Apri
Apri 28 Tablets
What is Apri?
Juleber is used to prevent pregnancy. Desogestrel-Ethinyl Estradiol is the generic version of Juleber. On average, the price of Juleber is about $119 for a supply of 168, 0.15 mg-0.03 mg tablets. You can use our free Singlecare savings card to receive a Juleber discount of up to 80% at any local participating pharmacy.Side Effects
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Rapid weight gain, swelling in your hands, ankles, or feet
- Vision loss, double vision
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you had a baby within 4 to 6 weeks before you start using this medicine. Tell your doctor if you have kidney disease, diabetes, epilepsy, migraine headaches, heart or blood vessel disease, high cholesterol, high blood pressure, a family history of breast cancer, or a personal history of cervical cancer, or depression. Tell your doctor if you smoke cigarettes.
- This medicine may cause the following problems: Increased risk of heart attack, stroke, or blood clots (which is more likely when you first start taking birth control pills or when starting again after not using them for at least a month)Possible increased risk of breast or cervical cancerLiver problems (including liver cancer or tumors)Eye or vision problemsGallbladder diseaseHigh cholesterol in the bloodHigh blood pressureIncreased risk of ectopic pregnancy (pregnancy outside the uterus)
- This medicine will not protect you from HIV/AIDS or other sexually transmitted infections.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
Prescription savings · · · ·
What is Apri ?
Juleber is used to prevent pregnancy. Desogestrel-Ethinyl Estradiol is the generic version of Juleber. On average, the price of Juleber is about $119 for a supply of 168, 0.15 mg-0.03 mg tablets. You can use our free Singlecare savings card to receive a Juleber discount of up to 80% at any local participating pharmacy.- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Rapid weight gain, swelling in your hands, ankles, or feet
- Vision loss, double vision
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Breast changes or lumps
- Chest pain that may spread, unusual sweating, fainting
- Dark urine or pale stools, loss of appetite, yellow skin or eyes
- Numbness or weakness on one side of your body, pain in your lower leg (calf), sudden or severe headache, problems with vision, speech, or walking
- Heavy vaginal bleeding, irregular or missed menstrual period
- Trouble breathing, coughing up blood
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you had a baby within 4 to 6 weeks before you start using this medicine. Tell your doctor if you have kidney disease, diabetes, epilepsy, migraine headaches, heart or blood vessel disease, high cholesterol, high blood pressure, a family history of breast cancer, or a personal history of cervical cancer, or depression. Tell your doctor if you smoke cigarettes.
- This medicine may cause the following problems: Increased risk of heart attack, stroke, or blood clots (which is more likely when you first start taking birth control pills or when starting again after not using them for at least a month)Possible increased risk of breast or cervical cancerLiver problems (including liver cancer or tumors)Eye or vision problemsGallbladder diseaseHigh cholesterol in the bloodHigh blood pressureIncreased risk of ectopic pregnancy (pregnancy outside the uterus)
- This medicine will not protect you from HIV/AIDS or other sexually transmitted infections.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Apri Coupons & Prices
Apri 28 Tablets
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for an Apri coupon? Rx.com offers a free cash-price discount coupon for Apri (desogestrel and ethinyl estradiol), a combination birth control pill used to prevent pregnancy. Our coupon works at the pharmacy counter whether or not you have insurance, and it applies to the lower-cost generic versions too. Enter your ZIP code above to see today's price at pharmacies near you.
What is Apri and how does it work?
Apri is a monophasic combination oral contraceptive. Each active rose-colored tablet contains 0.15 mg of the progestin desogestrel and 0.03 mg of the synthetic estrogen ethinyl estradiol. A 28-day pack holds 21 active tablets plus 7 inert (reminder) tablets. Like other combination pills, Apri prevents pregnancy in three ways: it suppresses ovulation so an egg is not released, it thickens cervical mucus to help block sperm, and it changes the lining of the uterus.
Apri is FDA-approved for the prevention of pregnancy in women who choose to use oral contraceptives. Some providers also prescribe combination pills like this one to help regulate menstrual cycles, ease heavy or painful periods, manage acne, or reduce premenstrual symptoms. Whether Apri is right for you is a decision to make with your healthcare provider.
Apri cost: manufacturer savings vs. the Rx.com cash coupon
The single biggest way to save on Apri is the generic. Apri itself is a generic version of the brand Desogen, and desogestrel/ethinyl estradiol is sold under many names including Enskyce, Reclipsen, Emoquette, Cyred, Isibloom, Juleber, and Solia. Because there is no brand-only version to pay for, cash prices are often very affordable. There is no manufacturer copay savings card for Apri, and manufacturer savings cards in general are typically limited to people with commercial (non-government) insurance, with terms that vary.
The Rx.com cash coupon is a good fit when you are uninsured, on Medicare or Medicaid (which cannot use manufacturer copay cards), or when a card is declined at the counter. It sets a discounted cash price you can simply show your pharmacist. If cost is a barrier, it is also worth asking your provider or pharmacist about lower-cost equivalents. Enter your ZIP above to see today's Apri price near you.
Apri alternatives and equivalents
Apri is one of several interchangeable desogestrel/ethinyl estradiol pills. If your pharmacy is out of stock or another version is cheaper, these contain the same active ingredients at the same strengths:
Related desogestrel pills such as Kariva and Mircette use a slightly different formulation and dosing schedule, so they are similar but not direct substitutes. Do not switch pills without talking to your provider or pharmacist, since dosing and packaging can differ.
Important safety information
This is general information, not medical advice. Talk with your healthcare provider before starting or changing Apri. Apri carries a boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives, and that risk rises with age and with heavier smoking. Women over 35 who smoke should not use combination birth control pills. Combination pills also carry an increased risk of blood clots (venous thromboembolism), stroke, heart attack, and pulmonary embolism.
Apri is not for everyone. It should not be used during pregnancy or by people with a current or past history of blood clots, certain migraines, uncontrolled high blood pressure, estrogen-dependent cancers (including breast cancer), liver disease or liver tumors, or undiagnosed abnormal vaginal bleeding. Importantly, Apri does NOT protect against HIV or other sexually transmitted infections. Its effectiveness can be reduced by missed doses and by certain other medicines, including some antibiotics and anticonvulsants, so tell your provider about everything you take.
This Apri information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Apri on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Related Drugs
Browse more medications: starting with A · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.