Apraclonidine Hcl
Apraclonidine HCl 5ML of 0.5%
What is Apraclonidine Hcl?
Iopidine is a prescription medicine used to treat glaucoma. Apraclonidine ophthalmic is the generic version of Iopidine. The average price of Iopidine is around $183 for a supply of 5 ml, 0.5% ophthalmic solution. Use our Rx.com savings offer to get an average Iopidine discount of up to 80% at participating pharmacies near you.Side Effects
- Slow, pounding, or uneven heartbeat
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, high blood pressure, heart or blood vessel disease (including Raynaud disease, thromboangiitis obliterans), or a history of heart attack or stroke.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Lightheadedness or fainting
Prescription savings · · · ·
What is Apraclonidine Hcl ?
Iopidine is a prescription medicine used to treat glaucoma. Apraclonidine ophthalmic is the generic version of Iopidine. The average price of Iopidine is around $183 for a supply of 5 ml, 0.5% ophthalmic solution. Use our Rx.com savings offer to get an average Iopidine discount of up to 80% at participating pharmacies near you.- Slow, pounding, or uneven heartbeat
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision
- Dizziness, lightheadedness or fainting
- Eye redness, burning, itching, or discomfort
- Fast, pounding, or uneven heartbeat
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, high blood pressure, heart or blood vessel disease (including Raynaud disease, thromboangiitis obliterans), or a history of heart attack or stroke.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Lightheadedness or fainting
- Slow, pounding, or uneven heartbeat
Apraclonidine Hcl Coupons & Prices
Apraclonidine HCl 5ML of 0.5%
Apraclonidine hydrochloride is a prescription eye drop your ophthalmologist may use around the time of laser eye surgery to keep eye pressure from spiking, and pharmacy cash prices for it can vary. If you're comparing an apraclonidine coupon, enter your ZIP code above to see prices at pharmacies near you.
What is apraclonidine and how does it work?
Apraclonidine is an alpha-2 adrenergic agonist eye drop. Its 1% ophthalmic solution is indicated for the prevention and control of elevated intraocular pressure (IOP) that can occur after certain laser eye procedures, such as laser trabeculoplasty or iridotomy. It's typically given as a single drop shortly before the procedure and another drop afterward, under an eye doctor's direction.
Comparing prices for apraclonidine
Apraclonidine is available as a generic apraclonidine hydrochloride ophthalmic solution. Because it's often a short-course, one-off prescription tied to a procedure, prices can differ noticeably by pharmacy. Rx.com compares prices across more than 60,000 U.S. pharmacies so you can find a lower cash price, whether or not you have insurance.
Related glaucoma and eye-pressure medicines
- Brimonidine — another alpha-2 agonist eye drop, more commonly used for ongoing glaucoma management rather than a single perioperative dose.
- Timolol — a beta-blocker eye drop often used for long-term IOP control.
- Latanoprost — a prostaglandin analog commonly used as a first-line, once-daily glaucoma treatment.
Apraclonidine's approved use is centered on short-term IOP spikes around laser procedures, so your eye doctor will choose a different medicine if you need ongoing pressure control.
Safety information
Apraclonidine drops can cause local eye irritation, dry mouth, or drowsiness in some people, and effects tend to lessen with repeated, longer-term use, which is one reason it's used for short courses around procedures rather than daily long-term therapy. It should be used cautiously in people with cardiovascular disease and those taking certain other blood-pressure or mood medicines. This isn't a complete list of warnings; follow your eye doctor's instructions and ask your pharmacist about any interactions with your other medicines.
This Apraclonidine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Apraclonidine Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.