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Trulicity 0.5Ml Pen — prescription drug image

Trulicity

Trulicity

Prescription weight loss

Weight-loss medication, prescribed online

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%

Licensed U.S. providers · No insurance needed · Shipped to your door

See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

What is Trulicity?

Trulicity (dulaglutide) is a prescription GLP-1 receptor agonist used to improve blood sugar control in adults with type 2 diabetes. This once-weekly injectable medication helps the body release insulin when blood sugar levels are elevated, slows digestion, and may support weight management in some patients. Trulicity is also prescribed to help reduce the risk of major cardiovascular events in certain adults with type 2 diabetes and heart disease risk factors. Learn about Trulicity uses, dosage, side effects, weight loss potential, cost, and how it compares to other GLP-1 medications.

Prescription savings · · · ·

What is Trulicity ?

Trulicity (dulaglutide) is a prescription GLP-1 receptor agonist used to improve blood sugar control in adults with type 2 diabetes. This once-weekly injectable medication helps the body release insulin when blood sugar levels are elevated, slows digestion, and may support weight management in some patients. Trulicity is also prescribed to help reduce the risk of major cardiovascular events in certain adults with type 2 diabetes and heart disease risk factors. Learn about Trulicity uses, dosage, side effects, weight loss potential, cost, and how it compares to other GLP-1 medications.

  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
  • Change in how much or how often you urinate, lower back or side pain, blood in your urine
  • Diarrhea, dry mouth, sunken eyes, thirst, wrinkled skin
  • Sudden and severe stomach pain, nausea, vomiting, fever, passing gas, stomach upset or bloating, yellow eyes or skin
  • Lump or swelling in your neck, trouble breathing or swallowing
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, changes in vision
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or a history of diabetic retinopathy or pancreas problems. Tell your doctor if you have severe digestion problems (including gastroparesis) or stomach or bowel problems.
  • This medicine may cause the following problems:Increased risk of thyroid tumorPancreatitis (swelling of the pancreas)Low blood sugar (more likely if you also take insulin or other diabetes medicine)Kidney problemsEye or vision problems, including diabetic retinopathyGallbladder problems, including cholelithiasis, cholecystitis
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness
What is Trulicity used for?
Trulicity (dulaglutide) is FDA-approved, along with diet and exercise, to improve blood sugar control in adults and children 10 years and older with type 2 diabetes. In adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors, it is also approved to reduce the risk of major cardiovascular events such as heart attack, stroke, and cardiovascular death. It is not used for type 1 diabetes.
How much does Trulicity cost without insurance?
Trulicity is a brand-name drug with no generic, so the cash price can be high, and it changes over time and by pharmacy. Rather than quote a figure that may be out of date, enter your ZIP code above to see today's Rx.com cash price at pharmacies near you. If you have commercial insurance, you can also check the manufacturer savings card at trulicity.lilly.com/savings-resources, where terms vary.
Is there a generic version of Trulicity?
No. There is currently no generic version of Trulicity (dulaglutide) available. Because only the brand is on the market, comparing the Rx.com cash coupon price with the manufacturer savings card is one of the best ways to lower your out-of-pocket cost.
What are the most common side effects of Trulicity?
The most common side effects are nausea, diarrhea, vomiting, abdominal pain, decreased appetite, indigestion, and fatigue. More serious risks include a boxed warning about thyroid C-cell tumors, along with pancreatitis, low blood sugar, kidney injury, and gallbladder problems. Discuss any side effects with your doctor or pharmacist.
Does Trulicity cause weight loss?
Trulicity can reduce appetite and may lead to some weight loss, and it is sometimes used off-label for weight management. However, it is not FDA-approved for weight loss; it is approved for type 2 diabetes and, in certain patients, for reducing cardiovascular risk. Talk to your provider about the right medication for your goals.
How much does Trulicity cost without insurance?
The price of Trulicity without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 27% off retail prices with a free Rx.com coupon.
What are the common side effects of Trulicity?
Common side effects of Trulicity may include: Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion, Change in how much or how often you urinate, lower back or side pain, blood in your urine, Diarrhea, dry mouth, sunken eyes, thirst, wrinkled skin, Sudden and severe stomach pain, nausea, vomiting, fever, passing gas, stomach upset or bloating, yellow eyes or skin, Lump or swelling in your neck, trouble breathing or swallowing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Trulicity?
Generic versions may be available for Trulicity. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Trulicity on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Trulicity?
The cheapest pharmacy for Trulicity depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Trulicity near you.

Trulicity Coupons & Prices

Trulicity

Prescription weight loss

Weight-loss medication, prescribed online

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%

Licensed U.S. providers · No insurance needed · Shipped to your door

See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.
Trulicity 0.5Ml Pen — prescription drug image
Prescription
Trulicity 1.5mg/0.5ml (4)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Trulicity coupon? Trulicity (dulaglutide) is a brand-name, once-weekly injection used with diet and exercise to improve blood sugar control in type 2 diabetes and, in certain patients, to lower the risk of heart attack and stroke. It is not yet available as a generic, so the price can be high without help. Enter your ZIP code above to see today's Rx.com cash price at pharmacies near you, and compare it with the manufacturer savings card to find your lowest out-of-pocket cost.

