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Fluticasone Propionate Hfa Inhaler — prescription drug image

Fluticasone Propionate Hfa

Fluticasone Propionate HFA 12GM of 110MCG/ACT

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What is Fluticasone Propionate Hfa?

Fluticasone Propionate HFA is an aerosol medication used to help manage breathing problems caused by asthma and chronic obstructive pulmonary disease (COPD). It works by reducing inflammation in the airways, making it easier to breathe.

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What is Fluticasone Propionate Hfa ?

Fluticasone Propionate HFA is an aerosol medication used to help manage breathing problems caused by asthma and chronic obstructive pulmonary disease (COPD). It works by reducing inflammation in the airways, making it easier to breathe.

Source: MedlinePlus, U.S. National Library of Medicine

  • Color changes on the skin, dark freckles, easy bruising, muscle weakness, round or puffy face
  • Tiredness, weakness, nausea and vomiting, dizziness
  • Bone pain or fractures
  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Eye pain or vision changes
  • Worsening of breathing problems
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, osteoporosis, cataracts, or glaucoma. Tell your doctor if you have any immune system problems or infections, including herpes simplex in your eye or tuberculosis. Tell your doctor right away if you are exposed to measles or chickenpox.
  • This medicine may cause the following problems:Increased trouble breathing right after use (paradoxical bronchospasm), which can be life-threateningLow bone mineral density, which may lead to osteoporosisCataracts, glaucoma, or other vision problemsSlow growth in childrenProblems with the adrenal glandsHigher risk of infection, including fungus infection in the mouth (thrush)
  • This medicine will not stop an asthma attack that has already started. You should have another medicine to use in case of an acute asthma attack.
  • Inhalation routeIf any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
  • Tell any doctor or dentist who treats you that you are using this medicine.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • You may need to use this medicine for 1 to 2 weeks before your asthma starts to get better. Call your doctor if your symptoms do not improve or if they get worse.
Is fluticasone propionate HFA the same as Flovent HFA?
Essentially, yes. Flovent HFA was the brand name, and GSK discontinued it in January 2024. What you get now is fluticasone propionate HFA inhalation aerosol: either the authorized generic, which is made by GSK and distributed by Prasco and comes in 44, 110 and 220 mcg per actuation, or the FDA-approved generic from Glenmark, which the FDA approved in March 2026 as the first generic of Flovent HFA and which is made in 44 mcg per actuation only. Both contain the same active ingredient as the old brand. If your prescription is for 110 mcg or 220 mcg, only the Prasco/GSK authorized generic is available in that strength.
How long does fluticasone propionate HFA take to work for asthma?
It is a daily controller, not a quick-relief medicine, so it works gradually. Many people notice improvement within the first day or two of regular use, but the label notes that maximum benefit may not be reached for one to two weeks or longer of consistent twice-daily dosing. Keep using it every day even when you feel fine, and check with your prescriber if you are not improving.
Can fluticasone propionate HFA be used as a rescue inhaler?
No. The FDA label is explicit that it is not indicated for relief of acute bronchospasm and should not be used for an asthma attack or status asthmaticus. It will not open your airways quickly. You still need a separate short-acting rescue inhaler, such as albuterol, and you should tell your prescriber if you are needing it more often than usual.
Why do you have to rinse your mouth after using fluticasone propionate HFA?
Some of the steroid settles in the mouth and throat instead of reaching the lungs. That leftover medicine can allow a Candida albicans (yeast) infection to grow, causing oral thrush, and it can also lead to hoarseness. Rinsing with water and spitting it out, without swallowing, after each use washes it away and lowers those risks.
What are the differences between the 44 mcg, 110 mcg and 220 mcg strengths?
They are the same medicine, just different amounts of fluticasone propionate delivered per puff. On the FDA label, the starting dosage for patients aged 12 and older who are not already taking an inhaled corticosteroid is 88 mcg twice daily, which is two puffs of the 44 mcg strength, and children 4 to 11 years old take 88 mcg twice daily. The label says the starting dosage depends on previous asthma therapy and asthma severity, and that a higher dosage may be needed if asthma is not adequately controlled after about two weeks; the labeled maximum for patients 12 and older is 880 mcg twice daily. The higher-strength inhalers are a way to deliver those larger daily amounts in fewer puffs. Only your prescriber should decide which strength and how many puffs are right for you.
How much does Fluticasone Propionate Hfa cost without insurance?
The price of Fluticasone Propionate Hfa without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Fluticasone Propionate Hfa?
Common side effects of Fluticasone Propionate Hfa may include: Color changes on the skin, dark freckles, easy bruising, muscle weakness, round or puffy face, Tiredness, weakness, nausea and vomiting, dizziness, Bone pain or fractures, Fever, chills, cough, runny or stuffy nose, sore throat, body aches, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fluticasone Propionate Hfa?
Generic versions may be available for Fluticasone Propionate Hfa. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fluticasone Propionate Hfa on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fluticasone Propionate Hfa?
The cheapest pharmacy for Fluticasone Propionate Hfa depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fluticasone Propionate Hfa near you.

Fluticasone Propionate Hfa Coupons & Prices

Fluticasone Propionate HFA 12GM of 110MCG/ACT

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Use a free fluticasone propionate HFA coupon from Rx.com to compare cash prices on this inhaled corticosteroid (ICS) maintenance inhaler for asthma. Fluticasone propionate HFA inhalation aerosol is the generic version of Flovent HFA, which GSK discontinued in January 2024. Two different products carry the name today: a GSK-manufactured authorized generic distributed by Prasco, available in 44 mcg, 110 mcg and 220 mcg per actuation, and an FDA-approved generic from Glenmark, which the FDA approved in March 2026 as the first generic of Flovent HFA and which comes in 44 mcg per actuation only. Cash prices swing a lot from one pharmacy to the next, so compare before you fill. Enter your ZIP code above to see today's price near you and print, text or show your coupon at the counter.

