Diclofenac Potassium
Diclofenac Potassium 50MG
What is Diclofenac Potassium?
Diclofenac is a medication used to relieve mild to moderate pain and to reduce swelling and stiffness caused by conditions like arthritis. Your doctor will determine the right dose for you.Side Effects
- Bloody or black, tarry stools, severe stomach pain, vomiting blood or material that looks like coffee grounds
- Confusion, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
- Change in how much or how often you urinate
Warnings
- Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you have kidney disease, liver disease, asthma, heart failure, high blood pressure, or heart or blood vessel problems, or a history of stomach ulcers or bleeding problems. Tell your doctor if you have phenylketonuria (PKU). Also tell your doctor if you drink alcohol.
- This medicine may cause the following problems:Increased risk of blood clots, heart attack, stroke, or heart failureBleeding problems, including stomach or bowel bleeding or ulcerLiver problemsHigh blood pressureKidney problemsSerious skin reactions, including Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)
- This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
- Tell any doctor or dentist who treats you that you are using this medicine.
Prescription savings · · · ·
What is Diclofenac Potassium ?
Diclofenac is a medication used to relieve mild to moderate pain and to reduce swelling and stiffness caused by conditions like arthritis. Your doctor will determine the right dose for you.- Bloody or black, tarry stools, severe stomach pain, vomiting blood or material that looks like coffee grounds
- Confusion, uneven heartbeat, trouble breathing, numbness or tingling in your hands, feet, or lips
- Change in how much or how often you urinate
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Unusual bleeding, bruising, or weakness
- Rapid weight gain, swelling in your hands, ankles, or feet
- Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, unusual sweating, faintness
- Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg, sudden or severe headache, or problems with vision, speech, or walking
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
- Tell your doctor if you have kidney disease, liver disease, asthma, heart failure, high blood pressure, or heart or blood vessel problems, or a history of stomach ulcers or bleeding problems. Tell your doctor if you have phenylketonuria (PKU). Also tell your doctor if you drink alcohol.
- This medicine may cause the following problems:Increased risk of blood clots, heart attack, stroke, or heart failureBleeding problems, including stomach or bowel bleeding or ulcerLiver problemsHigh blood pressureKidney problemsSerious skin reactions, including Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)
- This medicine may cause a delay in ovulation for women and may affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine.
- Tell any doctor or dentist who treats you that you are using this medicine.
- Your headaches may become worse if you use a headache medicine for 10 or more days per month. Write down how often your headaches occur and how often you use this medicine.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Diclofenac Potassium Coupons & Prices
Diclofenac Potassium 50MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a diclofenac potassium coupon? Diclofenac potassium is the immediate-release form of the prescription NSAID diclofenac, available as a low-cost generic (the brands include Cataflam, Cambia, and Zipsor). Because it is generic, it is usually inexpensive, but the cash price can vary a lot from one pharmacy to the next, so it pays to compare before you fill. Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies and gives you a free discount coupon you can use whether or not you have insurance.
What is diclofenac potassium and how does it work?
Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) in the phenylacetic acid family. Like other NSAIDs, it works by blocking cyclooxygenase (COX) enzymes, which lowers the body's production of prostaglandins, the chemicals that drive pain, swelling, and fever. It is a nonselective COX inhibitor, meaning it acts on both COX-1 and COX-2.
The immediate-release potassium tablets (for example, Cataflam) are FDA-approved to relieve mild to moderate acute pain, to treat primary dysmenorrhea (menstrual cramps), and to manage the signs and symptoms of osteoarthritis and rheumatoid arthritis. The Zipsor liquid-filled capsule form of diclofenac potassium is FDA-approved only for the relief of mild-to-moderate acute pain in patients 12 years and older; it is not approved for osteoarthritis. The Cambia oral-solution form of diclofenac potassium is approved for the acute treatment of migraine attacks, with or without aura, in adults; it is not approved to prevent migraines. The "potassium" salt is the immediate-release version, which gives a faster onset than delayed-release diclofenac sodium.
Diclofenac potassium cost and savings without insurance
Diclofenac potassium is available as an FDA-approved generic, so it is already one of the more affordable prescription NSAIDs. That said, the cash price is not the same everywhere; two pharmacies in the same town can charge very different amounts for the identical tablets. Comparing prices is the single easiest way to avoid overpaying, especially if you do not have insurance or your plan does not cover it well.
Rx.com compares diclofenac potassium prices across more than 60,000 U.S. pharmacies and provides a free discount coupon that works with or without insurance. Enter your ZIP above to see today's price near you, then show the coupon at the pharmacy counter. There is no manufacturer copay savings card for generic diclofenac potassium, so a pharmacy discount coupon is usually the most useful tool for cash-paying patients.
Alternatives and related medicines
Diclofenac comes in more than one salt and formulation, and there are several other NSAIDs your prescriber may consider. Note that some diclofenac capsules, such as Zorvolex, contain diclofenac free acid rather than the potassium or sodium salt and are not interchangeable with them even at the same milligram strength. If you are comparing options, these related pages may help:
- Diclofenac sodium and diclofenac — the delayed-release and general forms of the same active drug.
- Voltaren — a well-known diclofenac brand.
- Meloxicam and celecoxib — other prescription NSAIDs (celecoxib is more COX-2 selective).
- Naproxen and ibuprofen — widely used NSAIDs also sold over the counter at lower strengths.
Which NSAID is right for you depends on your condition, other health issues, and other medicines you take. This is not medical advice; talk with your provider or pharmacist about the best choice.
Safety and boxed warnings
Like all oral prescription NSAIDs, diclofenac potassium carries an FDA boxed warning. First, NSAIDs can raise the risk of serious, potentially fatal cardiovascular events such as heart attack and stroke; this risk may begin early and increases with higher doses and longer use, and these drugs should not be used for pain right before or after coronary artery bypass graft (CABG) surgery. Second, NSAIDs can cause serious, potentially fatal gastrointestinal bleeding, ulcers, and perforation, which can happen at any time and without warning symptoms; older adults and people with prior GI disease are at higher risk.
Other important risks include liver injury (diclofenac can raise liver enzymes more than some other NSAIDs, so monitoring may be needed), kidney injury, higher potassium levels, fluid retention and swelling, worsening of heart failure and high blood pressure, allergic reactions including anaphylaxis, and rare but severe skin reactions. NSAIDs should be avoided at about 20 weeks of pregnancy and later. Use the lowest effective dose for the shortest time needed, and do not combine with other NSAIDs or aspirin unless your provider tells you to. This is general information, not medical advice; review your full history with your provider.
This Diclofenac Potassium information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Diclofenac Potassium on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.