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Tadalafil Tablet — prescription drug image

Tadalafil

Tadalafil (Cialis)

QUAD by MEDVi · 4-in-1 ED treatment

Tadalafil is one of the 4 meds in QUAD

Sildenafil, tadalafil, PT-141 & L-Citrulline in one sublingual dose · Works in ~15 min · Lasts up to 36 hours

See QUAD by MEDVi From $114/mo · Free online visit
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

What is Tadalafil?

Tadalafil (Cialis) is a prescription medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and certain cases of pulmonary arterial hypertension. Known by the brand name Cialis, Tadalafil can help improve erectile function for up to 36 hours and may also relieve urinary symptoms associated with an enlarged prostate. Learn about Tadalafil uses, dosage, side effects, cost, and how to get a Tadalafil prescription online through Rx.com with convenient mail-order delivery options.

Prescription savings · · · ·

What is Tadalafil ?

Tadalafil (Cialis) is a prescription medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and certain cases of pulmonary arterial hypertension. Known by the brand name Cialis, Tadalafil can help improve erectile function for up to 36 hours and may also relieve urinary symptoms associated with an enlarged prostate. Learn about Tadalafil uses, dosage, side effects, cost, and how to get a Tadalafil prescription online through Rx.com with convenient mail-order delivery options.

  • Sudden loss of vision
  • Painful erection or an erection that lasts longer than 4 hours with or without pain
  • Lightheadedness, fainting
  • Chest pain, trouble breathing
  • Blistering, peeling, or red skin rash
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Sudden decrease in hearing or hearing loss, ringing in the ears, dizziness
  • Sudden decrease in hearing or hearing loss, ringing in the ears, dizziness
  • Sudden loss of vision
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine may cause the following problems: Low blood pressure (especially if taken with other medicines that lower blood pressure)Painful or prolonged erectionHearing or vision problems
  • Tell any doctor who treats you that you are using tadalafil.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lung or breathing problems, diabetes, high cholesterol, cancer (including leukemia, multiple myeloma), sickle cell anemia, bleeding problems, stomach ulcer, problems with your penis, or eye problems. Tell your doctor if you have angina or chest pain during sex, heart disease, heart rhythm problems, high or low blood pressure, or a history of heart attack or stroke. Also tell your doctor if you smoke or drink alcohol.
How long does tadalafil take to work?
Tadalafil is taken by mouth and generally begins working within about 30 minutes to an hour when used as needed. How quickly it works can vary from person to person. Follow your doctor's instructions on when and how to take it.
How long does tadalafil last in your system?
Tadalafil is known for its long duration compared with some other ED medicines, and its effects can last for a day or more. Because it stays in the body longer, your doctor may prescribe it either as needed or as a low daily dose. Ask your provider what schedule is right for you.
What is the difference between tadalafil and Viagra (sildenafil)?
Both tadalafil and sildenafil (the generic form of Viagra) are PDE5 inhibitors used for erectile dysfunction, but they are different medicines. Tadalafil tends to last longer, while sildenafil acts for a shorter time. Your doctor can help you decide which one suits you best.
Can you take tadalafil every day?
Tadalafil can be prescribed as a low daily dose for some people, in addition to being used as needed. Whether daily use is appropriate depends on your condition and overall health, so only take it on the schedule your doctor prescribes.
Is tadalafil the same as Cialis?
Yes. Tadalafil is the active ingredient in Cialis, and generic tadalafil contains the same medicine as the brand. The main difference is cost, since the generic is usually much less expensive than brand-name Cialis.
How much does Tadalafil 5MG cost without insurance?
The price of Tadalafil 5MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Tadalafil 5MG?
Common side effects of Tadalafil 5MG may include: Sudden loss of vision, Painful erection or an erection that lasts longer than 4 hours with or without pain, Lightheadedness, fainting, Chest pain, trouble breathing, Blistering, peeling, or red skin rash. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tadalafil 5MG?
Generic versions may be available for Tadalafil 5MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tadalafil 5MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tadalafil 5MG?
The cheapest pharmacy for Tadalafil 5MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tadalafil 5MG near you.

