Trulicity
Trulicity
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
What is Trulicity?
Trulicity (dulaglutide) is a prescription GLP-1 receptor agonist used to improve blood sugar control in adults with type 2 diabetes. This once-weekly injectable medication helps the body release insulin when blood sugar levels are elevated, slows digestion, and may support weight management in some patients. Trulicity is also prescribed to help reduce the risk of major cardiovascular events in certain adults with type 2 diabetes and heart disease risk factors. Learn about Trulicity uses, dosage, side effects, weight loss potential, cost, and how it compares to other GLP-1 medications.
Side Effects
- Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
- Change in how much or how often you urinate, lower back or side pain, blood in your urine
- Diarrhea, dry mouth, sunken eyes, thirst, wrinkled skin
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or a history of diabetic retinopathy or pancreas problems. Tell your doctor if you have severe digestion problems (including gastroparesis) or stomach or bowel problems.
- This medicine may cause the following problems:Increased risk of thyroid tumorPancreatitis (swelling of the pancreas)Low blood sugar (more likely if you also take insulin or other diabetes medicine)Kidney problemsEye or vision problems, including diabetic retinopathyGallbladder problems, including cholelithiasis, cholecystitis
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness
Prescription savings · · · ·
What is Trulicity ?
Trulicity (dulaglutide) is a prescription GLP-1 receptor agonist used to improve blood sugar control in adults with type 2 diabetes. This once-weekly injectable medication helps the body release insulin when blood sugar levels are elevated, slows digestion, and may support weight management in some patients. Trulicity is also prescribed to help reduce the risk of major cardiovascular events in certain adults with type 2 diabetes and heart disease risk factors. Learn about Trulicity uses, dosage, side effects, weight loss potential, cost, and how it compares to other GLP-1 medications.
- Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
- Change in how much or how often you urinate, lower back or side pain, blood in your urine
- Diarrhea, dry mouth, sunken eyes, thirst, wrinkled skin
- Sudden and severe stomach pain, nausea, vomiting, fever, passing gas, stomach upset or bloating, yellow eyes or skin
- Lump or swelling in your neck, trouble breathing or swallowing
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision, changes in vision
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or a history of diabetic retinopathy or pancreas problems. Tell your doctor if you have severe digestion problems (including gastroparesis) or stomach or bowel problems.
- This medicine may cause the following problems:Increased risk of thyroid tumorPancreatitis (swelling of the pancreas)Low blood sugar (more likely if you also take insulin or other diabetes medicine)Kidney problemsEye or vision problems, including diabetic retinopathyGallbladder problems, including cholelithiasis, cholecystitis
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness
Trulicity Coupons & Prices
Trulicity
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Trulicity coupon? Trulicity (dulaglutide) is a brand-name, once-weekly injection used with diet and exercise to improve blood sugar control in type 2 diabetes and, in certain patients, to lower the risk of heart attack and stroke. It is not yet available as a generic, so the price can be high without help. Enter your ZIP code above to see today's Rx.com cash price at pharmacies near you, and compare it with the manufacturer savings card to find your lowest out-of-pocket cost.
What is Trulicity and how does it work?
Trulicity is the brand name for dulaglutide, a medicine in the GLP-1 receptor agonist class (also called an incretin mimetic). It is FDA-approved as an add-on to diet and exercise to improve glycemic control in adults and in children 10 years and older with type 2 diabetes. In adults with type 2 diabetes who already have cardiovascular disease or several cardiovascular risk factors, it is also approved to reduce the risk of major cardiovascular events such as heart attack, stroke, and cardiovascular death.
It is given as a once-weekly injection under the skin. Trulicity is not indicated for type 1 diabetes. Because GLP-1 medicines can reduce appetite and lead to some weight loss, Trulicity is sometimes used off-label for weight management, but it is not FDA-approved for weight loss.
Trulicity cost and savings: manufacturer card vs. Rx.com cash coupon
Two different discounts can lower the cost of Trulicity, and it helps to understand the difference. The manufacturer savings card from Lilly is generally for people with commercial (private) insurance and is usually not available to those on Medicare, Medicaid, or other government programs. Terms and eligibility vary, so check the official page at trulicity.lilly.com/savings-resources for current details.
The Rx.com cash coupon works differently: it is a cash-price discount that does not use insurance at all. That makes it useful if you are uninsured, if you are on Medicare and cannot use the manufacturer card, or if your pharmacy declines the card for any reason. There is no generic version of Trulicity available yet, so comparing the cash coupon price against the savings card is one of the best ways to find your lowest cost. Enter your ZIP above to see today's price at pharmacies near you.
Trulicity alternatives and related medications
Trulicity is one of several GLP-1 and related injectable or oral diabetes medicines. If you and your provider are weighing options, other drugs in or near this class include Ozempic, Mounjaro, Victoza, and the oral GLP-1 pill Rybelsus. For weight management specifically, Wegovy is an FDA-approved option, whereas Trulicity is approved for type 2 diabetes and cardiovascular risk reduction.
These medicines differ in their exact approved uses, dosing, and how they are taken, so the right choice depends on your health history and goals. Only your prescriber can decide which medication is appropriate for you. You can look up the current cash price for any of these on Rx.com by entering your ZIP.
Trulicity safety and side effects
Trulicity carries a boxed warning about the risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), based on rodent studies. It should not be used by people with a personal or family history of MTC or with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Other serious risks include acute pancreatitis, low blood sugar (especially when taken with insulin or a sulfonylurea), acute kidney injury (often from dehydration caused by nausea, vomiting, or diarrhea), gallbladder disease, serious allergic reactions, worsening of diabetic eye disease, and reports of intestinal blockage (ileus).
The most common side effects are nausea, diarrhea, vomiting, abdominal pain, decreased appetite, indigestion, and fatigue. This is a summary, not medical advice. Talk with your doctor or pharmacist about your full medical history and any medicines you take before starting or changing Trulicity.
This Trulicity information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Trulicity on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.