Olmesartan-Amlodipine-Hctz Coupons & Prices

An olmesartan-amlodipine-HCTZ coupon from Rx.com can lower what you pay at the pharmacy counter for this three-in-one blood pressure tablet, the generic version of Tribenzor. Even though a generic is on the market, the cash price for the same tablet and quantity can differ a lot from one pharmacy to the next, which is exactly why comparing is worth the minute it takes. Rx.com compares prices across more than 60,000 pharmacies, so enter your ZIP above to see today's price near you and bring the free coupon with you. There is no manufacturer savings card for the generic.

What is olmesartan-amlodipine-HCTZ and how does it work?

Olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide is a fixed-dose combination tablet that puts three different blood pressure medicines into one pill. Olmesartan is an angiotensin II receptor blocker (ARB), amlodipine is a dihydropyridine calcium channel blocker, and hydrochlorothiazide (HCTZ) is a thiazide diuretic, or water pill. Because they work in three different ways, they can bring blood pressure down when one or two medicines alone have not been enough.

It is FDA-approved to treat hypertension (high blood pressure) in adults. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, mainly strokes and heart attacks. Importantly, this combination is not meant to be the first blood pressure medicine you try. It is used in people who are not adequately controlled on any two of the three drug classes, or as a substitute for someone already stable on the individual components taken separately. Tablets come in these strengths (amlodipine/HCTZ/olmesartan): 5/12.5/20 mg, 5/12.5/40 mg, 5/25/40 mg, 10/12.5/40 mg, and 10/25/40 mg.

Cost and coupon savings without insurance

If you are paying cash, the honest picture is this: a generic of this exact combination is available in the US, and generics generally cost less than the brand, but the actual price you are quoted still swings widely from pharmacy to pharmacy, even between two stores on the same street. Pharmacies set their own cash prices, so the only reliable way to know what you will pay is to check prices for your exact strength and quantity in your own ZIP code.

That is what an Rx.com coupon is for. It is free, there is no membership required, and it works as a cash-discount price at the counter rather than as insurance. Enter your ZIP above to compare today's prices across more than 60,000 pharmacies, then show the coupon to the pharmacist. If you have insurance, it is still worth comparing, because a cash-coupon price is sometimes lower than a copay. There is no manufacturer savings card for this generic; if you are filling brand-name Tribenzor, check the manufacturer's official website for any current program, since terms vary.

Tribenzor, the individual components, and similar combinations

The brand name for this combination is Tribenzor. The generic contains the same three active ingredients and is prescribed the same way, so ask your pharmacist to price both. You can also compare the pieces on their own: olmesartan (sold as Benicar), amlodipine, and hydrochlorothiazide. Some people take the three separately; a fixed-dose tablet mainly reduces the number of pills.

Two-drug combinations built from the same pieces include olmesartan-HCTZ and amlodipine-olmesartan. Other ARB-based combinations your prescriber might consider include losartan-HCTZ, valsartan-amlodipine-HCTZ, and telmisartan-amlodipine. Which one fits depends on your blood pressure, your kidney function, and what you already tolerate well, so this is a conversation for your doctor rather than a swap to make on your own.

Safety information you should know

This medicine carries a boxed warning for fetal toxicity: drugs that act directly on the renin-angiotensin system can cause injury and death to a developing baby. It should be stopped as soon as possible when pregnancy is detected. Tell your prescriber right away if you are pregnant or planning to become pregnant.

Other important points from the label: blood pressure can drop too low in people who are low on fluids or salt, so that should be corrected before starting. Kidney function can worsen, especially with the diuretic component, and potassium can rise too high (be careful with potassium supplements, potassium-sparing diuretics, and salt substitutes; do not take with aliskiren if you have diabetes, and avoid combining with ACE inhibitors or other ARBs). Some people, particularly with severe obstructive coronary artery disease, have had increased angina or a heart attack when the amlodipine dose is started or raised. Olmesartan has been linked to sprue-like enteropathy, a severe long-lasting diarrhea with major weight loss that can begin months or even years after starting. The HCTZ component can shift electrolytes and metabolic labs (low potassium, sodium, or magnesium; high calcium; high uric acid or gout; higher blood sugar, cholesterol, and triglycerides), and rarely can cause acute angle-closure glaucoma with sudden nearsightedness within hours to weeks of starting, acute respiratory problems including ARDS, lupus flares, or photosensitivity. It is contraindicated in anuria (making no urine) and in people allergic to sulfonamide-derived drugs, and is not recommended if kidney function is severely reduced (CrCl below 30 mL/min). Swelling in the feet and ankles, dizziness, and headache are common. This page is not medical advice; talk with your doctor or pharmacist about your own situation.