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Apri Disp Pack — prescription drug image

Apri

Apri 28 Tablets

Prescriptions & Refills
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What is Apri?

Juleber is used to prevent pregnancy. Desogestrel-Ethinyl Estradiol is the generic version of Juleber. On average, the price of Juleber is about $119 for a supply of 168, 0.15 mg-0.03 mg tablets. You can use our free Singlecare savings card to receive a Juleber discount of up to 80% at any local participating pharmacy.

Prescription savings · · · ·

What is Apri ?

Juleber is used to prevent pregnancy. Desogestrel-Ethinyl Estradiol is the generic version of Juleber. On average, the price of Juleber is about $119 for a supply of 168, 0.15 mg-0.03 mg tablets. You can use our free Singlecare savings card to receive a Juleber discount of up to 80% at any local participating pharmacy.
  • Sudden and severe stomach pain, nausea, vomiting, lightheadedness
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Vision loss, double vision
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Breast changes or lumps
  • Chest pain that may spread, unusual sweating, fainting
  • Dark urine or pale stools, loss of appetite, yellow skin or eyes
  • Numbness or weakness on one side of your body, pain in your lower leg (calf), sudden or severe headache, problems with vision, speech, or walking
  • Heavy vaginal bleeding, irregular or missed menstrual period
  • Trouble breathing, coughing up blood
  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
  • Tell your doctor if you are breastfeeding, or if you had a baby within 4 to 6 weeks before you start using this medicine. Tell your doctor if you have kidney disease, diabetes, epilepsy, migraine headaches, heart or blood vessel disease, high cholesterol, high blood pressure, a family history of breast cancer, or a personal history of cervical cancer, or depression. Tell your doctor if you smoke cigarettes.
  • This medicine may cause the following problems: Increased risk of heart attack, stroke, or blood clots (which is more likely when you first start taking birth control pills or when starting again after not using them for at least a month)Possible increased risk of breast or cervical cancerLiver problems (including liver cancer or tumors)Eye or vision problemsGallbladder diseaseHigh cholesterol in the bloodHigh blood pressureIncreased risk of ectopic pregnancy (pregnancy outside the uterus)
  • This medicine will not protect you from HIV/AIDS or other sexually transmitted infections.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Apri used for?
Apri is a combination birth control pill that is FDA-approved to prevent pregnancy in women who choose to use oral contraceptives. It works mainly by preventing ovulation, thickening cervical mucus, and changing the uterine lining. Some providers also prescribe combination pills like Apri to help regulate periods, ease heavy or painful periods, treat acne, or reduce premenstrual symptoms.
Is Apri the same as Desogen?
Apri is a generic version of Desogen. Both contain the same active ingredients at the same strengths: 0.15 mg desogestrel and 0.03 mg ethinyl estradiol in each active tablet. Other names for the same combination include Enskyce, Reclipsen, Ortho-Cept, Emoquette, and Cyred.
How effective is Apri at preventing pregnancy?
Combination birth control pills like Apri are highly effective at preventing pregnancy when taken correctly and consistently every day. Effectiveness drops with missed or late doses, and can also be reduced by certain other medicines such as some antibiotics and anticonvulsants. Apri does not protect against HIV or other sexually transmitted infections. Your provider can advise on how to use it most effectively.
What are the side effects of Apri?
Like all combination oral contraceptives, Apri can raise the risk of serious problems such as blood clots, stroke, and heart attack, and this risk is higher for smokers and women over 35 who smoke. It should not be used by people with certain conditions such as a history of blood clots, certain migraines, uncontrolled high blood pressure, estrogen-dependent cancers, or liver disease. Discuss your full health history and any side effects with your healthcare provider.
What should I do if I miss a dose of Apri?
Missing doses lowers how well Apri prevents pregnancy. The right steps depend on how many pills you missed and where you are in your pack, so follow the instructions in the package insert and contact your pharmacist or provider if you are unsure. You may need to use a backup method of birth control. Do not stop or change your pills without guidance from your healthcare provider.
How much does Apri cost without insurance?
The price of Apri without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 34% off retail prices with a free Rx.com coupon.
What are the common side effects of Apri?
Common side effects of Apri may include: Sudden and severe stomach pain, nausea, vomiting, lightheadedness, Rapid weight gain, swelling in your hands, ankles, or feet, Vision loss, double vision, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Breast changes or lumps. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Apri?
Generic versions may be available for Apri. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Apri on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Apri?
The cheapest pharmacy for Apri depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Apri near you.

