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Digoxin

Digoxin 125MCG

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What is Digoxin?

Digitek is a prescription medication used to treat heart failure. Digoxin is the generic version of Digitek. The average price for Digitek is around $85 for a supply of 30, 0.125 mg capsules. Use our Rx.com savings offer to get great discounts on Digitek at participating pharmacies near you.

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What is Digoxin ?

Digitek is a prescription medication used to treat heart failure. Digoxin is the generic version of Digitek. The average price for Digitek is around $85 for a supply of 30, 0.125 mg capsules. Use our Rx.com savings offer to get great discounts on Digitek at participating pharmacies near you.
  • Confusion, tiredness or weakness, trouble breathing, numbness or tingling in hands, feet, or lips
  • Unusual behavior, stomach pain, or weight loss (in children)
  • Fast, slow, or uneven heartbeat
  • Changes in vision
  • Nausea, vomiting, diarrhea, loss of appetite
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Make sure your doctor knows if you are pregnant or breastfeeding or if you have kidney disease, heart or blood vessel problems, breathing problems (such as hypoxia), mineral imbalances (such as high or low calcium, or low potassium or magnesium in the blood), or thyroid problems. Tell your doctor if you are on dialysis, have had a recent heart attack, or if you have recently been vomiting or had diarrhea.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Watch for signs and symptoms of overdose while you are taking this medicine. Follow your doctor's directions carefully. The amount of this medicine needed to help most people is very close to the amount that could cause serious problems from overdose. Some early warning signs of overdose are confusion, loss of appetite, nausea, vomiting, diarrhea, or vision problems. Other signs of overdose are an uneven, pounding, or slow heartbeat or fainting. In babies and small children, the earliest signs of overdose are heartbeat changes, weight loss, stomach pain, or unusual behavior.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Nausea, vomiting, diarrhea, loss of appetite
  • Unusual behavior, stomach pain, or weight loss (in children)
What is digoxin used for?
Digoxin is FDA-approved to treat mild to moderate heart failure in adults, where it can improve exercise capacity and reduce heart-failure hospitalizations when added to standard therapy such as diuretics, ACE inhibitors or ARBs, and beta-blockers. It is also approved to increase heart-muscle contractility in children with heart failure, and to control the ventricular rate in adults with chronic atrial fibrillation. It does not restore a normal heart rhythm and has not been shown to reduce mortality, and for rate control it is generally used after beta-blockers and non-dihydropyridine calcium channel blockers.
What are the signs of digoxin toxicity?
Digoxin has a narrow therapeutic index, meaning toxicity can occur even at ordinary doses. Warning signs include nausea, vomiting, loss of appetite, diarrhea, confusion, dizziness, and weakness; visual disturbances such as blurred vision or seeing yellow or green tints or halos; and a heartbeat that is slow, fast, or irregular. Low potassium, low magnesium, high calcium, reduced kidney function, and older age all increase the risk. Contact your prescriber promptly if you notice these symptoms, and get emergency care for fainting or a very slow or very irregular pulse.
What foods, supplements, and medications should you avoid while taking digoxin?
Digoxin has many important drug interactions. Tell your prescriber and pharmacist about everything you take, especially amiodarone, verapamil, quinidine, clarithromycin or erythromycin, itraconazole, cyclosporine, propafenone, spironolactone, and diuretics that lower potassium. Anything that throws off your electrolytes matters, because low potassium, low magnesium, or high calcium raise the risk of digoxin toxicity, so do not start potassium, magnesium, or calcium supplements (or antacids containing them) without asking first. Your doctor will monitor your potassium, kidney function, and sometimes your serum digoxin level.
When should you not take digoxin, and should you check your pulse first?
Many prescribers teach patients on digoxin how to take their own pulse and give a heart-rate threshold below which they should hold the dose and call the office; ask your prescriber whether that applies to you and what your number is. Digoxin is contraindicated in ventricular fibrillation and in anyone hypersensitive to digoxin or digitalis, and it can cause severe slow heart rate or advanced heart block in people with sinus node disease or existing AV block. It can be dangerous in atrial fibrillation with an accessory pathway (Wolff-Parkinson-White), and it is not recommended in acute heart attack or myocarditis. Do not stop digoxin on your own without talking to your prescriber.
Is digoxin the same as Lanoxin, and is there a generic?
Yes. Lanoxin is the brand name and digoxin is the same active ingredient. An FDA-approved generic digoxin is available and is substitutable at the pharmacy, which is why most people pay far less by filling the generic. The medicine was also sold historically under names such as Digitek and Digox. Because digoxin has a narrow therapeutic index, tell your prescriber if your product changes so they can confirm your dose and, if needed, recheck your level.
How much does digoxin cost without insurance?
Generic digoxin is one of the lower-cost heart medicines, but there is no single cash price. The amount you pay without insurance depends on the pharmacy, your strength and quantity, and your location, and the same prescription can cost noticeably different amounts at pharmacies within a few miles of each other. Enter your ZIP code above to compare today's digoxin cash prices across more than 60,000 pharmacies and print or show the free Rx.com coupon at the counter. The coupon is a discount program, not insurance, and prices change, so it is worth checking again at each refill.
How much does Digoxin cost without insurance?
The price of Digoxin without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Digoxin?
Common side effects of Digoxin may include: Confusion, tiredness or weakness, trouble breathing, numbness or tingling in hands, feet, or lips, Unusual behavior, stomach pain, or weight loss (in children), Fast, slow, or uneven heartbeat, Changes in vision, Nausea, vomiting, diarrhea, loss of appetite. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Digoxin?
Generic versions may be available for Digoxin. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Digoxin on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Digoxin?
The cheapest pharmacy for Digoxin depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Digoxin near you.

