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Primatene Mist Inhaler — prescription drug image

Primatene Mist

Primatene Mist 11.7GM of 0.125MG/ACT

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What is Primatene Mist?

Primatene Mist is an over-the-counter inhaler that provides temporary relief of mild, intermittent asthma symptoms, including wheezing, chest tightness, and shortness of breath. It contains epinephrine, a bronchodilator that works quickly to open the airways and make breathing easier.

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What is Primatene Mist ?

Primatene Mist is an over-the-counter inhaler that provides temporary relief of mild, intermittent asthma symptoms, including wheezing, chest tightness, and shortness of breath. It contains epinephrine, a bronchodilator that works quickly to open the airways and make breathing easier.

  • Nervousness
  • Headache
  • Tremor
  • Nausea
  • Increased heart rate
  • Dizziness
  • Sore throat
  • Do not use if you have a heart disease without consulting your doctor
  • Do not use more frequently than recommended
  • Not for long-term use; intended for temporary relief
  • May interact with other medications
  • Consult a healthcare provider if symptoms worsen or do not improve
  • Potential risks if used during pregnancy or breastfeeding - consult your doctor
  • May increase blood pressure
Is Primatene Mist available over the counter without a prescription?
Yes. Primatene Mist HFA is sold over the counter, so you can buy it without a prescription. It is the only FDA-approved over-the-counter asthma inhaler in the United States, intended for people 12 and older who have already been diagnosed with asthma.
Is Primatene Mist safe to use for asthma?
It can be used for temporary relief of mild, intermittent asthma symptoms in people who have already been diagnosed with asthma, when used exactly as the label directs. It is not for severe or persistent asthma and is not a replacement for a doctor-prescribed controller medicine. Because epinephrine can raise heart rate and blood pressure and cause tremor or nervousness, ask a doctor before use if you have heart disease, high blood pressure, diabetes, thyroid disease, or certain other conditions.
How many puffs of Primatene Mist can I use in a day?
The label says to take one inhalation, wait about a minute, and if needed take one more. Do not use more than 2 inhalations at a time and do not use more than 8 inhalations in 24 hours. Needing more than 8 inhalations in a day, or having more than 2 asthma attacks in a week, is a warning sign — seek emergency care and see your doctor.
What is the difference between Primatene Mist and an albuterol inhaler?
Primatene Mist contains epinephrine and is available over the counter, while albuterol inhalers require a prescription. Albuterol is more selective for the airways and usually causes fewer whole-body effects such as a fast heartbeat or jitteriness, which is why doctors most often prescribe it as a rescue inhaler. Both open the airways to relieve symptoms, but albuterol is generally the preferred prescription option.
Does Primatene Mist require a prescription?
No. Primatene Mist is an over-the-counter product, so no prescription is required to buy it. Prices can still vary between pharmacies, and an Rx.com coupon lets you compare the cash price near you — enter your ZIP to see today's price.
How much does Primatene Mist 11.7GM of 0.125MG/ACT cost without insurance?
The price of Primatene Mist 11.7GM of 0.125MG/ACT without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Primatene Mist 11.7GM of 0.125MG/ACT?
Common side effects of Primatene Mist 11.7GM of 0.125MG/ACT may include: Nervousness, Headache, Tremor, Nausea, Increased heart rate. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Primatene Mist 11.7GM of 0.125MG/ACT?
Generic versions may be available for Primatene Mist 11.7GM of 0.125MG/ACT. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Primatene Mist 11.7GM of 0.125MG/ACT on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Primatene Mist 11.7GM of 0.125MG/ACT?
The cheapest pharmacy for Primatene Mist 11.7GM of 0.125MG/ACT depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Primatene Mist 11.7GM of 0.125MG/ACT near you.

