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Healthy aging treatments online: sermorelin and NAD+

Aging well,
prescribed online.

Growth hormone output and NAD+ levels both fall with age. Rx.com offers two compounded injections you use at home: sermorelin, which signals your pituitary to release more of your own growth hormone, and NAD+, a coenzyme every cell uses to make energy. Prescribed online by an independent U.S.-licensed provider and shipped to your door.

Online visit included At-home injections No insurance needed

Prescription required. A licensed provider decides whether treatment is right for you. Sermorelin and NAD+ are compounded medications and are not FDA-approved. Adults 18+.

Middle-aged man jogging on a tree-lined path
Two ways to start

Sermorelin or NAD+: compare our healthy aging treatments

Each has its own short online visit. Your provider makes the final call based on your health history.

NIGHTLY INJECTION
Compounded sermorelin vial

Sermorelin

Compounded injection, 3 mg/mL, 5 mL vial

A lab-made copy of the active part of growth hormone-releasing hormone (GHRH). Instead of supplying growth hormone, it signals your pituitary to release more of your own, on your body's natural nightly rhythm.

How you take it
One small injection at bedtime
Works on
Your own growth hormone release
FDA status
Compounded, not FDA-approved
From $149/mo on the 3-month plan See if you qualify Sermorelin details
AT-HOME INJECTION
Compounded NAD+ injection vial

NAD+ injections

Compounded injection, 100 mg/mL (10 mL vial)

NAD+ is a coenzyme every cell uses to make energy and repair DNA, and your levels fall with age. At-home injections cost a fraction of IV drips.

How you take it
Under the skin, on your provider's schedule
Works on
Cellular energy
FDA status
Compounded, not FDA-approved
From $99/mo on the 3-month plan See if you qualify NAD+ details

Prescription required for every treatment. Plans are paid upfront: 3 months or a single month. An independent licensed provider decides whether a medication is right for you.

How it works

From your couch to your door in three steps.

Woman on her sofa answering a health questionnaire on her phone Step 1

Answer a few questions

A short online health questionnaire. No waiting room, no appointment to book.

Provider reviewing patient information at a computer Step 2

A licensed provider reviews it

An independent U.S.-licensed provider prescribes only if treatment is right for you.

Woman opening a small delivery box on her sofa Step 3

Compounded and shipped to you

A licensed U.S. pharmacy compounds your prescription and ships it to your door, with instructions for at-home use.

Learn more

Sermorelin and NAD+ articles & guides

Questions to Ask Before Starting Sermorelin Thinking about peptide therapy? This guide walks you through the critical safety, monitoring and practical que... Prescription NAD+ Nasal Spray vs. DIY and Research Sprays: Why the Source Matters Thinking about mixing your own NAD+ nasal spray or buying a “research” bottle online? Learn why a prescription... NAD+ Nasal Spray vs. NAD+ Injections: Which Should You Choose? Trying to decide between NAD+ nasal spray and injections? This side-by-side guide explains how each format is... How to Talk to Your Doctor About Sermorelin Unsure how to raise sermorelin with your healthcare provider? This step-by-step guide shows you how to prepare... How Long Do NAD+ Injections Take to Work? A Realistic Timeline NAD+ injections don’t deliver an overnight energy jolt. Most people notice better sleep and clearer thinking a... NAD+ Nasal Spray for Brain Fog and Focus: What Studies Have Examined People on Reddit and TikTok claim NAD+ nasal spray erases brain fog in minutes, but human research is still th... Do You Need Lab Work Before Starting Sermorelin? Thinking about starting sermorelin? This guide explains which blood tests most prescribers require first, why... Does NAD+ Nasal Spray Actually Absorb? What the Evidence Says Wondering if NAD+ nasal sprays really get nicotinamide adenine dinucleotide into your body? This evidence-base... Is NAD+ Nasal Spray Worth It? An Honest Buyer's Guide Thinking about trying NAD+ nasal spray? This detailed guide explains how it works, who it helps, who should av... Switching to Sermorelin From Another Provider: What to Know Transferring your sermorelin care to a new clinic is easier than most people expect. This step-by-step guide c... Sermorelin and Other Medications: Interactions to Tell Your Provider About Sermorelin can boost growth-hormone release, but several everyday drugs, from steroids to thyroid pills, can c... Ordering NAD+ Nasal Spray Online: Shipping, Storage and How to Use It Compounded NAD+ nasal spray from Rx.com ships safely without refrigeration. This guide explains why, how to st...
Browse all guides →