Tadalafil Coupons & Prices

Tadalafil (Cialis)

QUAD by MEDVi · 4-in-1 ED treatment

Tadalafil is one of the 4 meds in QUAD

Sildenafil, tadalafil, PT-141 & L-Citrulline in one sublingual dose · Works in ~15 min · Lasts up to 36 hours

See QUAD by MEDVi From $114/mo · Free online visit
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.
Tadalafil Tablet — prescription drug image
Prescription
Tadalafil 2.5mg (30)
your area ·
QUAD by MEDVi · 4-in-1 ED treatment

Tadalafil is one of the 4 meds in QUAD

Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours

$114/mo Consult, meds & shipping included 4-in-1 formula
See QUAD by MEDVi Free online visit · No commitment
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

Looking for a tadalafil coupon? Tadalafil is the low-cost generic version of Cialis, and because it is a generic, cash prices are already much lower than the brand. Prices still vary widely from one pharmacy to the next, so comparing before you fill can make a real difference. Rx.com checks tadalafil prices across more than 60,000 pharmacies so you can grab the best available discount in your area. Enter your ZIP above to see today's price near you.

What is tadalafil and how does it work?

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. It is the active ingredient sold under the brand names Cialis, Adcirca, and Alyq. It is FDA-approved to treat erectile dysfunction (ED), the symptoms of benign prostatic hyperplasia (BPH), and ED and BPH together. As Adcirca and Alyq, it is also approved to treat pulmonary arterial hypertension (PAH) to improve the ability to exercise. Tadalafil works by relaxing blood vessels and improving blood flow to specific areas of the body.

A generic version is available, which is why tadalafil typically costs far less than the brand-name Cialis while containing the same active ingredient.

Tadalafil cost and savings without insurance

Because tadalafil is a generic, it is generally already an affordable medication compared with brand-name Cialis. Even so, the cash price can vary a great deal depending on which pharmacy you use, so it pays to compare. There is no manufacturer savings card for generic tadalafil, but a discount coupon can still lower what you pay at the counter.

Rx.com compares tadalafil prices across more than 60,000 pharmacies to help you find the lowest available price nearby. Prices change often and are shown live, so enter your ZIP above to see today's price and print or show your free coupon at the pharmacy.

Tadalafil vs. Cialis and other alternatives

Tadalafil is the same medicine as brand-name Cialis, just sold as a lower-cost generic. Other PDE5 inhibitors used for erectile dysfunction include sildenafil (the generic form of Viagra), vardenafil, and avanafil. They work in similar ways but differ in how quickly they act and how long their effects last.

Which option is right for you depends on your health and how your body responds. Your doctor or pharmacist can help you choose, and you can compare cash prices for each on Rx.com to see which fits your budget.

Important safety information

Tadalafil should never be taken with nitrate medicines such as nitroglycerin or isosorbide, or with riociguat (a guanylate cyclase stimulator), because the combination can cause a severe, life-threatening drop in blood pressure. Do not use tadalafil with recreational nitrates known as "poppers" for the same reason. Use caution if you take alpha-blockers or other blood pressure medicines. Sexual activity may not be advisable for some men with certain heart conditions.

Seek immediate medical care for an erection lasting more than 4 hours (priapism), or for sudden loss of vision or hearing. This is not medical advice; talk with your doctor or pharmacist about your full medical history and other medicines before starting tadalafil.

Sources & accuracy

This Tadalafil information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tadalafil on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Tadalafil — Articles & Guides

