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Metformin Tablet — prescription drug image

Metformin

Metformin

Prescriptions & Refills
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What is Metformin?

Metformin is one of the most commonly prescribed medications for type 2 diabetes and is often recommended as a first-line treatment to help lower blood sugar levels. It works by reducing glucose production in the liver and improving the body's sensitivity to insulin, making it an effective and affordable option for long-term diabetes management.

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  • Confusion, fast heartbeat, increased hunger, shakiness
  • Trouble breathing, slow heartbeat, lightheadedness, dizziness
  • Stomach pain, nausea, vomiting, muscle pain or cramping
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever or chills
  • Unusual tiredness or weakness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, heart failure, blood circulation problems, anemia, metabolic acidosis, an adrenal gland or pituitary gland disorder, vitamin B12 deficiency, or had a heart attack. Tell your doctor if you drink alcohol.
  • Too much of this medicine can cause a rare, but serious condition called lactic acidosis.
  • Part of the extended-release tablet may pass in your stool. This is normal.
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine before you have surgery, an x-ray, CT scan, or other medical test.
  • This medicine may cause some premenopausal women who do not have regular monthly periods to ovulate. This can increase the chance of pregnancy. If you are a woman of childbearing potential, discuss birth control options with your doctor.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
How much does Metformin cost without insurance?
The price of Metformin $25 without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Metformin 500MG?
Common side effects of Metformin 500MG may include: Confusion, fast heartbeat, increased hunger, shakiness, Trouble breathing, slow heartbeat, lightheadedness, dizziness, Stomach pain, nausea, vomiting, muscle pain or cramping, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Fever or chills. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Metformin 500MG?
Generic versions may be available for Metformin 500MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Metformin 500MG on Rx.com to compare generic and brand prices at pharmacies near you.
Is Metformin available over the counter?
No, metformin is not available over the counter in the United States. It is a prescription-only medication because a healthcare provider should evaluate whether it is appropriate based on your medical history, kidney function, and other medications you may be taking. If you're interested in starting metformin, a licensed provider can determine whether it's a safe and effective treatment option for your individual health needs.

Metformin Coupons & Prices

Metformin

What is Metformin ?

Metformin is one of the most commonly prescribed medications for type 2 diabetes and is often recommended as a first-line treatment to help lower blood sugar levels. It works by reducing glucose production in the liver and improving the body's sensitivity to insulin, making it an effective and affordable option for long-term diabetes management.

Prescriptions & Refills
Compare 60,000+ US pharmacies · save up to 90%
Metformin Tablet — prescription drug image
Prescription
Metformin 500mg (30)
43215 ·
43215 Change ZIP

Metformin is a prescription medication used primarily to treat type 2 diabetes by helping the body better regulate blood sugar levels. For decades, it has remained the first-line medication recommended by many healthcare providers because of its proven effectiveness, long safety record, and low cost. In addition to improving blood sugar control, metformin may help some patients experience modest weight loss or maintain their current weight, unlike certain diabetes medications that can contribute to weight gain.

Metformin works in several ways to improve glucose control. It reduces the amount of sugar produced by the liver, decreases the amount of glucose absorbed from food, and increases the body's sensitivity to insulin, allowing cells to use glucose more efficiently. These combined effects help lower both fasting and after-meal blood sugar levels while reducing A1C over time.

The medication is available in both immediate-release and extended-release formulations and is typically taken once or twice daily with food to reduce stomach-related side effects. Most patients begin with a low dose that is gradually increased based on their blood sugar response and tolerance.

Common side effects include nausea, diarrhea, stomach discomfort, gas, and changes in bowel habits, particularly during the first few weeks of treatment. These symptoms often improve as the body adjusts, especially when the medication is taken with meals or when using an extended-release version. Although rare, metformin carries a warning for lactic acidosis, a serious medical condition that is more likely to occur in people with significant kidney disease or certain other medical conditions. Your healthcare provider will typically monitor kidney function before and during treatment.

Beyond diabetes management, metformin is sometimes prescribed off-label for conditions such as prediabetes, insulin resistance, and Polycystic Ovary Syndrome (PCOS), where improving insulin sensitivity may provide additional health benefits. Whether used alone or alongside other diabetes medications, metformin continues to be one of the most trusted and widely used treatments for helping patients achieve better long-term blood sugar control.

