunctiva, cornea, and front of the eye. Always use it exactly as your prescriber directs, and shake suspension products before each use.

Cost of loteprednol etabonate without insurance

Because loteprednol etabonate is available as an FDA-approved generic, it is already more affordable than the brand-name versions. Even so, the cash price for the same eye drop can differ a lot between one pharmacy and the next, which is exactly why comparing prices matters. Rx.com checks prices across more than 60,000 pharmacies so you can find the lowest cost near you.

To see what you would pay today with a free Rx.com discount, enter your ZIP code above and select your formulation and quantity. The coupon is free to use whether or not you have insurance, and can often beat an insurance copay on generics. The manufacturer (Bausch + Lomb) also offers brand savings programs through its official Bausch + Lomb Access Program site; those apply to specific brand products, and eligibility and terms vary, so review the details there.

Brand names and related eye medications

Loteprednol etabonate is the generic name behind several brands. These are matched to specific strengths and uses: Lotemax (0.5% suspension, gel, and ointment) and Lotemax SM (0.38% gel) for inflammation and pain after eye surgery; Inveltys (1% suspension) also for post-surgical inflammation; Alrex (0.2% suspension) for seasonal allergic conjunctivitis; and Eysuvis (0.25% suspension) for short-term dry eye disease. Loteprednol is also combined with tobramycin as tobramycin/loteprednol (Zylet) when both an antibiotic and a steroid are needed.

Your eye doctor may consider other steroid-responsive eye treatments depending on your condition, including prednisolone acetate, difluprednate, fluorometholone, and dexamethasone ophthalmic. Each differs in strength, dosing, and effect on eye pressure, so the choice is one to make with your prescriber. You can compare prices on any of these with Rx.com.

Safety and important precautions

Loteprednol etabonate has no boxed warning, but as an eye steroid it does carry risks with prolonged use. These can include elevated eye pressure and glaucoma with possible optic nerve damage, cataract formation (posterior subcapsular), delayed wound healing, and a higher chance of a secondary eye infection (bacterial, fungal, or viral). If you use it beyond about 10 days, your provider should monitor your intraocular pressure. It should not be used in most active viral eye infections (such as herpes simplex or dendritic keratitis), or in fungal or mycobacterial eye infections.

The medication is for use on the surface of the eye only and is never injected into the eye. Avoid letting the bottle tip touch your eye or any surface, since contamination can cause serious eye damage. If you wear soft contact lenses, remove them before instilling the drops and follow your prescriber's guidance on when to reinsert them. This information is educational and not medical advice; talk with your eye doctor or pharmacist about your specific situation.

Sources & accuracy

This Loteprednol Etabonate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Loteprednol Etabonate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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