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Triamcinolone Acetonide Vial — prescription drug image

Triamcinolone Acetonide

Kenalog-40 1ML of 40MG/ML

Prescriptions & Refills
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What is Triamcinolone Acetonide?

Kenalog is a corticosteroid spray used to treat itching, swelling, inflammation and other discomforts of the skin. Triamcinolone topical is the generic version. On average Kenalog is priced at about $676 for 63 grams, 0.147 mg/g topical spray. Luckily, you can use our Rx.com savings offer to receive a Kenalog discount of up to 80% off the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Triamcinolone Acetonide ?

Kenalog is a corticosteroid spray used to treat itching, swelling, inflammation and other discomforts of the skin. Triamcinolone topical is the generic version. On average Kenalog is priced at about $676 for 63 grams, 0.147 mg/g topical spray. Luckily, you can use our Rx.com savings offer to receive a Kenalog discount of up to 80% off the retail price at participating pharmacies near you.
  • Severe headache or pain behind your eyes.
  • Stopping of heart, no blood pressure or pulse, or unconsciousness.
  • Dry mouth, increased thirst, muscle cramps, nausea, or vomiting.
  • Chest pain or discomfort.
  • Change in how much or how often you urinate.
  • Bloody or black, tarry stools.
  • Blurred vision or changes in vision.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, slow, pounding, or uneven heartbeat.
  • Fever, chills, cough, sore throat, and body aches.
  • Muscle weakness or cramps, or sudden joint pain.
  • Numbness or weakness in your arm or leg, or on one side of your body.
  • Shortness of breath, cold sweat, or bluish-colored skin.
  • Swelling in your hands, ankles, or feet.
  • Unusual bleeding, bruising, or weakness.
  • Slowed growth in children.
  • Vomiting of blood or material that looks like coffee grounds.
  • Seizures.
  • Vomiting of blood or material that looks like coffee grounds.
  • Unusual bleeding, bruising, or weakness.
  • Swelling in your hands, ankles, or feet.
  • Stopping of heart, no blood pressure or pulse, or unconsciousness.
  • Slowed growth in children.
  • Shortness of breath, cold sweat, or bluish-colored skin.
  • Severe headache or pain behind your eyes.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • This medicine contains benzyl alcohol that may cause problems (such as low blood pressure and metabolic acidosis) when given too much especially to newborn babies.
  • Let your doctor know if you have any events causing unusual stress or anxiety in your life. Your dose of this medicine may need to be changed.
  • It may be easier for you to get an infection while you are receiving triamcinolone. Avoid crowded places or being near people who are sick. If you are exposed to chicken pox or measles, tell your doctor right away.
  • Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and for patients who use large amounts for a long time. Talk to your doctor if you have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, pounding, or uneven heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.
  • This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. You will be observed for signs and symptoms of anaphylaxis after you receive this medicine. Tell your doctor right away about any unusual effects you may have.
  • Make sure your doctor knows if you have heart disease, congestive heart failure, high blood pressure, or a recent heart attack. Tell your doctor if you have certain infections (such as amoebiasis or candidiasis), viral infections, cerebral malaria, or threadworm infestation.
  • Make sure your doctor knows if you have kidney disease, liver disease, diabetes, tuberculosis, stomach or bowel problems, cataracts, glaucoma, or herpes simplex infection in your eyes. Tell your doctor if you have a mental condition, bone problems (such as osteoporosis), myasthenia gravis, or a thyroid disorder.
