What is Isosorb Dinitrate-Hydralazine ?

Isosorbide dinitrate-hydralazine is a combination medication used primarily in the management of heart failure, particularly in self-identified African American patients, to improve survival and reduce the rate of hospitalization. Isosorbide dinitrate works by dilating blood vessels and reducing the workload on the heart, while hydralazine acts as a vasodilator, relaxing blood vessels to decrease blood pressure and improve blood flow. This synergistic effect enhances cardiac output and alleviates symptoms of heart failure.

• Numbness, tingling, or burning pain in your hands, arms, legs, or feet
• Lightheadedness, fainting
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain, fast or pounding heartbeat
• Joint pain, rash, fever

• Tell your doctor if you are pregnant or breastfeeding, or if you have low blood pressure or heart disease.
• This medicine may cause the following problems: Symptoms of lupus (may go away when you stop using the medicine)Worsening heart disease
• This medicine may make you dizzy or lightheaded. This is more likely to happen if you are dehydrated. Drink plenty of fluids to help prevent dehydration. Stand up slowly to help prevent dizziness. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. These symptoms may be worse if you drink alcohol.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.