Digoxin Coupons & Prices

Digoxin 125MCG

Prescriptions & Refills
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Digoxin Tablet — prescription drug image
Prescription
Digoxin 125mcg (7)
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Looking for a digoxin coupon? Digoxin is the generic form of Lanoxin, a cardiac glycoside used to treat mild to moderate heart failure and to help control the heart rate in chronic atrial fibrillation. The generic tablets are already one of the lower-cost heart medicines, but the cash price still swings a surprising amount from one pharmacy counter to the next, even inside the same ZIP code. Rx.com compares cash prices at more than 60,000 pharmacies and gives you a free discount coupon you can hand to the pharmacist. Enter your ZIP above to see today's digoxin price near you.

What is digoxin and how does it work?

Digoxin is a cardiac glycoside (a digitalis glycoside). It works in two ways: it makes the heart muscle squeeze more forcefully by blocking the sodium-potassium ATPase pump, and it slows conduction through the AV node, which slows down a fast heart rate. FDA-approved uses, per the Lanoxin label, are treatment of mild to moderate heart failure in adults (where it improves exercise capacity and reduces heart-failure hospitalizations, usually added on top of standard therapy such as diuretics, ACE inhibitors or ARBs, and beta-blockers), increasing heart-muscle contractility in children with heart failure, and controlling the ventricular rate in adults with chronic atrial fibrillation.

It is important to know what digoxin does not do. It does not restore a normal heart rhythm, and it has not been shown to help people live longer. In atrial fibrillation it is generally a second-line rate-control choice behind beta-blockers and non-dihydropyridine calcium channel blockers, and it is often favored when someone also has heart failure or low blood pressure. Digoxin comes as tablets, an oral solution, and injectable and pediatric elixir forms. Because it is cleared by the kidneys, doses are lowered in kidney impairment and in older adults.

Digoxin cost without insurance, and how a coupon helps

Digoxin is available as an FDA-approved generic, and generics of long-established heart medicines are usually inexpensive compared with brand-name drugs. That said, "inexpensive" is not the same as "the same everywhere." Cash prices for the exact same strength and quantity of digoxin can differ widely between a big chain, a grocery-store pharmacy, and an independent down the street, because each pharmacy sets its own cash price. That is precisely why comparing before you fill is worth the two minutes.

There is no manufacturer savings card for generic digoxin. What there is instead: the free Rx.com discount coupon, which is a cash-price program you can use with or without insurance (it is not insurance itself). Enter your ZIP code above, pick your strength and quantity, and you will see today's price at pharmacies near you along with a coupon to show the pharmacist. If you take digoxin long term, it is also worth asking your pharmacy about a 90-day supply, and asking your prescriber whether that is appropriate for you. Prices change, so it is worth re-checking before each refill.

Digoxin vs. Lanoxin and other heart medicines

Lanoxin is the brand name; digoxin is the same active ingredient in generic form, and the generic is substitutable at the pharmacy. Unless you have a specific reason to use the brand, the generic is the usual way to keep the cost down. Digoxin was also sold historically under names such as Digitek and Digox.

Digoxin is rarely used by itself. Depending on the diagnosis, it is often taken alongside, or considered against, other heart medicines:

  • Furosemide — a loop diuretic commonly used with digoxin in heart failure to remove excess fluid. It can lower potassium, which raises the risk of digoxin toxicity, so potassium is watched.
  • Metoprolol and carvedilol — beta-blockers that are standard therapy in heart failure and are generally first-line for rate control in atrial fibrillation.
  • Diltiazem — a non-dihydropyridine calcium channel blocker also used for rate control; note that verapamil, in the same class, raises digoxin levels.
  • Amiodarone — an antiarrhythmic that, unlike digoxin, is aimed at rhythm. It also significantly raises digoxin blood levels, so the digoxin dose is usually reduced when the two are combined.

Only your prescriber can decide which of these is right for you. Never switch or stop a heart medicine on your own.

Digoxin safety: the narrow therapeutic index

Digoxin has no FDA boxed warning, but it does have a narrow therapeutic index: the helpful dose and the toxic dose are close together, so digoxin toxicity can happen even at ordinary doses. Call your prescriber if you notice nausea, vomiting, loss of appetite, diarrhea, confusion, dizziness, weakness, visual changes (blurred vision, or seeing yellow or green tints or halos around lights), or a heartbeat that is slow, fast, or irregular. Low potassium, low magnesium, and high calcium all increase the risk, which is why your doctor checks your potassium and kidney function and sometimes a serum digoxin level (in heart failure the usual target is roughly 0.5 to 0.9 ng/mL).

Digoxin should not be used by people with ventricular fibrillation or a hypersensitivity to digoxin or digitalis. It can cause severe slowing of the heart or advanced heart block in people with sinus node disease or existing AV block, and it can be dangerous in atrial fibrillation with an accessory pathway (Wolff-Parkinson-White). It is not recommended in acute heart attack or myocarditis, and it raises the risk of ventricular arrhythmias during electrical cardioversion. Many drugs interact with it, including amiodarone, verapamil, quinidine, clarithromycin, erythromycin, itraconazole, cyclosporine, propafenone, spironolactone, and potassium-lowering diuretics, so keep your full medication and supplement list current with your pharmacist. Do not stop digoxin abruptly without talking to your prescriber. This page is general information, not medical advice.

Sources & accuracy

This Digoxin information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Digoxin on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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