Famotidine
Famotidine 20MG
What is Famotidine?
Famotidine is an over-the-counter and prescription medication used to reduce stomach acid and treat conditions such as heartburn, acid reflux, gastroesophageal reflux disease (GERD), and stomach ulcers. Commonly sold under the brand name Pepcid, Famotidine helps relieve symptoms of acid-related digestive conditions and may provide long-lasting heartburn relief. Learn about Famotidine uses, dosage, side effects, and treatment options.
Side Effects
- Dark urine or pale stools, yellow eyes or skin
- Fever, chills, cough, sore throat, body aches
- Unusual bleeding, bruising, or weakness
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Call your doctor if your symptoms do not improve or if they get worse.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Some brands or forms of this medicine may contain phenylalanine (aspartame). If you have phenylketonuria (PKU), talk to your doctor before using this medicine.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or stomach cancer.
Prescription savings · · · ·
What is Famotidine ?
Famotidine is an over-the-counter and prescription medication used to reduce stomach acid and treat conditions such as heartburn, acid reflux, gastroesophageal reflux disease (GERD), and stomach ulcers. Commonly sold under the brand name Pepcid, Famotidine helps relieve symptoms of acid-related digestive conditions and may provide long-lasting heartburn relief. Learn about Famotidine uses, dosage, side effects, and treatment options.
- Dark urine or pale stools, yellow eyes or skin
- Fever, chills, cough, sore throat, body aches
- Unusual bleeding, bruising, or weakness
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Agitation, confusion, seizures
- Blistering, peeling, red skin rash
- Fast, pounding, or uneven heartbeat
- Fainting, dizziness, lightheadedness
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Call your doctor if your symptoms do not improve or if they get worse.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Some brands or forms of this medicine may contain phenylalanine (aspartame). If you have phenylketonuria (PKU), talk to your doctor before using this medicine.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or stomach cancer.
- This medicine may cause changes in your heart rhythm (including QT prolongation).
- Yellowing of your skin or the whites of your eyes.
- Unusual bleeding, bruising, or weakness.
Famotidine Coupons & Prices
Famotidine 20MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a famotidine coupon? Famotidine is the low-cost generic version of Pepcid, an H2 blocker used to treat ulcers, GERD, and heartburn. It is already an inexpensive generic, but the cash price still varies a lot from one pharmacy to the next, so comparing before you fill can make a real difference. Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies so you can find the best deal on your prescription.
What is famotidine and how does it work?
Famotidine is a histamine-2 (H2) receptor antagonist, often called an H2 blocker. It lowers the amount of acid your stomach makes, which helps ulcers heal and eases the burning of acid reflux. The prescription form is FDA-approved for active duodenal ulcers, active benign gastric ulcers, gastroesophageal reflux disease (GERD) including erosive esophagitis, and rare acid-oversupply conditions such as Zollinger-Ellison syndrome.
Famotidine is also sold over the counter as Pepcid AC and Zantac 360 to relieve and prevent heartburn and acid indigestion. It is available as a generic, which is what keeps the cost low compared with brand-name products.
Famotidine cost and coupon savings without insurance
Famotidine is one of the more affordable acid-reducing medicines because a generic is widely available. Even so, the cash price you pay can swing widely depending on which pharmacy you use, your dose, and how many tablets you fill. That is exactly why comparing prices matters, even on an inexpensive generic.
If you are paying without insurance, you do not have to accept the first price you are quoted. Enter your ZIP above to see today's famotidine price at pharmacies near you, then bring the Rx.com coupon to the counter. There is no manufacturer savings card for generic famotidine, so a pharmacy price comparison is usually the best way to keep your cost down.
Famotidine vs. other acid reducers and alternatives
Famotidine is the generic form of Pepcid. Another older H2 blocker is cimetidine. A related medicine, ranitidine (formerly Zantac), was removed from the U.S. market, and famotidine is now the common H2 blocker alternative.
For stronger or longer-lasting acid suppression, doctors may use a proton pump inhibitor (PPI) instead of an H2 blocker. Common PPIs include omeprazole, pantoprazole, and esomeprazole. Which one is right for you depends on your diagnosis, so talk with your provider before switching. Whatever you are prescribed, you can compare its price on Rx.com.
Famotidine safety and side effects
Famotidine has no boxed warning and is generally well tolerated. The most common side effects are headache, dizziness, constipation, and diarrhea. Because famotidine is cleared by the kidneys, people with moderate-to-severe kidney impairment usually need a lower dose. In older adults and those with reduced kidney function, effects on the brain such as confusion, agitation, or hallucinations can occasionally occur.
If you are using an over-the-counter famotidine product and your symptoms last longer than two weeks, stop and see a doctor. Ongoing stomach symptoms should be checked so that a more serious problem is not missed. This information is educational and is not medical advice; always follow your provider's or pharmacist's guidance for your situation.
This Famotidine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Famotidine on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Famotidine — Articles & Guides
2 articlesRelated Drugs
Browse more medications: starting with F · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.