What is fluticasone propionate HFA and how does it work?

Fluticasone propionate HFA is a metered-dose inhaler that delivers a synthetic trifluorinated glucocorticoid (a corticosteroid) straight into the lungs. It belongs to the drug class known as inhaled corticosteroids, or ICS. It is FDA-approved as maintenance, or "controller," treatment of asthma as prophylactic therapy in adults and children 4 years and older. Taken every day, it calms the ongoing swelling and irritation inside the airways so that flare-ups happen less often and breathing stays steadier over time.

This is not a fast-acting inhaler. It is not indicated for relief of acute bronchospasm, so anyone using it still needs a separate rescue inhaler, such as albuterol, for sudden symptoms. On dosing, the FDA label says the starting dosage for patients aged 12 and older who are not already on an inhaled corticosteroid is 88 mcg (two inhalations of the 44 mcg strength) twice daily, and that children 4 to 11 years old take 88 mcg twice daily. The label does not set one fixed dose for everyone: it states that the starting dosage is based on previous asthma therapy and asthma severity, and that a higher dosage may provide additional asthma control for other patients and for people who do not respond adequately after about two weeks. The labeled maximum for patients 12 and older is 880 mcg twice daily. Your prescriber sets the strength and the number of puffs, so follow the directions on your label rather than adjusting on your own.

Fluticasone propionate HFA cost and coupon savings without insurance

Do not assume the generic is automatically the cheaper option. When GSK pulled brand Flovent HFA, a Senate investigation and an analysis by health economists at Johns Hopkins found that the authorized generic's average net price to insurers ran materially higher than the brand had been, and many families ended up paying more after the switch. What that means for you at the counter is simple: prices vary by pharmacy, and you should compare before you fill. Cash prices for the identical inhaler and strength can differ substantially between a chain drugstore, a grocery-store pharmacy and an independent down the street. Rx.com compares prices across more than 60,000 participating pharmacies so you can see who is cheapest near you today.

There is no manufacturer savings card for this generic. Prasco, which distributes the GSK-made authorized generic, runs a patient assistance program described on its own official website; eligibility and terms vary and can change, so verify directly with the manufacturer if paying cash is a hardship. Glenmark's pricing and any copay support for its 44 mcg generic can likewise change, so check current terms rather than relying on what you were told at a past fill. To use an Rx.com coupon, enter your ZIP code above, pick the strength your prescriber wrote for, then show the coupon at the pharmacy counter. It is free, requires no membership, and can be used whether or not you have insurance, though you cannot combine it with an insurance benefit on the same fill. Some people find the coupon price beats their copay, so it is worth asking the pharmacist to run both.

Alternatives and related asthma inhalers

Fluticasone propionate HFA is a single-ingredient steroid inhaler. Some people need a combination inhaler that pairs a steroid with a long-acting bronchodilator, and some do better on a once-daily dry-powder steroid. Related options your prescriber may discuss include:

  • Arnuity Ellipta — a once-daily dry-powder inhaler containing fluticasone furoate (a different fluticasone ester, not the same molecule as fluticasone propionate).
  • Advair Diskus — fluticasone propionate combined with the long-acting beta-agonist salmeterol, in a dry-powder device.
  • Symbicort — budesonide plus formoterol, another inhaled-steroid-and-bronchodilator combination.
  • Albuterol — a short-acting rescue inhaler, used for sudden symptoms alongside (not instead of) a daily controller.

Note that GSK discontinued both Flovent HFA and Flovent Diskus in January 2024, so those brands are no longer marketed in the US; fluticasone propionate HFA inhalation aerosol is the direct replacement for Flovent HFA. If you were prescribed the 110 mcg or 220 mcg strength, that is currently the Prasco/GSK authorized generic, because Glenmark's FDA-approved generic is made only in 44 mcg per actuation. Switching between inhalers is not a like-for-like swap, because devices, doses and ingredients differ, so never change on your own. Talk with your prescriber or pharmacist first.

Safety, side effects and things to watch for

Fluticasone propionate HFA has no boxed warning, but the FDA label lists risks worth knowing. It does not treat an asthma attack or status asthmaticus, so never reach for it as a rescue inhaler. The most common side effects (reported in more than 3% of patients) are upper respiratory infection or inflammation, throat irritation, sinusitis, hoarseness (dysphonia), oral thrush, cough, bronchitis and headache. Rinsing your mouth with water and spitting it out after every use lowers the risk of thrush and hoarseness.

Other label warnings include a higher chance of infections such as chickenpox, measles, tuberculosis and herpes simplex of the eye; hypercorticism and adrenal (HPA-axis) suppression, especially at higher doses or when moving off an oral corticosteroid, where deaths from adrenal insufficiency have occurred during the transfer; paradoxical bronchospasm (stop the inhaler and use your rescue inhaler); slowed growth velocity in children, so height should be monitored; lower bone mineral density; and glaucoma and cataracts, so periodic eye exams are advised. Allergic reactions including rash, hives, angioedema and anaphylaxis have been reported. Fluticasone is processed by CYP3A4, so strong inhibitors such as ritonavir, cobicistat and ketoconazole should be avoided because they raise systemic fluticasone levels and can trigger Cushing's syndrome and adrenal suppression. The canister is under pressure: do not puncture it or expose it to heat or an open flame. This page is general information, not medical advice. Tell your prescriber about every medicine you take, and call them if symptoms get worse or you need your rescue inhaler more often.

Sources & accuracy

This Fluticasone Propionate Hfa information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fluticasone Propionate Hfa on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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