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Abreva Tube Of Cream — prescription drug image

Abreva

Abreva 2GM of 10%

What is Abreva?

Abreva is an antiviral cream used to treat fever blisters and cold sores caused by herpes simplex. There is not an Abreva generic drug currently available on the U.S. market. On average Abreva is priced at about $24 for 2 grams, 10% topical cream. Luckily, you can use our Rx.com savings offer to receive an Abreva discount of up to 80% off the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Abreva ?

Abreva is an antiviral cream used to treat fever blisters and cold sores caused by herpes simplex. There is not an Abreva generic drug currently available on the U.S. market. On average Abreva is priced at about $24 for 2 grams, 10% topical cream. Luckily, you can use our Rx.com savings offer to receive an Abreva discount of up to 80% off the retail price at participating pharmacies near you.
  • Headache
  • Skin rash or increased redness
  • Make sure your doctor knows if you are pregnant or breastfeeding.
Does Abreva actually get rid of cold sores faster?
Abreva (docosanol 10% cream) is FDA-approved as an over-the-counter treatment shown to shorten the healing time of cold sores and reduce symptoms like tingling, pain, itching, and burning. It works best when applied at the very first sign of an outbreak—tingling, redness, a bump, or itch—rather than after a sore has fully formed.
How often should you apply Abreva and for how long?
The label directs applying Abreva cream 5 times a day to the affected area of the face or lips, continuing until the cold sore is healed. It's approved for adults and children 12 years and older.
Is Abreva the same as Valtrex or acyclovir?
No. Abreva is a topical, over-the-counter cream applied directly to a cold sore on the skin. Valtrex (valacyclovir) and acyclovir (brand name Zovirax) are prescription oral antiviral medications that work systemically to suppress herpes simplex virus and require a doctor's prescription. They're different types of products used differently, though both address the same underlying virus.
Can you use Abreva on a pimple or in the mouth?
No. Abreva is FDA-approved specifically to treat cold sores and fever blisters on the face or lips caused by herpes simplex virus type 1. It is not indicated for pimples, acne, or other skin conditions, and the label directs against use inside the mouth or in the eyes.
Is there a generic version of Abreva (docosanol) that's cheaper?
Docosanol 10% cream, the active ingredient in Abreva, is available as a generic in store-brand and other over-the-counter versions. Prices vary by retailer and pharmacy, so it's worth comparing before you buy—enter your ZIP above to see current prices near you.
How much does Abreva cost without insurance?
The price of Abreva without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Abreva?
Common side effects of Abreva may include: Headache, Skin rash or increased redness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Abreva?
Generic versions may be available for Abreva. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Abreva on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Abreva?
The cheapest pharmacy for Abreva depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Abreva near you.

Abreva Coupons & Prices

Abreva 2GM of 10%

Abreva Tube Of Cream — prescription drug image
Prescription
Abreva 2gm of 10% (0.5)
your area ·

Abreva prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
2gm of 10% · Tube Of Cream 2 $47.17 $27.24

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for an Abreva coupon before you buy? Abreva (docosanol 10% cream) is FDA-approved as an over-the-counter treatment shown to shorten the healing time of cold sores when applied at the very first tingle, and while it doesn't require a prescription, an Rx.com coupon can still help you compare pharmacy prices before you check out—just enter your ZIP above to see today's price near you.

What Abreva Is and How It Works

Abreva's active ingredient is docosanol, a saturated fatty alcohol available in a 10% cream. It's FDA-approved as an over-the-counter treatment for cold sores and fever blisters on the face or lips caused by herpes simplex virus type 1 (HSV-1). It works best when applied topically at the very first sign of an outbreak—tingling, redness, a bump, or itching—and is used 5 times a day on the affected area until the sore heals.

Abreva is approved for adults and children 12 years and older. It is not indicated for genital herpes, and it should not be used inside the mouth or in the eyes.

Comparing Prices and Saving on Abreva

Because Abreva is sold over the counter, you don't need a prescription to buy it, but prices for the same box can still vary quite a bit from one pharmacy to the next. Enter your ZIP code above to compare prices at pharmacies near you before you buy, since some OTC products end up costing less with a coupon than they do off the shelf.

Abreva does not currently offer a manufacturer copay or savings card program the way many prescription brands do; check the official Abreva website directly if you want to confirm current promotions, since terms can change.

Abreva vs. Prescription Antivirals

Abreva is often compared to prescription oral antivirals used for cold sores and other herpes simplex infections, but they work differently. Abreva is a topical cream applied directly to a cold sore on the lip or face to help it heal faster. Prescription antivirals such as valacyclovir (brand name Valtrex), acyclovir (brand name Zovirax), and famciclovir are taken by mouth and work systemically to suppress the herpes virus; they require a doctor's prescription and are used for both cold sores and other HSV infections, including more frequent or severe outbreaks.

Which option makes sense depends on how often you get cold sores and how severe they are—that's a conversation to have with your doctor or pharmacist.

Safety Information

Abreva is for external use only on the face and lips—avoid the eyes and the inside of the mouth. Stop use and talk to a doctor if your cold sore hasn't healed within 10 days, if symptoms persist or get worse, if you develop a fever or rash, if a sore appears near your eyes, or if you get cold sores frequently. The most commonly reported side effect is mild burning or stinging where the cream is applied.

If you have a weakened immune system (for example, due to HIV or cancer treatment), ask a doctor before using Abreva. This information is not a substitute for medical advice—talk with your doctor or pharmacist about your specific situation.

Sources & accuracy

This Abreva information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Abreva on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.