Apokyn Coupons & Prices

Looking for an Apokyn coupon? Apokyn (apomorphine hydrochloride) is a prescription "rescue" injection used to quickly treat sudden "off" episodes of stiffness and slowness in people with advanced Parkinson's disease. Because it is a brand-name specialty drug, the out-of-pocket cost can be high, but you have options. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you, and read on to compare the Rx.com coupon with the manufacturer's savings program and with lower-cost generic apomorphine.

What is Apokyn and how does it work?

Apokyn is the brand name for apomorphine hydrochloride, a non-ergoline dopamine agonist. It is FDA-approved for the acute, intermittent treatment of hypomobility, or "off" episodes, in people with advanced Parkinson's disease. That includes both end-of-dose "wearing off" and the more unpredictable "on/off" swings. Apokyn works by stimulating dopamine receptors in the brain, helping restore movement during an off episode.

Apokyn is given as a subcutaneous (under-the-skin) injection using the multiple-dose Apokyn Pen. It is a rescue therapy for breakthrough symptoms, not a scheduled maintenance medicine, so it is used alongside your regular Parkinson's drugs rather than replacing them. It should never be given intravenously. A related sublingual apomorphine film, Kynmobi, treats the same off episodes for people who prefer an under-the-tongue option instead of an injection.

Apokyn cost, coupons, and savings options

As a brand-name specialty injectable, Apokyn can be expensive without help. There are three main ways people lower the cost:

• Rx.com cash coupon: Our free coupon gives you a cash price you can use even if you are uninsured, on Medicare, or if a manufacturer card is declined. Enter your ZIP above to see today's price at pharmacies near you, then show the coupon at the pharmacy counter.
• Manufacturer savings card: The maker of Apokyn runs an official copay savings program, described on the manufacturer's site at apokyn.com. Like most brand copay cards, it is generally limited to people with commercial (non-government) insurance and is not available to those on Medicare, Medicaid, or other federal plans. Terms, eligibility, and any caps vary and change over time, so check the current details directly. Manufacturers of specialty Parkinson's drugs often also offer a patient-assistance program for qualifying uninsured or low-income patients; ask your prescriber or the manufacturer whether you qualify.
• Generic apomorphine: This is usually the biggest savings lever. A generic apomorphine hydrochloride injection is FDA-approved and available in the US. It contains the same active ingredient as Apokyn, and asking your prescriber and pharmacist whether the generic is appropriate for you can lower your cost considerably. Enter your ZIP above to compare the cash price on the generic as well.

Alternatives and related Parkinson's medicines

Apokyn is a rescue treatment for off episodes, so it is typically used with other Parkinson's therapies rather than instead of them. Depending on your symptoms and how your care team manages your treatment, related options include:

• Kynmobi (sublingual apomorphine film) — another as-needed rescue option for off episodes.
• Inbrija (inhaled levodopa) — an inhaled rescue therapy for off episodes.
• Carbidopa-levodopa — the foundational scheduled Parkinson's therapy that off episodes occur between.
• Oral dopamine agonists such as pramipexole and ropinirole, or the rotigotine transdermal patch.

These medicines differ in how and when they are used. Only your prescriber can decide which combination fits your Parkinson's disease, so use this list to start a conversation, not to self-adjust your regimen.

Important safety information

Apokyn does not carry a boxed warning, but it has serious safety considerations. Most importantly, Apokyn must not be used with 5-HT3 antagonist antiemetics such as ondansetron, granisetron, dolasetron, palonosetron, or alosetron, because the combination can cause profound drops in blood pressure and loss of consciousness. It is also contraindicated in people with a known allergy to apomorphine or to sodium metabisulfite. Apokyn commonly causes nausea and vomiting, so the antiemetic trimethobenzamide is usually recommended before and during early treatment.

Other important risks include a sudden drop in blood pressure when standing (orthostatic hypotension) and fainting, falling asleep suddenly during daily activities, hallucinations or confusion, impulse-control problems (such as gambling, compulsive spending, or hypersexuality), QT-interval prolongation, prolonged painful erections (priapism), injection-site reactions, dyskinesia, and heart or stroke-related events. Do not stop or abruptly lower your dose on your own, as this can trigger a serious withdrawal reaction. This is general information, not medical advice. Tell your provider about all your medicines and health conditions, and review the full FDA label with your care team before starting Apokyn.