Apri Coupons & Prices

Apri 28 Tablets

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Apri Disp Pack — prescription drug image
Prescription
Apri 1 package (28 tablets), 0.15-30mg-mcg (1)
your area ·
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for an Apri coupon? Rx.com offers a free cash-price discount coupon for Apri (desogestrel and ethinyl estradiol), a combination birth control pill used to prevent pregnancy. Our coupon works at the pharmacy counter whether or not you have insurance, and it applies to the lower-cost generic versions too. Enter your ZIP code above to see today's price at pharmacies near you.

What is Apri and how does it work?

Apri is a monophasic combination oral contraceptive. Each active rose-colored tablet contains 0.15 mg of the progestin desogestrel and 0.03 mg of the synthetic estrogen ethinyl estradiol. A 28-day pack holds 21 active tablets plus 7 inert (reminder) tablets. Like other combination pills, Apri prevents pregnancy in three ways: it suppresses ovulation so an egg is not released, it thickens cervical mucus to help block sperm, and it changes the lining of the uterus.

Apri is FDA-approved for the prevention of pregnancy in women who choose to use oral contraceptives. Some providers also prescribe combination pills like this one to help regulate menstrual cycles, ease heavy or painful periods, manage acne, or reduce premenstrual symptoms. Whether Apri is right for you is a decision to make with your healthcare provider.

Apri cost: manufacturer savings vs. the Rx.com cash coupon

The single biggest way to save on Apri is the generic. Apri itself is a generic version of the brand Desogen, and desogestrel/ethinyl estradiol is sold under many names including Enskyce, Reclipsen, Emoquette, Cyred, Isibloom, Juleber, and Solia. Because there is no brand-only version to pay for, cash prices are often very affordable. There is no manufacturer copay savings card for Apri, and manufacturer savings cards in general are typically limited to people with commercial (non-government) insurance, with terms that vary.

The Rx.com cash coupon is a good fit when you are uninsured, on Medicare or Medicaid (which cannot use manufacturer copay cards), or when a card is declined at the counter. It sets a discounted cash price you can simply show your pharmacist. If cost is a barrier, it is also worth asking your provider or pharmacist about lower-cost equivalents. Enter your ZIP above to see today's Apri price near you.

Apri alternatives and equivalents

Apri is one of several interchangeable desogestrel/ethinyl estradiol pills. If your pharmacy is out of stock or another version is cheaper, these contain the same active ingredients at the same strengths:

Related desogestrel pills such as Kariva and Mircette use a slightly different formulation and dosing schedule, so they are similar but not direct substitutes. Do not switch pills without talking to your provider or pharmacist, since dosing and packaging can differ.

Important safety information

This is general information, not medical advice. Talk with your healthcare provider before starting or changing Apri. Apri carries a boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives, and that risk rises with age and with heavier smoking. Women over 35 who smoke should not use combination birth control pills. Combination pills also carry an increased risk of blood clots (venous thromboembolism), stroke, heart attack, and pulmonary embolism.

Apri is not for everyone. It should not be used during pregnancy or by people with a current or past history of blood clots, certain migraines, uncontrolled high blood pressure, estrogen-dependent cancers (including breast cancer), liver disease or liver tumors, or undiagnosed abnormal vaginal bleeding. Importantly, Apri does NOT protect against HIV or other sexually transmitted infections. Its effectiveness can be reduced by missed doses and by certain other medicines, including some antibiotics and anticonvulsants, so tell your provider about everything you take.

Sources & accuracy

This Apri information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Apri on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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