What is Bupivacaine-Epinephrine ?

Bupivacaine-Epinephrine is a sterile solution combining bupivacaine hydrochloride, a long-acting local anesthetic, with epinephrine, a vasoconstrictor that prolongs anesthetic effects and reduces systemic absorption. This formulation is used to provide regional anesthesia for surgical, obstetrical, or diagnostic procedures while minimizing blood loss and enhancing the duration of pain control. Its use should be carefully monitored due to potential cardiovascular side effects associated with both active components.

• Lightheadedness, dizziness, or fainting
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Anxiety, depression, restlessness, drowsiness, ringing in your ears, blurred vision
• Nausea, vomiting, chills, metallic taste in your mouth
• Seizures, shivering, shaking, or tremors
• Chest pain, fast, pounding, slow, or uneven heartbeat, trouble breathing
• Pale, gray, or blue lips, nails, or skin, dark urine, headache, unusual tiredness or weakness

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, high blood pressure, low blood pressure, lung or breathing problems, a blood disorder, G6PD, atherosclerosis (hardening of the arteries), other circulation problems, diabetes, asthma, thyroid problems, or a history of stroke. Tell your doctor if you have a sulfite allergy.
• This medicine may cause methemoglobinemia (blood disorder).
• You may experience temporary loss of sensation and movement, usually in the lower half of your body, if you receive this medicine into your lower back (epidural). It may be easier to hurt yourself while your treated body area is still numb. Be careful to avoid injury until you have regained all the feeling and are no longer numb.
• To avoid injury after dental work, do not chew solid foods until normal feeling has returned to the area. Do not test the feeling in your mouth by biting or poking the treated area (up to 7 hours).
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Seizures, shivering, shaking, or tremors