Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Humira Box — prescription drug image

Humira

Humira 1 Auto-injector Kit

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Humira?

Humira 1 Auto-injector Kit contains adalimumab, a medication used to treat various autoimmune conditions. It helps reduce inflammation and manage symptoms in conditions like arthritis and certain skin disorders.

Prescription savings · · · ·

What is Humira ?

Humira 1 Auto-injector Kit contains adalimumab, a medication used to treat various autoimmune conditions. It helps reduce inflammation and manage symptoms in conditions like arthritis and certain skin disorders.

Source: MedlinePlus, U.S. National Library of Medicine

  • Cough, fever, chills, runny or stuffy nose, sore throat, body aches
  • Changes in vision
  • Sores or white patches on your lips, mouth, or throat
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, uneven heartbeat, trouble breathing
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet, joint pain
  • Swollen glands in your neck, underarms, or groin
  • Blistering, peeling, red skin rash, or red, scaly patches on the skin
  • Rapid weight gain, swelling in your hands, ankles, lower legs, or feet
  • Unusual bleeding, bruising, tiredness, weakness, or weight loss
  • Change in how much or how often you urinate, painful urination
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, COPD, heart failure, diabetes, psoriasis, multiple sclerosis, optic neuritis, problems with your immune system, or a history of cancer or Guillain-Barré syndrome. Tell your doctor if you have any type of infection (including hepatitis B or tuberculosis) or an infection that keeps coming back.
  • This medicine may cause the following problems: Increased risk for infectionIncreased risk of certain cancers, including lymphoma or leukemiaNervous system problemsNew or worsening heart failureImmune system problems, including lupus-like syndrome or autoimmune hepatitis
  • You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.
  • The needle cover of the prefilled syringe or pen contains dry natural rubber (a derivative of latex), which may cause allergic reactions in people who are sensitive to latex. Tell your doctor if you have a latex allergy before you start receiving this medicine.
  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Rapid weight gain, swelling in your hands, ankles, lower legs, or feet
  • Sores or white patches on your lips, mouth, or throat
  • Swollen glands in your neck, underarms, or groin
  • Unusual bleeding, bruising, tiredness, weakness, or weight loss
How much does Humira cost without insurance?
Humira is a brand-name biologic with no generic, and the cash price is high and varies by pharmacy and by the strength and quantity your prescriber writes. Rather than quoting a figure that may not match your pharmacy, enter your ZIP code above to see today's cash price near you with a free Rx.com coupon, and compare it with the price of an adalimumab biosimilar if your prescriber says one is appropriate.
Is there a generic version of Humira?
No. Humira is a biologic, so it does not have a generic in the usual sense. Instead, the FDA has approved adalimumab biosimilars, including Amjevita, Cyltezo, Hyrimoz, Hadlima, Yuflyma, Hulio, Idacio, Yusimry, Abrilada, and Simlandi, plus some unbranded adalimumab products. Some carry an interchangeable designation, which in many states can let a pharmacy substitute without a new prescription; others need your prescriber to write for that specific product. Ask your prescriber and pharmacist which options your plan and pharmacy support, and compare prices, since they differ.
How long does it take for Humira to start working?
It depends on the condition being treated and the person. Some people notice improvement within the first several weeks, while others take longer to see the full benefit. Your prescriber will tell you what to expect for your specific condition and when to check back in. Do not stop or change your dose on your own because you have not seen results yet.
What are the most serious side effects of Humira?
The FDA boxed warning covers two things: serious infections and malignancy. Serious infections can lead to hospitalization or death and include tuberculosis, invasive fungal infections, and other bacterial, viral, and opportunistic infections. The malignancy warning covers lymphoma and other cancers reported in children and adolescents on TNF blockers, including rare hepatosplenic T-cell lymphoma, which is usually fatal and has been seen mostly in adolescent and young adult males with Crohn's disease or ulcerative colitis who also take azathioprine or 6-mercaptopurine. Other serious risks on the label include hepatitis B reactivation, demyelinating disease, worsening heart failure, low blood counts, and severe allergic reactions. Call your prescriber right away about fever, persistent cough, weight loss, or any sign of infection.
Can you get Humira for a low copay with the manufacturer savings card?
AbbVie's official savings program for Humira is described on the manufacturer's website. Like most copay cards, it is generally limited to people with commercial insurance, and its terms, eligibility, and any limits vary and can change, so check the current terms directly. People with Medicare, Medicaid, or other government coverage, and people with no insurance, are typically not eligible. If you fall into one of those groups or the card is declined at the pharmacy, a cash-pay Rx.com coupon is the alternative. AbbVie also has a patient assistance program for people who qualify by income and insurance status.
Do you have to get a TB test before starting Humira?
Yes. The label says patients should be tested for latent tuberculosis before starting Humira, and that latent TB should be treated before treatment begins. Testing and monitoring should also continue during treatment. This is because TNF blockers can allow a latent TB infection to reactivate, which is part of the drug's boxed warning.
How much does Humira cost without insurance?
The price of Humira without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 34% off retail prices with a free Rx.com coupon.
What are the common side effects of Humira?
Common side effects of Humira may include: Cough, fever, chills, runny or stuffy nose, sore throat, body aches, Changes in vision, Sores or white patches on your lips, mouth, or throat, Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Humira?
Generic versions may be available for Humira. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Humira on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Humira?
The cheapest pharmacy for Humira depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Humira near you.