Primatene Mist Coupons & Prices

Primatene Mist 11.7GM of 0.125MG/ACT

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Primatene Mist Inhaler — prescription drug image
Prescription
Primatene Mist 11.7gm of 0.125mcg/act (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a Primatene Mist coupon? Primatene Mist (Primatene MIST HFA) is an inhaled epinephrine aerosol and the only FDA-approved over-the-counter asthma inhaler sold in the United States. It offers temporary relief of mild symptoms of intermittent asthma — wheezing, chest tightness, and shortness of breath — in adults and children 12 and older who have already been diagnosed with asthma by a doctor. Because it is sold over the counter, you do not need a prescription to buy it, and an Rx.com coupon can help you compare what you would pay at pharmacies near you. Enter your ZIP above to see today's price.

What Primatene Mist is and how it works

Primatene Mist HFA contains epinephrine, a fast-acting bronchodilator that belongs to a group of medicines called sympathomimetics (alpha- and beta-adrenergic agonists). When inhaled, it relaxes the muscles around the airways so they open up, which can quickly ease mild wheezing, chest tightness, and shortness of breath. It is meant only for the temporary relief of mild, intermittent asthma symptoms in people 12 and older who have already been diagnosed with asthma by a doctor.

Primatene Mist is not a controller or maintenance medicine. It does not treat the underlying inflammation of asthma and is not intended for severe or persistent asthma. Medical guidelines discourage using it in place of a doctor-prescribed asthma controller. Talk with your provider about a long-term asthma plan; this product is not a substitute for that care.

How to use it, and how to save with an Rx.com coupon

Follow the Drug Facts label and your doctor's guidance. Shake the inhaler well, prime it before first use as directed, and take one inhalation at the first sign of symptoms. If you are not relieved in about one minute, the label allows one more inhalation. Do not use more than 2 inhalations at once and do not use more than 8 inhalations in 24 hours. Rinse the mouthpiece and let it dry as directed to keep it working properly.

Because Primatene Mist is sold over the counter, prices can vary a lot from one pharmacy to the next. Some over-the-counter products cost less when you use a pharmacy discount coupon or when a prescriber writes them as a prescription. An Rx.com coupon is free to use and lets you compare the cash price at pharmacies near you — enter your ZIP above to see today's price. There is no manufacturer copay card for this product; you can find official product information on the manufacturer's own website at Primatene.com, and any promotional terms there may vary.

Primatene Mist vs. prescription inhalers

Primatene Mist uses epinephrine and is the only asthma inhaler you can buy without a prescription. Most doctors, however, prescribe short-acting inhalers that use albuterol, a different bronchodilator that is more selective for the airways and generally causes fewer whole-body effects such as a racing heart or jitteriness. If you find yourself reaching for Primatene Mist often, that is a sign your asthma may not be well controlled and you should see a provider.

Prescription rescue-inhaler options your doctor may discuss include albuterol and brand versions such as Ventolin HFA and ProAir HFA. Injectable epinephrine is a different product used for severe allergic reactions, not for routine asthma symptom relief. These prescription products require a prescription, but an Rx.com coupon can help you compare their prices too.

Safety and when to get help

Primatene Mist is only for people who have been diagnosed with asthma by a doctor — do not use it if you have never been diagnosed with asthma. Because epinephrine can affect the heart and nervous system, it may cause a rapid or irregular heartbeat, higher blood pressure, tremor, nervousness, or trouble sleeping. Stop use and contact a doctor if these happen. Avoid caffeine while using it, and ask a doctor before use if you have heart disease, high blood pressure, diabetes, thyroid disease, glaucoma, a seizure disorder, or trouble urinating due to an enlarged prostate, or if you take MAO inhibitors, tricyclic antidepressants, or other stimulant or decongestant medicines.

Get emergency care if your symptoms are not relieved within 20 minutes, if they get worse, if you need more than 8 inhalations in 24 hours, or if you have more than 2 asthma attacks in a week — these can be signs of a serious problem. This information is not medical advice; talk with your own provider about whether Primatene Mist is right for you and about a proper asthma treatment plan.

Sources & accuracy

This Primatene Mist information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Primatene Mist on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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