13 articles
How Long Does Dutasteride Take to Regrow Hair? Realistic Timeline Month by Month
How Long Does Dutasteride Take to Regrow Hair? Realistic Timeline Month by Month
Get a realistic month-by-month timeline for dutasteride hair regrowth, backed by clinical trial numbers and real-world tips. Learn what slows results, how to curb early shedding, and the red-flag side effects that mean it’s time to call your doctor.
Will Cialis (Tadalafil) Appear on a Drug Test?
Will Cialis (Tadalafil) Appear on a Drug Test?
Does tadalafil show up on a drug test? This in-depth guide explains how workplace and athletics panels work, why PDE-5 inhibitors like Cialis aren’t included, when they can be detected in specialized labs, and how to protect your prescription privacy.
Why Sex Feels Hard: Performance Anxiety and Erectile Dysfunction
Why Sex Feels Hard: Performance Anxiety and Erectile Dysfunction
Struggling to stay hard when it matters? You’re not alone. This in-depth guide explains the link between anxiety and erectile dysfunction, shows how many men it affects, and walks you through proven fixes—from quick breathing tricks to prescription pills shipped discreetly by Rx.com.
How to Get Tadalafil Online for Erectile Dysfunction
How to Get Tadalafil Online for Erectile Dysfunction
Tadalafil is the longest-acting oral ED medicine. Learn exactly how it works, how much it costs, and how to order it online through Rx.com’s discreet telehealth service.
Does Baking Soda Help Erectile Dysfunction? Evidence, Risks & Better Options
Does Baking Soda Help Erectile Dysfunction? Evidence, Risks & Better Options
TikTok says a spoonful of baking soda can give you a stronger erection. The science says otherwise. Learn why sodium bicarbonate doesn’t treat erectile dysfunction, the real risks of DIY ‘cures,’ and evidence-backed options that do work.
Tadalafil for Erectile Dysfunction: How the “Weekend Pill” Works and Where to Get It Online
Tadalafil for Erectile Dysfunction: How the “Weekend Pill” Works and Where to Get It Online
Comprehensive guide to tadalafil (Cialis) for erectile dysfunction. Explains how it works, who benefits, dosing schedules, side-effects, real-world results and how to order it online through Rx.com’s discreet telehealth service.
How to Last Longer in Bed: Doctor-Approved Tips That Really Work
How to Last Longer in Bed: Doctor-Approved Tips That Really Work
Struggling to last as long as you’d like during sex? This in-depth guide explains why ejaculation happens quickly, who’s most at risk, and the doctor-approved techniques and medications that can help you extend pleasure for both partners.
Quad for Men Review: Does This 4-in-1 ED Supplement Work?
Quad for Men Review: Does This 4-in-1 ED Supplement Work?
Quad for Men promises prescription-like erection support without a doctor visit. Our clinicians dissect the formula, show what the science says, compare costs with sildenafil, and explain when you still need to see a healthcare provider.
Tadalafil (Cialis)- How Long It Lasts, Best Dose & Easy Online Ordering
Tadalafil (Cialis)- How Long It Lasts, Best Dose & Easy Online Ordering
Everything men 40–70 need to know about tadalafil—how fast it works, how long it lasts, daily vs on-demand dosing, side-effects, success rates and real-world savings. Plus, how to get a prescription online and have tablets shipped discreetly to your door.
Erectile Dysfunction: The Truth About Causes, Cures & Ordering Treatment Online
Erectile Dysfunction: The Truth About Causes, Cures & Ordering Treatment Online
A doctor-reviewed guide to what really causes erectile dysfunction, science-backed fixes from lifestyle changes to prescription pills, and the fastest way to get treatment delivered to your door.
How to Support a Partner With Erectile Dysfunction (Without Killing the Mood)
How to Support a Partner With Erectile Dysfunction (Without Killing the Mood)
Erectile dysfunction doesn’t just affect the person with the erection—it affects the couple. This guide explains why ED happens, what women say really helps, and how to get affordable treatment delivered to your door.
Which Cialis (tadalafil) dose is best for erectile dysfunction?
Which Cialis (tadalafil) dose is best for erectile dysfunction?
Choosing the right Cialis (tadalafil) dose can make or break your erectile-dysfunction treatment. This evidence-based guide compares the 5 mg, 10 mg, and 20 mg tablets, daily vs. on-demand schedules, side-effect risks, and money-saving tips — plus how to get prescription ED care online through Rx.com.
Over-the-Counter Viagra Alternatives: What Works and What’s a Waste?
Over-the-Counter Viagra Alternatives: What Works and What’s a Waste?
Not every “Viagra-like” pill at the gas station does what it promises. Learn which over-the-counter options have any science behind them, the risks of hidden prescription ingredients, and the safest way to get effective erectile-dysfunction treatment today.
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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