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Hurricaine One

HurriCaine One 2 Solution

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What is Hurricaine One?

Hurricaine One is a topical anesthetic primarily used for oral mucosal pain relief. Containing 20% benzocaine, it provides rapid-onset, localized numbing to alleviate discomfort from dental procedures, minor mouth irritations, or sore throats.

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What is Hurricaine One ?

Hurricaine One is a topical anesthetic primarily used for oral mucosal pain relief. Containing 20% benzocaine, it provides rapid-onset, localized numbing to alleviate discomfort from dental procedures, minor mouth irritations, or sore throats.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Confusion, headache, lightheadedness, fast heartbeat or breathing
  • Fever, swelling, or rash
  • Unusual drowsiness
  • Pale, gray, or blue skin, lips, or nails
  • Increased pain, irritation, or redness
  • Tell your doctor if you are pregnant or breastfeeding, or if you have lung or breathing problems (including asthma, bronchitis, or emphysema), heart disease, or G6PD deficiency. Tell your doctor if you smoke.
  • Do not give this medicine to a child younger than 2 years of age. This medicine should not be used for teething pain.
  • This medicine may cause a rare but serious blood problem called methemoglobinemia. This condition may occur after use of the spray for medical procedures or use of the over-the-counter gel or liquid for mouth sores or teething in children.
  • The liquid form of this medicine is flammable. Keep it away from heat or an open flame. Do not smoke while you are using this medicine.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
How fast does Hurricaine One work?
Hurricaine One's 20% benzocaine typically begins numbing the treated tissue within about 15 to 30 seconds of application.
Is Hurricaine One safe for children?
The FDA advises that benzocaine oral products should not be used in infants or children under 2 years old due to a risk of methemoglobinemia. Use in older children and adults should follow product directions or a provider's guidance.
Is Hurricaine One available without a prescription?
Hurricaine products are regulated as OTC monograph drugs, but Hurricaine One's single-dose applicator format is mainly distributed to dental and medical offices rather than sold directly on pharmacy shelves.
How long does the numbing from Hurricaine One last?
Topical benzocaine anesthesia is generally short-acting, lasting roughly 15 minutes, which is why it's often used just before an injection or a brief procedure.
How much does Hurricaine One cost without insurance?
The price of Hurricaine One without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 46% off retail prices with a free Rx.com coupon.
What are the common side effects of Hurricaine One?
Common side effects of Hurricaine One may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Confusion, headache, lightheadedness, fast heartbeat or breathing, Fever, swelling, or rash, Unusual drowsiness, Pale, gray, or blue skin, lips, or nails. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Hurricaine One?
Generic versions may be available for Hurricaine One. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Hurricaine One on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Hurricaine One?
The cheapest pharmacy for Hurricaine One depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Hurricaine One near you.

Hurricaine One Coupons & Prices

HurriCaine One 2 Solution

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Hurricaine One Box — prescription drug image
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Hurricaine One prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
20%, 0.5ml, two unit dose oral sprays · Box 2 $337.99 $27.05
20%, 0.5ml, 25 unit dose oral sprays · Box 25 $410.25 $168.55

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Hurricaine One is a single-use, unit-dose oral anesthetic spray containing 20% benzocaine, used to temporarily numb mouth and gum tissue before dental work or to relieve minor mouth irritation. It's typically dispensed by dental offices rather than sold on a pharmacy shelf, so it's worth checking a Hurricaine coupon if you're paying out of pocket.

What Is Hurricaine One and How Does It Work?

Hurricaine One delivers a metered 0.5 mL dose of 20% benzocaine, a local anesthetic, from a single-use applicator. Benzocaine works by temporarily blocking nerve signals in the area where it's applied, numbing the tissue within roughly 15 to 30 seconds. The unit-dose format is designed to reduce cross-contamination between patients compared with multi-use bottles or gels.

Where Hurricaine One Is Used and How to Save

Hurricaine One is most often used in dental and medical offices before injections, minor dental procedures, or scoping procedures, and for temporary relief of minor mouth or gum irritation, denture or orthodontic-appliance discomfort, and canker sores. Because it's a benzocaine product, prices can vary by pharmacy or supplier. Enter your ZIP above to compare pricing before you buy.

Hurricaine One vs. Other Topical Anesthetics

Hurricaine's benzocaine formulation is one of several topical oral anesthetics used in dental settings; others include lidocaine-based topical gels and sprays. Benzocaine products like Hurricaine tend to have a faster onset but a shorter duration of numbing than lidocaine. Which product a provider chooses often depends on the procedure and how long numbing is needed.

Safety Information

  • The FDA warns that benzocaine oral products should never be used in infants or children younger than 2 years, including for teething, because of a rare but serious risk of methemoglobinemia, a condition that reduces the blood's oxygen-carrying capacity.
  • Seek medical attention right away if you or a child develops pale, gray, or blue-colored skin, lips, or nail beds; shortness of breath; fatigue; or rapid heart rate after using a benzocaine product.
  • This is not medical advice — follow your dentist's or doctor's directions for use, and tell your provider about any known sensitivity to local anesthetics before this product is used.
Sources & accuracy

This Hurricaine One information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Hurricaine One on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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