Healthy aging questions

What is the difference between sermorelin and NAD+?

They work in different ways. Sermorelin is a lab-made copy of the active part of growth hormone-releasing hormone (GHRH): it signals your pituitary gland to release more of your own growth hormone, and it is taken as one small injection at bedtime. NAD+ is a coenzyme every cell uses to make energy and repair DNA, and your levels fall with age; it is injected at home, usually under the skin, on a schedule your provider sets.

Are sermorelin and NAD+ FDA-approved?

No. Both are compounded medications prepared by a licensed U.S. pharmacy for an individual prescription. Compounded medications are not FDA-approved, and the FDA has not reviewed them for safety, effectiveness or quality.

Do I need a prescription?

Yes. You answer a short online health questionnaire, and an independent U.S.-licensed provider decides whether treatment is appropriate. If it is, a licensed U.S. pharmacy fills your prescription and ships it to you.

Can I use both?

Each is its own prescription and its own online visit. Start with the one you are most interested in and tell the provider about every other treatment, medication and supplement you use. The provider decides what is appropriate for you.

Who should not use them?

Neither is for use during pregnancy or breastfeeding. Sermorelin is not appropriate for people with active cancer or a recent cancer history, and for NAD+ the provider needs to know about any history of cancer. Share your complete health history and medication list during the intake.

Does insurance cover it?

No insurance is needed and none is billed. Both are cash pay with upfront pricing: a 3-month plan paid upfront or a single month.

Your next step is a short online visit.

Pick a treatment, answer a few questions, and a licensed provider takes it from there.

Prescription required. Sermorelin and NAD+ are compounded and not FDA-approved.

Important safety information

Sermorelin

The most common side effects are injection-site redness, swelling or soreness, facial flushing, headache and nausea. Some people notice dizziness, restlessness or trouble sleeping. These are usually mild and tend to fade within the first week or two.

Sermorelin is not appropriate for people with active cancer or a recent cancer history, or during pregnancy or breastfeeding. Untreated hypothyroidism and diabetes need extra review, and some medications, including glucocorticoids (such as prednisone), can interfere with it. Share your complete health history and medication list during the intake. Get emergency care for trouble breathing or swelling of the face, tongue or throat.

NAD+ injections

Common side effects include injection-site soreness or redness, flushing, headache and lightheadedness; nausea, fatigue, sleep changes or jitteriness are less common. Do not use NAD+ if you are pregnant or breastfeeding. Tell the provider about all your health conditions, including any history of cancer, and every medication and supplement you take. Get medical care right away for signs of an allergic reaction such as hives, swelling of the face or throat, or trouble breathing.

Compounded medications: Sermorelin and NAD+ injections are available only with a prescription from a licensed provider after a health evaluation. Compounded medications are prepared by a licensed compounding pharmacy and are not FDA-approved products; the FDA has not evaluated them for safety, effectiveness or quality. They are not intended to diagnose, treat, cure or prevent any disease, and statements on this page have not been evaluated by the FDA. Individual results vary.

Medical services: All medical services, including clinical evaluations, treatment planning and prescribing decisions, are provided exclusively by licensed independent medical providers. Rx.com provides the technology platform and administrative coordination services, does not employ healthcare providers, and does not practice medicine. Rx.com does not manufacture compounded medications. This page is for informational purposes and is not a substitute for professional medical advice. Photos are of models.

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