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Famotidine

Famotidine 20MG

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What is Famotidine?

Famotidine is an over-the-counter and prescription medication used to reduce stomach acid and treat conditions such as heartburn, acid reflux, gastroesophageal reflux disease (GERD), and stomach ulcers. Commonly sold under the brand name Pepcid, Famotidine helps relieve symptoms of acid-related digestive conditions and may provide long-lasting heartburn relief. Learn about Famotidine uses, dosage, side effects, and treatment options.

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What is Famotidine ?

Famotidine is an over-the-counter and prescription medication used to reduce stomach acid and treat conditions such as heartburn, acid reflux, gastroesophageal reflux disease (GERD), and stomach ulcers. Commonly sold under the brand name Pepcid, Famotidine helps relieve symptoms of acid-related digestive conditions and may provide long-lasting heartburn relief. Learn about Famotidine uses, dosage, side effects, and treatment options.

  • Dark urine or pale stools, yellow eyes or skin
  • Fever, chills, cough, sore throat, body aches
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Agitation, confusion, seizures
  • Blistering, peeling, red skin rash
  • Fast, pounding, or uneven heartbeat
  • Fainting, dizziness, lightheadedness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Some brands or forms of this medicine may contain phenylalanine (aspartame). If you have phenylketonuria (PKU), talk to your doctor before using this medicine.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or stomach cancer.
  • This medicine may cause changes in your heart rhythm (including QT prolongation).
  • Yellowing of your skin or the whites of your eyes.
  • Unusual bleeding, bruising, or weakness.
What is famotidine used for?
Famotidine is an H2 blocker that reduces stomach acid. The prescription form is FDA-approved to treat duodenal ulcers, benign gastric ulcers, GERD (including erosive esophagitis), and rare acid-oversupply conditions like Zollinger-Ellison syndrome. Over-the-counter forms are used to relieve and prevent heartburn and acid indigestion.
Is famotidine the same as Pepcid?
Yes. Famotidine is the generic name, and Pepcid (and Pepcid AC and Zantac 360) are brand names for the same medicine. The generic and brand contain the same active ingredient, but the generic usually costs less.
How long does it take for famotidine to work?
Famotidine begins to lower stomach acid fairly quickly and is often used to relieve or prevent heartburn. For healing ulcers or treating GERD, it is taken over a longer course as directed by your doctor. Follow the timing and dose on your prescription or the package label.
Can you take famotidine every day?
Prescription famotidine is often taken daily for a set period to treat ulcers or GERD, as directed by your doctor. If you are using an over-the-counter product for heartburn and need it for more than two weeks, stop and talk with a doctor rather than continuing on your own.
What are the side effects of famotidine?
The most common side effects are headache, dizziness, constipation, and diarrhea. In older adults and people with kidney problems, confusion, agitation, or hallucinations can occasionally occur, and a lower dose may be needed. Contact your provider if side effects concern you.
How much does Famotidine cost without insurance?
The price of Famotidine without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Famotidine?
Common side effects of Famotidine may include: Dark urine or pale stools, yellow eyes or skin, Fever, chills, cough, sore throat, body aches, Unusual bleeding, bruising, or weakness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Agitation, confusion, seizures. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Famotidine?
Generic versions may be available for Famotidine. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Famotidine 20MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Famotidine 20MG?
The cheapest pharmacy for Famotidine 20MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Famotidine 20MG near you.

Famotidine Coupons & Prices

Famotidine 20MG

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Famotidine 20mg (14)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a famotidine coupon? Famotidine is the low-cost generic version of Pepcid, an H2 blocker used to treat ulcers, GERD, and heartburn. It is already an inexpensive generic, but the cash price still varies a lot from one pharmacy to the next, so comparing before you fill can make a real difference. Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies so you can find the best deal on your prescription.

What is famotidine and how does it work?

Famotidine is a histamine-2 (H2) receptor antagonist, often called an H2 blocker. It lowers the amount of acid your stomach makes, which helps ulcers heal and eases the burning of acid reflux. The prescription form is FDA-approved for active duodenal ulcers, active benign gastric ulcers, gastroesophageal reflux disease (GERD) including erosive esophagitis, and rare acid-oversupply conditions such as Zollinger-Ellison syndrome.

Famotidine is also sold over the counter as Pepcid AC and Zantac 360 to relieve and prevent heartburn and acid indigestion. It is available as a generic, which is what keeps the cost low compared with brand-name products.

Famotidine cost and coupon savings without insurance

Famotidine is one of the more affordable acid-reducing medicines because a generic is widely available. Even so, the cash price you pay can swing widely depending on which pharmacy you use, your dose, and how many tablets you fill. That is exactly why comparing prices matters, even on an inexpensive generic.

If you are paying without insurance, you do not have to accept the first price you are quoted. Enter your ZIP above to see today's famotidine price at pharmacies near you, then bring the Rx.com coupon to the counter. There is no manufacturer savings card for generic famotidine, so a pharmacy price comparison is usually the best way to keep your cost down.

Famotidine vs. other acid reducers and alternatives

Famotidine is the generic form of Pepcid. Another older H2 blocker is cimetidine. A related medicine, ranitidine (formerly Zantac), was removed from the U.S. market, and famotidine is now the common H2 blocker alternative.

For stronger or longer-lasting acid suppression, doctors may use a proton pump inhibitor (PPI) instead of an H2 blocker. Common PPIs include omeprazole, pantoprazole, and esomeprazole. Which one is right for you depends on your diagnosis, so talk with your provider before switching. Whatever you are prescribed, you can compare its price on Rx.com.

Famotidine safety and side effects

Famotidine has no boxed warning and is generally well tolerated. The most common side effects are headache, dizziness, constipation, and diarrhea. Because famotidine is cleared by the kidneys, people with moderate-to-severe kidney impairment usually need a lower dose. In older adults and those with reduced kidney function, effects on the brain such as confusion, agitation, or hallucinations can occasionally occur.

If you are using an over-the-counter famotidine product and your symptoms last longer than two weeks, stop and see a doctor. Ongoing stomach symptoms should be checked so that a more serious problem is not missed. This information is educational and is not medical advice; always follow your provider's or pharmacist's guidance for your situation.

Sources & accuracy

This Famotidine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Famotidine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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