TB-500

Thymosin Beta-4 fragment · TB4

Also known as half of the "Wolverine stack"

A synthetic version of a natural repair peptide studied for recovery and flexibility.

Not yet available

Pending FDA approval

Coming Soon Once TB-500 is FDA approved, you’ll be able to get a prescription and compare prices here on Rx.com. Browse available medications →

TB-500 is a synthetic peptide based on a region of a naturally occurring protein called Thymosin Beta-4, which is found in nearly every cell in the body and plays a role in cell movement and repair. TB-500 is widely discussed in athletic and veterinary recovery circles for tissue healing and flexibility. Like the other peptides here, TB-500 is investigational — it is not FDA approved and is not sold or prescribed through Rx.com.

What TB-500 is being researched for

People most often look into TB-500 in connection with the areas below. These are research directions — not approved or proven treatments.

Muscle, tendon & ligament recovery
Flexibility and range of motion
Wound and soft-tissue healing
Exercise-related inflammation
Endurance and overall recovery

What is TB-500?

TB-500 is a lab-made fragment that mimics the active, repair-related region of Thymosin Beta-4. The natural protein helps cells build the internal "scaffolding" (actin) they need to move, which matters a great deal during healing when cells travel to an injured site. Researchers study TB-500 to see whether delivering that active region can support faster, more organized repair.

How is TB-500 thought to work?

In preclinical research, TB-500 is described as promoting cell migration and new blood-vessel growth, both of which are central to healing damaged tissue. It is also studied for effects on flexibility and inflammation. As with the other peptides on this page, the strongest evidence is from laboratory and animal models, so human benefits are not established.

What is TB-500 being researched for?

Interest centers on recovery from soft-tissue injuries, tendon and muscle repair, flexibility, and wound healing. It is often mentioned in the same conversations as BPC-157 for recovery "stacks." Note that TB-500 is banned in most competitive sports and is not an approved human medicine. Rx.com lists it here for education only.

Is TB-500 FDA approved or available?

No. TB-500 is not FDA approved for human use and is not available to purchase or be prescribed through Rx.com. If a related, approved therapy becomes available, Rx.com plans to help eligible patients compare prices and access it safely.

Frequently asked questions

Why is TB-500 part of the "Wolverine stack"?

TB-500 is best known as the partner to BPC-157 in the so-called "Wolverine stack," a recovery pairing named after the Marvel character famous for healing quickly. The two are often researched together because BPC-157 is studied for creating the conditions for healing while TB-500 is studied for helping cells migrate to repair tissue. The nickname is informal and neither peptide is FDA approved.

Can I get TB-500 through Rx.com?

No. TB-500 is not FDA approved and is not available through Rx.com. This page is educational only.

What is TB-500 used for?

It is researched for tissue repair, recovery, and flexibility. These uses are investigational and not FDA approved.

Is TB-500 the same as BPC-157?

No. They are different peptides, though both are studied for recovery and are sometimes discussed together. Neither is FDA approved.

Is TB-500 allowed in sports?

No. TB-500 is prohibited by most anti-doping organizations. It is not an approved human medicine.

Medical disclaimer: The information on this page is provided for general educational purposes only and is not medical advice. This peptide is not approved by the U.S. Food and Drug Administration (FDA) and is not currently available to purchase or be prescribed through Rx.com. Statements here have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Always talk to a licensed healthcare professional before considering any new therapy.