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Histex Pd Bottle — prescription drug image

Histex Pd

Histex PD 30ML of 1.25MG/ML

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What is Histex Pd?

Histex PD is an oral antihistamine medication used primarily for the treatment of symptoms associated with allergies, such as sneezing, runny nose, and itchy eyes. It contains the active ingredient phenylephrine hydrochloride, which serves as a decongestant to relieve nasal congestion. Histex PD is suitable for adults and children, providing effective relief from allergy symptoms and common cold.

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What is Histex Pd ?

Histex PD is an oral antihistamine medication used primarily for the treatment of symptoms associated with allergies, such as sneezing, runny nose, and itchy eyes. It contains the active ingredient phenylephrine hydrochloride, which serves as a decongestant to relieve nasal congestion. Histex PD is suitable for adults and children, providing effective relief from allergy symptoms and common cold.
  • Severe drowsiness, clumsiness, or confusion
  • Faintness
  • Fast heartbeat
  • Shortness of breath or trouble breathing
  • Nervousness
  • Changes in vision, such as trouble focusing
  • This medicine may cause drowsiness. If it does, avoid driving a car or using machinery.
  • This medicine may cause a skin rash when you are out in the sun. Use a sunscreen when you are outside, and try not to spend long periods in direct sunlight.
  • Ask your doctor before taking this medicine if you are pregnant or breastfeeding, or if you have glaucoma or trouble urinating.
  • This medicine might contain phenylalanine. This is only a concern if you have a disorder called phenylketonuria (a problem with amino acids). Talk to your doctor before using this medicine.
  • Side effects of this medicine may occur more frequently in young children and older adults.
  • Some antihistamine syrups contain alcohol.
What is Histex PD used for?
Histex PD is an over-the-counter antihistamine drop used for the temporary relief of a runny nose, sneezing, and itchy, watery eyes caused by hay fever (allergic rhinitis) or other upper respiratory allergies. It comes in a pediatric drop formulation with dropperful dosing, and the label also includes separate dosing for adults.
Is Histex PD the same as Benadryl?
No. Benadryl's active ingredient is diphenhydramine, while Histex PD's active ingredient is triprolidine hydrochloride. Both are older, first-generation antihistamines that can cause drowsiness, but they are different active ingredients in different chemical classes, so they aren't interchangeable milligram for milligram.
What age can children take Histex PD drops?
According to the Drug Facts label, children under 6 years old should only use Histex PD after checking with a doctor. Children 6 years and older have specific dosing directions printed on the label, and there is a separate dosing line for older children and adults.
How much Histex PD can I give my child?
The exact amount and how often to give it depend on your child's age and are printed on the product's Drug Facts label — follow those directions exactly and don't exceed the maximum listed. For children under 6, don't give any dose without first talking to a doctor. If you're ever unsure, call your pharmacist or your child's doctor before dosing.
Is triprolidine safe for infants and toddlers?
The Histex PD label directs caregivers to consult a doctor before giving it to any child under 6 years old, which includes infants and toddlers. Don't use it simply to make a baby or toddler sleepy — sedating antihistamines like this one should only be given for allergy symptoms as directed, not as a sleep aid. Talk to your child's pediatrician before using any antihistamine in an infant or toddler.
How much does Histex Pd cost without insurance?
The price of Histex Pd without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Histex Pd?
Common side effects of Histex Pd may include: Severe drowsiness, clumsiness, or confusion, Faintness, Fast heartbeat, Shortness of breath or trouble breathing, Nervousness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Histex Pd?
Generic versions may be available for Histex Pd. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Histex Pd on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Histex Pd?
The cheapest pharmacy for Histex Pd depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Histex Pd near you.

Histex Pd Coupons & Prices

Histex PD 30ML of 1.25MG/ML

Prescriptions & Refills
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Histex Pd Bottle — prescription drug image
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Histex PD (triprolidine hydrochloride) is an over-the-counter antihistamine drop used for temporary relief of a runny nose, sneezing, and itchy, watery eyes caused by hay fever or other upper respiratory allergies; because it doesn't require a prescription, the best way to find a low price is to search for a histex-pd coupon on Rx.com and enter your ZIP code to compare pharmacy prices near you before you buy.

What Is Histex PD?

Histex PD is the brand name for triprolidine hydrochloride, a first-generation (sedating) antihistamine in the alkylamine class. It's sold under several OTC brand names, including Histex PD (Drops), Histex PDX, PD-Hist D Drops, and Vanahist PD, and it's regulated under an FDA over-the-counter monograph rather than as an FDA-approved prescription drug. The drop formulation uses dropperful dosing and is intended for temporary relief of a runny nose, sneezing, and itchy or watery eyes caused by hay fever (allergic rhinitis) or other upper respiratory allergies.

Comparing Prices and Coupons for Histex PD

Because Histex PD is available without a prescription, you can buy it directly at the pharmacy counter — but that doesn't mean every pharmacy charges the same price. A generic version of triprolidine hydrochloride drops is available, and prices for both the brand and the generic can vary from one pharmacy to the next. Enter your ZIP code above to compare prices at pharmacies near you; in some cases an OTC product like this one ends up cheaper with a coupon, or when a doctor writes it as a prescription, than it does off the shelf.

Histex PD doesn't have a manufacturer savings card program, so a pharmacy discount card or coupon is the main lever for lowering your out-of-pocket cost on this product.

Histex PD vs. Other Antihistamines

Histex PD is not the same medicine as Benadryl. Benadryl's active ingredient is diphenhydramine, a different first-generation antihistamine chemical class, while Histex PD contains triprolidine, which belongs to the alkylamine class along with chlorpheniramine and brompheniramine — all three are older, sedating antihistamines that have been used for decades to treat seasonal allergy symptoms. Diphenhydramine is also a first-generation sedating antihistamine, but it's a different chemical class than triprolidine.

If daytime drowsiness is a concern, newer second-generation antihistamines such as cetirizine and loratadine are formulated to be non-drowsy for most people and are taken once daily. Talk to your pharmacist or doctor about which option fits your or your child's age and symptoms best.

Safety Information

Ask a doctor before use if your child has a breathing problem such as emphysema or chronic bronchitis, has glaucoma, or is taking sedatives or tranquilizers, since those can increase the drowsiness effect. First-generation antihistamines like triprolidine can cause excitability (especially in children) or drowsiness in others, so avoid alcohol or other central-nervous-system depressants and use caution with driving or other hazardous activities if you feel drowsy. As with any medicine that can cause drowsiness, Histex PD should be used only as directed for allergy symptoms, not as a way to help a child fall asleep — talk to your doctor about the best way to manage nighttime symptoms. Other possible effects include dry mouth and urinary retention, which are common with this class of antihistamine.

Never exceed the dose on the Drug Facts label, and keep the product out of reach of children — an antihistamine overdose in a young child can be serious, and you should contact Poison Control right away if you suspect one. This information isn't a substitute for medical advice; talk to your doctor or pharmacist about whether Histex PD is right for you or your child.

Sources & accuracy

This Histex Pd information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Histex Pd on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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