Metformin — Articles & Guides

12 articles
Compounded Tirzepatide Appetite Suppression: How to Eat Enough Protein
Compounded Tirzepatide Appetite Suppression: How to Eat Enough Protein
Compounded tirzepatide can erase hunger so completely that patients forget to eat. This guide explains the science of that appetite switch-off and—more importantly—exactly how to hit your daily protein and calorie targets so you lose fat, not muscle, while keeping side effects low.
How to Break a Weight-Loss Plateau on Compounded Semaglutide
How to Break a Weight-Loss Plateau on Compounded Semaglutide
A year into compounded semaglutide and the scale won’t budge? This expert guide explains why plateaus happen, how dose titration, macro tweaks, and strength training reignite fat loss, and the red-flag symptoms that mean it’s time to call your provider.
Constipation on Tirzepatide: How to Get Moving Again
Constipation on Tirzepatide: How to Get Moving Again
Constipation is one of the least-talked-about side effects of tirzepatide. This guide explains why it happens and lays out pharmacist-backed ways to get comfortable again—from magnesium citrate emergencies to daily fiber habits and when to call the doctor.
Why Tirzepatide Can Feel Like the Flu—and What to Do About It
Why Tirzepatide Can Feel Like the Flu—and What to Do About It
Worried the weekly tirzepatide shot is giving you a never-ending cold? This guide separates typical GLP-1 side effects from true illness and shows proven ways to feel better without derailing weight-loss results.
Tirzepatide Near Me Isn’t Your Only Option: How to Start Treatment Online Today
Tirzepatide Near Me Isn’t Your Only Option: How to Start Treatment Online Today
Wondering where to find tirzepatide without driving all over town? This step-by-step guide shows U.S. adults how to complete a quick telehealth exam, compare prices, and start FDA-approved GLP-1 treatment—all through Rx.com.
How to Find the Cheapest Tirzepatide Online in 2026
How to Find the Cheapest Tirzepatide Online in 2026
Learn exactly how to track down the cheapest tirzepatide online. From pharmacy price comparisons and free Rx coupons to telehealth membership plans and compounded alternatives, this guide shows seven proven ways to keep more money in your wallet while staying safe.
Buy Semaglutide Online: The Weight-Loss Injection Explained
Buy Semaglutide Online: The Weight-Loss Injection Explained
Looking for an affordable weight-loss shot? This guide shows exactly how to buy semaglutide online for as little as $149 a month through Rx.com, compare prices at U.S. pharmacies, and decide if it’s right for you.
How long does tirzepatide take to work?
How long does tirzepatide take to work?
Tirzepatide is the first dual GIP/GLP-1 medicine approved for type 2 diabetes and obesity, but how quickly will you notice lower blood sugar or weight loss? Get the full timeline, dosing chart, and science-backed tips to help the medication work at its best.
Compounded Tirzepatide: How It Works, Legality, Cost, and Safer Alternatives
Compounded Tirzepatide: How It Works, Legality, Cost, and Safer Alternatives
Thinking about compounded tirzepatide for weight loss or diabetes? This guide explains how the compounded version works, whether it’s legal in 2026, typical monthly cost, safety red flags, and smart alternatives if supply rules change.
Is glp1 the same as Ozempic
Is glp1 the same as Ozempic
GLP-1 is a naturally occurring gut hormone, while Ozempic is a brand-name semaglutide injection that mimics GLP-1. Learn how they differ, when each is used, and ways to pay 53–87% less at the pharmacy with Rx.com.
How to Get a Trulicity Prescription Online for Type 2 Diabetes
How to Get a Trulicity Prescription Online for Type 2 Diabetes
Trulicity (dulaglutide) is a once-weekly GLP-1 receptor agonist injection for Type 2 diabetes. Licensed providers can prescribe or refill it through a telehealth visit, with the prescription sent straight to your pharmacy.
How to Get a Toujeo SoloStar Prescription Online
How to Get a Toujeo SoloStar Prescription Online
Toujeo SoloStar is a concentrated long-acting insulin used to manage Type 2 and Type 1 diabetes. Licensed providers can evaluate and prescribe it through telehealth, with the prescription sent directly to your pharmacy.

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