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have recently spent time in a tropical climate.
What is Kenalog-40 used for?
Kenalog-40 (triamcinolone acetonide 40 mg/mL) is an injectable corticosteroid given into a muscle or a joint/soft tissue. Into a muscle, it controls severe or incapacitating allergic conditions that have not responded to usual treatment (such as asthma, atopic and contact dermatitis, drug hypersensitivity reactions, allergic rhinitis, serum sickness, and transfusion reactions) and certain serious skin diseases like pemphigus and severe erythema multiforme. Into a joint or soft tissue, it is used for conditions such as acute gouty arthritis, bursitis, tenosynovitis, epicondylitis, rheumatoid arthritis, synovitis, and osteoarthritis.
How long does a Kenalog-40 injection last in your system?
Kenalog-40 is a long-acting ("depot") corticosteroid suspension, meaning the medicine is released slowly from the injection site over an extended period rather than all at once. How long the effect and the drug last varies by the dose, the injection site, and the person, so your provider can give you the best estimate for your situation. Because effects can be prolonged, the dose is tapered after long-term therapy to let your body's own steroid production recover.
What are the side effects of a Kenalog-40 shot?
Possible effects, especially with prolonged use, include increased risk of infection, high blood sugar, high blood pressure, fluid and electrolyte changes, suppression of the body's own steroid production, Cushingoid features, osteoporosis, avascular necrosis, cataracts or glaucoma, mood or psychiatric changes, and growth suppression in children. A joint injection can cause a post-injection flare or, less commonly, a joint infection. Allergic (anaphylactoid) reactions have also been reported. Talk with your provider about what to watch for and report anything concerning.
Is Kenalog-40 the same as a cortisone shot?
"Cortisone shot" is a general term people use for a corticosteroid injection. Kenalog-40 is one type of corticosteroid injection; its active ingredient is triamcinolone acetonide rather than cortisone itself. Other injectable steroids such as methylprednisolone (Depo-Medrol) and dexamethasone are also used for similar purposes. So Kenalog-40 falls into the broad "cortisone shot" category, but it is a specific medicine with its own formulation and uses.
Can Kenalog-40 be injected into a joint?
Yes. Kenalog-40 is labeled for intra-articular (into a joint) and soft-tissue injection, in addition to intramuscular use. It is used in joints for conditions such as acute gouty arthritis, rheumatoid arthritis, synovitis, and osteoarthritis. However, it should not be injected into an infected or unstable joint, and joint injection carries a risk of septic arthritis and a temporary post-injection flare. A healthcare provider performs the injection.
How much does Triamcinolone Acetonide cost without insurance?
The price of Triamcinolone Acetonide without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Triamcinolone Acetonide?
Common side effects of Triamcinolone Acetonide may include: Severe headache or pain behind your eyes., Stopping of heart, no blood pressure or pulse, or unconsciousness., Dry mouth, increased thirst, muscle cramps, nausea, or vomiting., Chest pain or discomfort., Change in how much or how often you urinate.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Triamcinolone Acetonide?
Generic versions may be available for Triamcinolone Acetonide. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Triamcinolone Acetonide on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Triamcinolone Acetonide?
The cheapest pharmacy for Triamcinolone Acetonide depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Triamcinolone Acetonide near you.

