What is Syprine ?

Trientine Hydrochloride is a metal-chelating pharmaceutical agent used primarily for the treatment of Wilson's disease, a genetic disorder that leads to excessive copper accumulation in the body. By binding to copper, Trientine helps to facilitate its excretion through the urine, thereby reducing copper toxicity and preventing associated hepatic and neurological damage. As an alternative to penicillamine, it is particularly useful for patients who cannot tolerate or are inadequately managed by penicillamine therapy.

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Skin rash
• Fever
• Pruritus (itching)

• Not recommended for use in individuals with hypersensitivity to trientine or any of its components.
• Should be used with caution in individuals with renal impairment.
• May cause iron deficiency; iron levels should be monitored regularly.
• Use with caution in pregnancy and breastfeeding; consult with a healthcare provider.
• Regular blood tests may be necessary to monitor liver function and blood cell counts.
• Drug interactions can occur with other chelating agents; consult a healthcare provider before combining treatments.