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Ergotamine Tartrate Jar — prescription drug image

Ergotamine Tartrate

Ergotamine Tartrate 1GM of

What is Ergotamine Tartrate?

Ergotamine Tartrate is a medication primarily used to prevent and treat migraine headaches, often in combination with other ingredients like caffeine. It works by constricting blood vessels around the brain and affecting serotonin receptors, which helps alleviate the pain and other symptoms associated with migraines. Due to its potential side effects and interactions with other medications, Ergotamine Tartrate should be used under strict medical supervision.

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What is Ergotamine Tartrate ?

Ergotamine Tartrate is a medication primarily used to prevent and treat migraine headaches, often in combination with other ingredients like caffeine. It works by constricting blood vessels around the brain and affecting serotonin receptors, which helps alleviate the pain and other symptoms associated with migraines. Due to its potential side effects and interactions with other medications, Ergotamine Tartrate should be used under strict medical supervision.
  • Nausea
  • Vomiting
  • Numbness or tingling of fingers and toes
  • Muscle pain in the arms and legs
  • Weakness in the legs
  • Chest pain
  • Irregular heartbeat
  • Do not use with certain medications for HIV, hepatitis C, and fungal infections because of potentially severe drug interactions
  • Do not use in pregnancy as it can cause harm to the fetus
  • Avoid in patients with peripheral vascular disease, coronary heart disease, hypertension, or kidney disease
  • Overuse of ergotamine can increase the risk of medication-overuse headaches
  • Increased risk of fibrosis including retroperitoneal, pleural, and cardiac valvular fibrosis after prolonged use
What is ergotamine tartrate used for?
Ergotamine tartrate is FDA-approved to abort or prevent vascular headaches, including migraine, migraine variant, and cluster headache (sometimes called by the older name "histaminic cephalalgia"). It's taken at the start of an attack rather than on a daily schedule.
Is ergotamine tartrate the same as Cafergot?
Not exactly. Ergotamine tartrate is the active ingredient, and it has been combined with caffeine in various branded and generic products over the years. Check the specific product label with your pharmacist, since formulations and availability differ.
What drugs interact dangerously with ergotamine tartrate?
Potent CYP3A4 inhibitors — including certain macrolide antibiotics, azole antifungals, and protease inhibitors — can cause serious or life-threatening peripheral ischemia and vasospasm when combined with ergotamine tartrate, and these combinations are contraindicated. Other vasoconstrictors and triptans should also not be combined with it. Always give your pharmacist a full list of your medications.
Why was ergotamine tartrate replaced by triptans for migraine?
Triptans such as sumatriptan and rizatriptan became the more commonly used acute migraine treatments after their introduction, though ergotamine tartrate remains an FDA-approved option for some patients. The choice between them depends on individual health factors, so ask your provider what's appropriate for you.
Can you take ergotamine tartrate every day for headaches?
No. Ergotamine tartrate is meant for use at the onset of a headache attack, not for chronic daily administration. Long-term or frequent use has been linked to rare fibrotic complications. Follow your provider's dosing instructions and don't exceed them.
How much does Ergotamine Tartrate cost without insurance?
The price of Ergotamine Tartrate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Ergotamine Tartrate?
Common side effects of Ergotamine Tartrate may include: Nausea, Vomiting, Numbness or tingling of fingers and toes, Muscle pain in the arms and legs, Weakness in the legs. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Ergotamine Tartrate?
Generic versions may be available for Ergotamine Tartrate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Ergotamine Tartrate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Ergotamine Tartrate?
The cheapest pharmacy for Ergotamine Tartrate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Ergotamine Tartrate near you.

Ergotamine Tartrate Coupons & Prices

Ergotamine Tartrate 1GM of

Ergotamine Tartrate Jar — prescription drug image
Prescription
Ergotamine Tartrate 1gm of (90)
your area ·

Ergotamine Tartrate prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
1gm of · Jar 90 $13,434.65

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for an ergotamine tartrate coupon? Ergotamine tartrate is a generic migraine medication, but the price you're quoted can still vary widely from one pharmacy to the next — enter your ZIP above and Rx.com compares pricing across 60,000+ pharmacies so you can see today's price before you fill.

What is ergotamine tartrate and how does it work?

Ergotamine tartrate is an ergot alkaloid that acts as a vasoconstrictor and serotonin-receptor agonist. It's FDA-approved for the abortion or prevention of vascular headaches, including migraine, migraine variant, and cluster headache (also known by the older name "histaminic cephalalgia"). It's meant to be taken at the onset of an attack, not used as a chronic daily medication.

The sublingual (under-the-tongue) tablet is sold under the brand name Ergomar. Ergotamine tartrate is also combined with caffeine in generic tablet and suppository products, including Migergot; terms and formulation details vary, so check the specific product label with your pharmacist.

Ergotamine tartrate cost and coupon savings

Ergotamine tartrate is available as a generic, but that doesn't mean the price is the same everywhere — cash prices for generic drugs can differ significantly by pharmacy, location, and even day to day. Rather than assuming any one pharmacy has the best price, it pays to compare.

Enter your ZIP code above to see current pricing at pharmacies near you, and check whether a coupon lowers your out-of-pocket cost at a specific location. If your plan covers ergotamine tartrate, it's also worth comparing your insurance copay against the cash price, since the lower option isn't always the same for every patient.

Alternatives to ergotamine tartrate for migraine

Ergotamine tartrate was one of the original acute migraine treatments, but it has largely been supplanted in first-line use by newer options. Other drugs used for acute or preventive migraine treatment include sumatriptan and rizatriptan (triptans used at the onset of an attack), dihydroergotamine (a related ergot derivative), and propranolol (used for migraine prevention rather than acute treatment). Caffeine-containing combination products are also used alongside ergotamine tartrate; you can read more about caffeine separately.

Whether any of these is a reasonable option for you depends on your health history and other medications — talk to your provider before switching.

Ergotamine tartrate safety information

Ergotamine tartrate carries a serious risk of peripheral ischemia and vasospasm when taken with potent CYP3A4 inhibitors, such as certain macrolide antibiotics, azole antifungals, and protease inhibitors — these combinations are contraindicated. It should not be used by people with peripheral, coronary, or cerebrovascular vascular disease, uncontrolled high blood pressure, or sepsis, and it is contraindicated in pregnancy. It should not be combined with other vasoconstrictors or triptans.

Long-term or chronic use has been linked to rare fibrotic complications affecting the retroperitoneum, lungs, or heart valves (ergotism), which is why ergotamine tartrate is intended for occasional use at the onset of a headache, not daily use. This is general information, not medical advice — talk to your doctor or pharmacist about whether ergotamine tartrate is right for you and about any medications or supplements you're currently taking.

Sources & accuracy

This Ergotamine Tartrate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ergotamine Tartrate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.