Triamcinolone Acetonide Coupons & Prices

Kenalog-40 1ML of 40MG/ML

Prescriptions & Refills
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Triamcinolone Acetonide Vial — prescription drug image
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Use the free Rx.com coupon for Kenalog-40 (triamcinolone acetonide injectable suspension, 40 mg/mL) to lower what you pay for this injectable corticosteroid at the pharmacy. Kenalog-40 is given by a healthcare provider into a muscle or a joint to control severe allergic conditions, certain skin diseases, and inflammatory joint and soft-tissue problems. Whether you are uninsured, on Medicare, or your insurance does not cover it, enter your ZIP above to see today's price and print, text, or show your coupon at the counter.

What is Kenalog-40 and how does it work?

Kenalog-40 is the brand name for triamcinolone acetonide, a corticosteroid (glucocorticoid) supplied as a 40 mg/mL injectable suspension. It is designed for intramuscular (into a muscle) and intra-articular or soft-tissue (into a joint, bursa, or tendon sheath) injection only. It is not for intradermal, intravenous, intraocular, epidural, or intrathecal use. Corticosteroids work by calming inflammation and dialing down an overactive immune response.

Given into a muscle, Kenalog-40 is used to control severe or incapacitating allergic conditions that have not responded to conventional treatment, such as asthma, atopic and contact dermatitis, drug hypersensitivity reactions, seasonal or perennial allergic rhinitis, serum sickness, and transfusion reactions, as well as certain serious dermatologic diseases (including pemphigus, bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, and severe erythema multiforme/Stevens-Johnson syndrome). Injected into a joint or soft tissue, it is used for conditions such as acute gouty arthritis, acute and subacute bursitis, acute nonspecific tenosynovitis, epicondylitis, rheumatoid arthritis, synovitis, and osteoarthritis. Your provider decides the dose and injection site based on your condition.

Kenalog-40 cost: manufacturer savings card vs. Rx.com cash coupon

The "Kenalog-40 coupon" search results are usually dominated by manufacturer and pharmacy discount programs. Manufacturer copay savings cards, when a brand offers one, are generally limited to people with commercial (private) insurance and exclude anyone covered by Medicare, Medicaid, or other government plans; their terms and eligibility vary and can change. The Rx.com cash coupon is different: it is a cash-price discount you can use whether you are uninsured, on Medicare, or when a manufacturer card is declined or does not apply. There is no manufacturer savings card tied to Kenalog-40 here, so a cash coupon is often the most practical route.

The biggest savings lever is that a generic is available: triamcinolone acetonide 40 mg/mL is sold as an FDA-approved, substitutable generic. Ask your provider or pharmacist whether generic triamcinolone is right for you, and compare both the brand and generic prices with your Rx.com coupon. To see current pricing, enter your ZIP above to see today's price at pharmacies near you.

Kenalog-40 alternatives and related corticosteroids

Kenalog-40 belongs to a broad family of corticosteroids used for inflammation and allergic conditions. Which one fits depends on the condition, the injection site, and how long an effect is needed. Related options your provider might consider include:

  • Triamcinolone - the generic active ingredient in Kenalog-40.
  • Kenalog-10 - triamcinolone acetonide 10 mg/mL, the lower-concentration form labeled for intralesional and intra-articular use.
  • Zilretta - an extended-release triamcinolone acetonide injection for osteoarthritis knee pain.
  • Depo-Medrol - injectable methylprednisolone acetate, another long-acting injectable steroid.
  • Dexamethasone and prednisone - corticosteroids commonly used by mouth or injection for many of the same inflammatory and allergic conditions.

Note that Aristospan is triamcinolone hexacetonide, a different ester from the acetonide in Kenalog-40, so the two are not interchangeable. Your provider will choose the product and formulation that best matches your needs.

Kenalog-40 safety and side effects

Kenalog-40 has no boxed warning, but there are important precautions. It must not be given intravenously, intradermally, intraocularly, epidurally, or intrathecally; serious neurologic events, including infarction, have been reported when corticosteroids were given by epidural or spinal injection. Corticosteroids can increase your risk of infection and mask its signs, so live vaccines should not be given while you are immunosuppressed. Injection into a joint carries a risk of joint infection (septic arthritis) and a post-injection flare, and Kenalog-40 should not be injected into an infected or unstable joint. Anaphylactoid (allergic) reactions have also been reported.

Prolonged use can lead to suppression of the body's own steroid production (HPA-axis suppression), Cushingoid effects, high blood sugar, high blood pressure, fluid and electrolyte changes, osteoporosis, avascular necrosis, cataracts or glaucoma, mood or other psychiatric changes, and growth suppression in children. After long-term therapy the dose should be tapered gradually to avoid adrenal insufficiency. This is not medical advice; talk with your healthcare provider about the risks and benefits for your situation and report any concerning symptoms promptly.

Sources & accuracy

This Triamcinolone Acetonide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Triamcinolone Acetonide on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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