Addyi
Addyi
What is Addyi?
Addyi (flibanserin) is a prescription medication approved to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in certain premenopausal women. It works by affecting brain chemicals involved in sexual desire and may help increase sexual interest over time when taken consistently.
Side Effects
- Sleepiness or unusual drowsiness
- Dry mouth
- Nausea
Warnings
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you or for 6 hours after you take a dose. Sit or lie down if you feel dizzy or lightheaded. Tell your doctor if you continue to feel dizzy or lightheaded after you have been using this medicine for awhile.
- Call your doctor if your symptoms do not improve within 8 weeks, or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Do not breastfeed while you are using this medicine.
- Tell your doctor if you are pregnant, or if you have low blood pressure or a history of depression, mental problems, or alcohol or drug abuse.
Prescription savings · · · ·
What is Addyi ?
Addyi (flibanserin) is a prescription medication approved to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in certain premenopausal women. It works by affecting brain chemicals involved in sexual desire and may help increase sexual interest over time when taken consistently.
- Sleepiness or unusual drowsiness
- Dry mouth
- Nausea
- Tiredness
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you or for 6 hours after you take a dose. Sit or lie down if you feel dizzy or lightheaded. Tell your doctor if you continue to feel dizzy or lightheaded after you have been using this medicine for awhile.
- Call your doctor if your symptoms do not improve within 8 weeks, or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Do not breastfeed while you are using this medicine.
- Tell your doctor if you are pregnant, or if you have low blood pressure or a history of depression, mental problems, or alcohol or drug abuse.
Addyi Coupons & Prices
Addyi
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours
Looking for an Addyi coupon? Addyi (flibanserin) is a once-daily, FDA-approved prescription pill for acquired, generalized hypoactive sexual desire disorder (HSDD) — low sexual desire that causes marked distress. It is a brand-name-only medication and can be expensive at the pharmacy counter, so the price you pay matters. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you, and read on to compare that cash coupon with the manufacturer's savings card so you can pick whichever costs you less.
What is Addyi and how does it work?
Addyi (flibanserin) is a centrally acting medication that works on brain chemistry rather than on blood flow. It is a multifunctional serotonin agonist/antagonist — it acts as a serotonin 5-HT1A receptor agonist and a 5-HT2A receptor antagonist. It is FDA-approved to treat acquired, generalized hypoactive sexual desire disorder (HSDD): low sexual desire that causes marked distress or relationship difficulty and is not explained by another medical or psychiatric condition, relationship problems, or the effects of another medication.
Addyi was originally approved in 2015 for premenopausal women. In December 2025, the FDA broadened the approval so that the indication now covers women younger than 65 years with acquired, generalized HSDD — both premenopausal and postmenopausal. It is taken as one 100 mg tablet once daily at bedtime. Bedtime dosing is important because it lowers the risk of low blood pressure, fainting, accidental injury, and daytime drowsiness. Addyi is not for enhancing sexual performance and is not indicated in men.
Addyi cost: manufacturer savings card vs. Rx.com cash coupon
Because Addyi is a brand-name medication with no generic currently available, the price can be high, and how you pay makes a real difference. There are two main ways to save, and they work in different situations:
- Manufacturer savings card. The maker of Addyi offers a savings program. Copay/savings cards like this are generally limited to people with commercial (private) insurance and typically exclude government coverage such as Medicare or Medicaid. Terms, eligibility, and any dollar limits vary and change over time — check the official page at addyi.com/getting-addyi for current details.
- Rx.com cash coupon. Our free cash coupon is useful when the manufacturer card doesn't apply — for example if you are uninsured, have Medicare or Medicaid, or your card is declined. It is a cash price, so it doesn't run through insurance. Enter your ZIP above to see today's Rx.com price at pharmacies near you.
The simplest approach: compare the manufacturer card and the Rx.com cash coupon and use whichever costs you less at your pharmacy. We don't list dollar figures here because prices change constantly and are shown live above.
Addyi alternatives and how it compares
Addyi is often confused with erectile-dysfunction pills, but it is not "female Viagra." ED pills work on blood flow and are taken as needed; Addyi works on brain chemistry and is taken every day to gradually raise sexual desire in women with HSDD.
Within HSDD treatment, the main alternative is Vyleesi (bremelanotide), an injectable that is used on demand before anticipated sexual activity rather than taken daily. Addyi's active ingredient is also known by its generic name, flibanserin. Which option fits you depends on your health history and preferences — this is a conversation to have with your prescriber. Whichever you and your provider choose, you can enter your ZIP above to compare current cash prices.
Addyi safety: what to know before you start
Addyi carries an FDA boxed warning for low blood pressure (hypotension) and fainting (syncope). Because of this, three things are especially important: (1) drinking alcohol close in time to your dose raises the risk of severe low blood pressure and fainting; (2) it should not be combined with moderate or strong CYP3A4 inhibitors (certain other medicines), which is contraindicated; and (3) it should not be used by people with liver (hepatic) impairment, which is also contraindicated. Talk with your prescriber and pharmacist about your other medicines, liver health, and alcohol use before you start.
The most common side effects include dizziness, sleepiness, nausea, tiredness, trouble sleeping, and dry mouth. The effect on desire is modest and takes about 8 weeks to appear; if there is no improvement by 8 weeks, providers generally stop the medication. This is general information, not medical advice — talk with your doctor or pharmacist about your health history, other medications, and alcohol use before starting Addyi.
This Addyi information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Addyi on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with A · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.