What is Trulicity and how does it work?

Trulicity is the brand name for dulaglutide, a medicine in the GLP-1 receptor agonist class (also called an incretin mimetic). It is FDA-approved as an add-on to diet and exercise to improve glycemic control in adults and in children 10 years and older with type 2 diabetes. In adults with type 2 diabetes who already have cardiovascular disease or several cardiovascular risk factors, it is also approved to reduce the risk of major cardiovascular events such as heart attack, stroke, and cardiovascular death.

It is given as a once-weekly injection under the skin. Trulicity is not indicated for type 1 diabetes. Because GLP-1 medicines can reduce appetite and lead to some weight loss, Trulicity is sometimes used off-label for weight management, but it is not FDA-approved for weight loss.

Trulicity cost and savings: manufacturer card vs. Rx.com cash coupon

Two different discounts can lower the cost of Trulicity, and it helps to understand the difference. The manufacturer savings card from Lilly is generally for people with commercial (private) insurance and is usually not available to those on Medicare, Medicaid, or other government programs. Terms and eligibility vary, so check the official page at trulicity.lilly.com/savings-resources for current details.

The Rx.com cash coupon works differently: it is a cash-price discount that does not use insurance at all. That makes it useful if you are uninsured, if you are on Medicare and cannot use the manufacturer card, or if your pharmacy declines the card for any reason. There is no generic version of Trulicity available yet, so comparing the cash coupon price against the savings card is one of the best ways to find your lowest cost. Enter your ZIP above to see today's price at pharmacies near you.

Trulicity alternatives and related medications

Trulicity is one of several GLP-1 and related injectable or oral diabetes medicines. If you and your provider are weighing options, other drugs in or near this class include Ozempic, Mounjaro, Victoza, and the oral GLP-1 pill Rybelsus. For weight management specifically, Wegovy is an FDA-approved option, whereas Trulicity is approved for type 2 diabetes and cardiovascular risk reduction.

These medicines differ in their exact approved uses, dosing, and how they are taken, so the right choice depends on your health history and goals. Only your prescriber can decide which medication is appropriate for you. You can look up the current cash price for any of these on Rx.com by entering your ZIP.

Trulicity safety and side effects

Trulicity carries a boxed warning about the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), based on rodent studies. It should not be used by people with a personal or family history of MTC or with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Other serious risks include acute pancreatitis, low blood sugar (especially when taken with insulin or a sulfonylurea), acute kidney injury (often from dehydration caused by nausea, vomiting, or diarrhea), gallbladder disease, serious allergic reactions, worsening of diabetic eye disease, and reports of intestinal blockage (ileus).

The most common side effects are nausea, diarrhea, vomiting, abdominal pain, decreased appetite, indigestion, and fatigue. This is a summary, not medical advice. Talk with your doctor or pharmacist about your full medical history and any medicines you take before starting or changing Trulicity.

Sources & accuracy

This Trulicity information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Trulicity on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Trulicity — Articles & Guides

6 articles
Buy Semaglutide Online: The Weight-Loss Injection Explained
Buy Semaglutide Online: The Weight-Loss Injection Explained
Looking for an affordable weight-loss shot? This guide shows exactly how to buy semaglutide online for as little as $149 a month through Rx.com, compare prices at U.S. pharmacies, and decide if it’s right for you.
GLP-1 Drugs Compared: Ozempic®, Wegovy®, Trulicity®, Victoza®, and Mounjaro®
GLP-1 Drugs Compared: Ozempic®, Wegovy®, Trulicity®, Victoza®, and Mounjaro®
Wondering which GLP-1 medication is right for you? This deep-dive compares Ozempic, Wegovy, Trulicity, Victoza, Mounjaro, and more on effectiveness, safety, and real-world costs so you can discuss the best option with your doctor.
How to Get a Xarelto Prescription Online
How to Get a Xarelto Prescription Online
Getting a Xarelto prescription or refill no longer requires an in-person visit. Licensed providers can evaluate you online and send the prescription directly to your pharmacy. This guide covers the process, costs, and how to save with a free Rx.com coupon.
Is glp1 the same as Ozempic
Is glp1 the same as Ozempic
GLP-1 is a naturally occurring gut hormone, while Ozempic is a brand-name semaglutide injection that mimics GLP-1. Learn how they differ, when each is used, and ways to pay 53–87% less at the pharmacy with Rx.com.
How to Get a Trulicity Prescription Online for Type 2 Diabetes
How to Get a Trulicity Prescription Online for Type 2 Diabetes
Trulicity (dulaglutide) is a once-weekly GLP-1 receptor agonist injection for Type 2 diabetes. Licensed providers can prescribe or refill it through a telehealth visit, with the prescription sent straight to your pharmacy.
How to Get a Toujeo SoloStar Prescription Online
How to Get a Toujeo SoloStar Prescription Online
Toujeo SoloStar is a concentrated long-acting insulin used to manage Type 2 and Type 1 diabetes. Licensed providers can evaluate and prescribe it through telehealth, with the prescription sent directly to your pharmacy.
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