Humira Coupons & Prices

Humira 1 Auto-injector Kit

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Humira Box — prescription drug image
Prescription
Humira 1 auto-injector kit (1)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Humira (adalimumab) is a brand-name biologic injection with no substitutable generic, so the price you pay depends heavily on your coverage and your pharmacy. A free Humira coupon from Rx.com is a cash-pay discount you can use at a participating pharmacy when you do not have insurance, when Medicare rules leave you paying cash, or when the manufacturer's savings card is declined. Enter your ZIP code above to see today's price near you, and compare it with your insurance copay and with the adalimumab biosimilars your prescriber may be able to switch you to.

What is Humira and how does it work?

Humira is adalimumab, a human IgG1 monoclonal antibody given as a subcutaneous injection (an injection under the skin). It is a tumor necrosis factor (TNF) blocker and a biologic disease-modifying antirheumatic drug (DMARD). TNF is a protein in the body that drives inflammation. By binding TNF and blocking its activity, adalimumab lowers the inflammation behind several immune-driven conditions.

The FDA has approved Humira for moderate to severe rheumatoid arthritis in adults; polyarticular juvenile idiopathic arthritis in children 2 years and older; psoriatic arthritis in adults; ankylosing spondylitis in adults; Crohn's disease in adults and children 6 years and older; ulcerative colitis in adults and children 5 years and older; moderate to severe chronic plaque psoriasis in adults who are candidates for systemic therapy or phototherapy; hidradenitis suppurativa in patients 12 years and older; and non-infectious intermediate, posterior, and panuveitis in patients 2 years and older. Your prescriber decides the dose and schedule for your condition. This page is information only, not medical advice.

Manufacturer savings card vs. the Rx.com cash coupon

AbbVie runs an official savings program for Humira, described on the manufacturer's own website (humira.com). Like most manufacturer copay cards, it is generally limited to people with commercial (private) insurance, and the terms, eligibility rules, and any limits vary and change over time, so read the program's current terms yourself before counting on it. People with Medicare, Medicaid, other government coverage, or no insurance at all are typically not eligible. AbbVie also operates a patient assistance program for people who qualify based on income and insurance status, which is separate from the copay card and worth asking your prescriber's office about.

The Rx.com coupon is different: it is a cash-pay discount, not insurance and not a copay card. It is the option that still works when you are uninsured, when you are on Medicare, or when the pharmacy tells you the manufacturer card was declined. It is free to use and there is no membership. Enter your ZIP code above to see today's cash price at pharmacies near you, then compare that against your insurance copay and pick whichever is lower. Prices vary a lot by pharmacy, so it is worth comparing.

Is there a generic? Biosimilars and other options

There is no generic Humira. Because adalimumab is a biologic, the lower-cost alternatives are biosimilars, not generics. FDA-approved adalimumab biosimilars marketed in the US include Amjevita (adalimumab-atto), Cyltezo (adalimumab-adbm), Hyrimoz (adalimumab-adaz), Hadlima (adalimumab-bwwd), Yuflyma (adalimumab-aaty), Hulio, Idacio, Yusimry, Abrilada, and Simlandi, along with some unbranded adalimumab products. Some of these are designated interchangeable, which in many states can allow a pharmacy substitution, while others require your prescriber to write for that specific product. Prices differ between these products and between pharmacies, so compare rather than assume any one is cheapest.

If adalimumab is not the right fit, prescribers may consider other TNF blockers such as Enbrel, Remicade, Cimzia, or Simponi; biologics with a different target such as Stelara; oral JAK inhibitors such as Rinvoq or Xeljanz; or a conventional DMARD such as methotrexate. These are not equivalent to one another, and the right choice depends on your diagnosis and history. Talk with your prescriber before changing anything.

Safety information you should know

Humira carries an FDA boxed warning for serious infections and malignancy. Serious infections leading to hospitalization or death have occurred, including tuberculosis (often reactivation of latent TB), invasive fungal infections such as histoplasmosis, coccidioidomycosis, and blastomycosis, and other bacterial, viral, and opportunistic infections. You should be tested for latent TB before starting and monitored during treatment, and latent TB should be treated first. Treatment should be stopped if a serious infection or sepsis develops. Risk is higher when adalimumab is combined with other immunosuppressants such as methotrexate or corticosteroids. The malignancy part of the boxed warning covers lymphoma and other cancers, some fatal, reported in children and adolescents on TNF blockers, and postmarketing cases of hepatosplenic T-cell lymphoma, a rare and usually fatal lymphoma seen mostly in adolescent and young adult males with Crohn's disease or ulcerative colitis taking adalimumab along with azathioprine or 6-mercaptopurine.

Other important risks on the label include hepatitis B reactivation in chronic carriers, new or worsening demyelinating disease (such as multiple sclerosis, optic neuritis, or Guillain-Barre syndrome), new or worsening congestive heart failure, low blood counts including rare aplastic anemia, hypersensitivity reactions including anaphylaxis, lupus-like syndrome, and rare severe liver reactions. Live vaccines should not be given during treatment, so bring immunizations up to date beforehand. Humira should not be combined with anakinra, abatacept, or other biologic DMARDs because of added infection risk. The most common side effects are injection-site reactions, upper respiratory infections, sinusitis, headache, and rash. This is a summary, not the full label and not medical advice. Read the medication guide and talk with your prescriber or pharmacist about your own situation.

Sources & accuracy

This Humira information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Humira on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Browse more medications: starting with H · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!