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Repatha Sureclick Pen — prescription drug image

Repatha Sureclick

Repatha SureClick 1ML of 140MG/ML

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What is Repatha Sureclick?

Repatha (evolocumab) is a prescription biologic injection used to lower LDL ("bad") cholesterol in adults with high cholesterol or established cardiovascular disease. It belongs to a class called PCSK9 inhibitors — a breakthrough for people who cannot reach their LDL goals with statins alone or who cannot tolerate statins. Repatha SureClick is administered as a self-injection under the skin once monthly (420 mg) or every two weeks (140 mg). Clinical trials have shown it reduces LDL cholesterol by 60% or more and lowers the risk of heart attack and stroke. A cardiologist or primary care provider can determine if Repatha is appropriate for you. With Rx.com, you can compare costs and find the best coupon to reduce your out-of-pocket expenses.

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  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Tell your doctor if you are pregnant or breastfeeding, or if you have a latex allergy.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
How much does Repatha Sureclick cost without insurance?
The price of Repatha Sureclick without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Repatha Sureclick?
Common side effects of Repatha Sureclick may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Repatha Sureclick?
Generic versions may be available for Repatha Sureclick. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Repatha Sureclick on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Repatha Sureclick?
The cheapest pharmacy for Repatha Sureclick depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Repatha Sureclick near you.

Repatha Sureclick Coupons & Prices

Repatha SureClick 1ML of 140MG/ML

What is Repatha Sureclick ?

Repatha (evolocumab) is a prescription biologic injection used to lower LDL ("bad") cholesterol in adults with high cholesterol or established cardiovascular disease. It belongs to a class called PCSK9 inhibitors — a breakthrough for people who cannot reach their LDL goals with statins alone or who cannot tolerate statins. Repatha SureClick is administered as a self-injection under the skin once monthly (420 mg) or every two weeks (140 mg). Clinical trials have shown it reduces LDL cholesterol by 60% or more and lowers the risk of heart attack and stroke. A cardiologist or primary care provider can determine if Repatha is appropriate for you. With Rx.com, you can compare costs and find the best coupon to reduce your out-of-pocket expenses.
Prescriptions & Refills
Compare 60,000+ US pharmacies · save up to 90%
Repatha Sureclick Pen — prescription drug image
Prescription
Repatha Sureclick 1ml of 140mg/ml (8)
43215 ·
43215 Change ZIP

What Is Repatha (Evolocumab)?

Repatha is a brand-name PCSK9 inhibitor biologic (evolocumab) that dramatically lowers LDL cholesterol. It is FDA-approved for adults with heterozygous or homozygous familial hypercholesterolemia (FH), established cardiovascular disease (atherosclerotic CVD), and for adults with primary hyperlipidemia who cannot reach target LDL levels on statins.

How Does Repatha Work?

PCSK9 is a protein in the liver that destroys LDL receptors — the receptors responsible for clearing LDL cholesterol from the blood. By blocking PCSK9, Repatha preserves more LDL receptors on liver cells, allowing them to remove more LDL from the bloodstream. In clinical trials (FOURIER study), Repatha reduced LDL by an average of 59% and cut the risk of heart attack by 27% in high-risk patients.

Dosage and Administration

Repatha SureClick is a prefilled autoinjector for subcutaneous injection:

  • 140 mg every 2 weeks, or
  • 420 mg once monthly (three 140 mg injections given consecutively over 30 minutes)

Injections go into the abdomen, thigh, or upper arm. The SureClick device is designed for self-injection at home after training — no clinic visit needed for ongoing dosing.

Who Should Consider Repatha?

  • Adults with LDL ≥ 70 mg/dL despite maximum tolerated statin therapy
  • Patients with established heart disease who need additional LDL lowering
  • Adults with familial hypercholesterolemia (inherited high cholesterol)
  • Statin-intolerant patients who need significant LDL reduction

Side Effects

Repatha is generally well tolerated. The most common side effects are mild injection site reactions (redness, bruising, pain), upper respiratory infections, and flu-like symptoms.

Cost and Savings

Repatha can be expensive without insurance, but Amgen offers a patient savings program. Use Rx.com to find the best available price in your area and access copay assistance.

Talk to a Provider About Your Cholesterol

If statins are not enough or you cannot tolerate them, Repatha may be an option worth discussing. See a licensed provider on Rx.com to review your lipid panel and determine whether Repatha is right for you.

→ See a Provider Online for High Cholesterol

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