Four ED meds.
One dose.
Quad Rx combines sildenafil, tadalafil, vardenafil and apomorphine in a liquid that absorbs under your tongue. Prescribed online by an independent U.S.-licensed provider and shipped to your door in plain packaging.
Prescription required. A licensed provider decides whether treatment is right for you. Quad Rx is a compounded medication and is not FDA-approved. Adults 18+.
What matters most to you?
Tap one. Your provider makes the final call based on your health history.
Three blood-flow medicines plus apomorphine for arousal, layered short-acting and long-acting, in a liquid that absorbs under your tongue. Compounded, not FDA-approved.
Prescription required.
Four ingredients. Four jobs.
Most ED pills do one thing: improve blood flow. Quad Rx pairs three blood-flow medicines with one that works on arousal.
Apomorphine
THE AROUSAL INGREDIENTWorks in the brain on dopamine pathways involved in arousal, not on blood flow alone.
Sildenafil
ACTIVE INGREDIENT IN VIAGRA®The most widely prescribed ED medicine. A PDE5 inhibitor that typically lasts about 4 to 6 hours.
Tadalafil
ACTIVE INGREDIENT IN CIALIS®The long-acting one. Tadalafil can stay active for up to 36 hours.
Vardenafil
ACTIVE INGREDIENT IN LEVITRA®A PDE5 inhibitor closely related to sildenafil that typically lasts about 4 to 5 hours.
Short-acting and long-acting, layered together
Typical duration of each ingredient on its ownDurations are for each ingredient taken on its own, from FDA labeling and clinical literature. How Quad Rx works for you depends on your prescribed strength. The four-ingredient combination has not been studied in large clinical trials. Quad Rx is compounded and not FDA-approved.
Pick your pack. Everything else is included.
One monthly price covers the provider visit, the medication and express shipping. Same price on every renewal, and you are only billed if a prescription is approved.
Prescription required. Compounded medications are not FDA-approved. A provider determines eligibility and strength.
Prefer a classic pill? We have those too.
Generic sildenafil and tadalafil are FDA-approved and have decades of real-world use. Same online visit, same one-price model.
Quad Rx
4-in-1 compounded sublingual liquid- How you take it
- Under the tongue
- Works on
- Blood flow and arousal
- Window
- Short and long-acting
- FDA status
- Compounded, not FDA-approved
Sildenafil
Generic for Viagra®, oral tablet- How you take it
- As needed, before sex
- Works on
- Blood flow
- Window
- About 4 to 6 hours
- FDA status
- FDA-approved
Tadalafil
Generic for Cialis®, oral tablet- How you take it
- As needed or low daily dose
- Works on
- Blood flow
- Window
- Up to 36 hours
- FDA status
- FDA-approved
Prescription required for every treatment. An independent licensed provider decides whether a medication is right for you.
From your couch to your door in three steps.
Pick a treatment, answer a few questions
A short online health questionnaire. No waiting room, no appointment to book.
A licensed provider reviews it
An independent U.S.-licensed provider prescribes only if treatment is right for you. If they say no, you are not billed.
Filled and shipped, discreetly
A U.S.-licensed pharmacy fills it and ships free by express delivery in plain packaging.
No waiting room. No pharmacy counter. No awkward conversation.
Real providers. A real pharmacy. Named, not hidden.
Questions men actually ask
How is Quad Rx different from sildenafil or tadalafil alone?
Sildenafil and tadalafil each work on blood flow. Quad Rx combines three blood-flow medicines (sildenafil, tadalafil and vardenafil) with apomorphine, which acts on arousal pathways in the brain, in one dose under the tongue. The single-ingredient pills are FDA-approved; Quad Rx is a compounded medication and is not.
Is Quad Rx FDA-approved?
No. Quad Rx is compounded by a licensed pharmacy for an individual prescription. Sildenafil, tadalafil and vardenafil are each FDA-approved for ED on their own. Apomorphine is not FDA-approved for ED in the United States.
Do I need a prescription?
Yes. You complete a short online questionnaire, and an independent U.S.-licensed provider decides whether treatment is appropriate. If it is, a U.S.-licensed pharmacy fills it and ships it to you.
What if the provider says no?
Then you are not billed. The provider may suggest a different treatment or recommend you see a doctor in person.
Who should not take ED medication?
Men who take nitrates for chest pain (such as nitroglycerin) or riociguat should never take sildenafil, tadalafil or vardenafil. Men with serious heart conditions, uncontrolled blood pressure or a history of priapism need a provider's guidance first. The questionnaire screens for these, so answer it honestly.
Will anyone know what I ordered?
Orders ship in plain packaging with nothing on the outside about what is inside.
Does insurance cover it?
No insurance is needed and none is billed. It is one flat monthly price with the visit and shipping included, and Klarna is available.
Your next step is a short online visit.
Pick a treatment, finish a short online visit, and a licensed provider takes it from there. Not prescribed, not billed.
Prescription required. Quad Rx is compounded and not FDA-approved.
Important safety information
Sildenafil, tadalafil and vardenafil (including as ingredients in Quad Rx) must never be combined with nitrates such as nitroglycerin, recreational nitrates ("poppers") or riociguat. The combination can cause a sudden, life-threatening drop in blood pressure. Use caution with alpha-blockers and other blood pressure medicines. Sexual activity may not be advisable for men with certain heart conditions.
Common side effects include headache, flushing, nasal congestion, indigestion, dizziness and nausea. Seek immediate medical care for an erection lasting more than 4 hours, or for sudden loss of vision or hearing. Tell your provider about every medication you take and any heart, blood pressure, liver or kidney condition.
Compounded medication: Quad Rx is a compounded medication. It is not FDA-approved, and its safety and effectiveness have not been verified by the FDA. Medications are only issued when clinically appropriate after provider evaluation. Rx.com does not manufacture compounded medications.
Rx.com operates as a marketplace platform that connects patients with independently licensed healthcare providers who deliver medical care through the Rx.com Patient Portal. Rx.com does not dispense medication or provide medical services; all clinical decisions are made solely by independent providers, and payment does not guarantee that a prescription will be issued or a medication dispensed. Medications are dispensed by Manifest Pharmacy, 1018 S. Batesville Road, Greer, SC 29650. Provider network: MD Integrations.
Compounded medications are not FDA-approved; their safety and effectiveness have not been verified by the FDA. No compounded medication is equivalent to any brand-name medication. Viagra®, Cialis®, Levitra® and all other brand names and trademarks on this page are the property of their respective owners. Rx.com is not affiliated with, endorsed by, or sponsored by any of them. Photos are of models.
