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Isosorbide Mononitrate Er Tablet — prescription drug image

Isosorbide Mononitrate Er

Isosorbide Mononitrate ER 30MG

What is Isosorbide Mononitrate Er?

Isosorbide Mononitrate Er is a generic drug that is used to prevent a certain type of chest pain (angina). The average Isosorbide Mononitrate Er price is about $19 for a supply of 30, 30 mg tablets,extended release. You can use our Rx.com savings offer to get an average of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Isosorbide Mononitrate Er ?

Isosorbide Mononitrate Er is a generic drug that is used to prevent a certain type of chest pain (angina). The average Isosorbide Mononitrate Er price is about $19 for a supply of 30, 30 mg tablets,extended release. You can use our Rx.com savings offer to get an average of up to 80% off of the retail price at participating pharmacies near you.
  • Severe or ongoing dizziness, lightheadedness, or fainting
  • Slow heartbeat, increased chest pain
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Severe headache
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell your doctor if you are pregnant or breastfeeding. Tell him if you had a recent heart attack or you have heart failure, an enlarged heart, low blood pressure, or other heart problems.
  • This medicine may cause the following problems:Severe low blood pressureWorsening of chest pain caused by an enlarged heart
  • Medicines that treat chest pain sometimes cause headaches. These headaches are a sign that the medicine is working. Do not stop taking the medicine or change the time you take it in order to avoid the headaches. Ask your doctor if you can take aspirin or acetaminophen to treat the headache.
  • This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. You may feel lightheaded when standing, so stand up slowly. Drinking alcohol may make these symptoms worse.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
What is isosorbide mononitrate ER used for?
It is FDA-approved to prevent angina (chest pain) caused by coronary artery disease when taken regularly on an ongoing schedule. It is not used to stop an angina attack once it has started.
Is isosorbide mononitrate the same as isosorbide dinitrate?
No. They are related nitrate medications but are different drugs, with different dosing schedules and, in some cases, different forms. Your doctor prescribes the one that fits your specific treatment plan.
Why can't you take Viagra with isosorbide mononitrate?
Combining a nitrate like isosorbide mononitrate with a PDE5 inhibitor such as sildenafil (Viagra), tadalafil, or vardenafil can cause a severe and potentially life-threatening drop in blood pressure. This combination should always be avoided.
What time of day should you take isosorbide mononitrate ER?
Your doctor will set a specific schedule for you, since nitrate dosing is timed to include a nitrate-free interval that helps prevent your body from building tolerance to the medication. Follow your prescribed schedule exactly and ask your doctor or pharmacist if you are unsure.
What are the side effects of isosorbide mononitrate extended-release?
The most common side effects are headache, dizziness or lightheadedness (especially when standing up or drinking alcohol), and flushing. Headache can be significant for some patients and may be managed with a dose adjustment from your doctor. Tablets should be swallowed whole, not crushed, chewed, or split.
How much does Isosorbide Mononitrate Er cost without insurance?
The price of Isosorbide Mononitrate Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 53% off retail prices with a free Rx.com coupon.
What are the common side effects of Isosorbide Mononitrate Er?
Common side effects of Isosorbide Mononitrate Er may include: Severe or ongoing dizziness, lightheadedness, or fainting, Slow heartbeat, increased chest pain, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Severe headache. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Isosorbide Mononitrate Er?
Generic versions may be available for Isosorbide Mononitrate Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Isosorbide Mononitrate Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Isosorbide Mononitrate Er?
The cheapest pharmacy for Isosorbide Mononitrate Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Isosorbide Mononitrate Er near you.

Isosorbide Mononitrate Er Coupons & Prices

Isosorbide Mononitrate ER 30MG

Isosorbide Mononitrate Er Tablet — prescription drug image
Prescription
Isosorbide Mononitrate Er 30mg (15)
your area ·

Looking for an isosorbide mononitrate ER coupon? This extended-release nitrate is a generic medication, but the cash price for the same tablet still varies a surprising amount from one pharmacy to the next, so it pays to compare before you fill. Rx.com checks pricing across 60,000+ U.S. pharmacies so you can enter your ZIP above and see today's price near you.

What is isosorbide mononitrate ER and how does it work?

Isosorbide mononitrate extended-release is a nitrate vasodilator taken on a regular, ongoing schedule to help prevent angina (chest pain) caused by coronary artery disease. It works by relaxing and widening blood vessels, which reduces the heart's workload and helps prevent the chest pain that comes with reduced blood flow to the heart muscle.

It is important to understand what this medicine is not for: it is not used to stop an angina attack that is already happening, because it does not act fast enough for that. Sublingual (under-the-tongue) nitroglycerin is the medication used to treat an acute attack. The brand name Imdur has been discontinued in the U.S., but the extended-release generic tablet is widely available. Immediate-release isosorbide mononitrate was previously sold under the brand names Monoket and Ismo, both since discontinued in the U.S., and is a different product from the ER tablet this page covers.

Isosorbide mononitrate ER cost and coupon savings

Isosorbide mononitrate ER is available as a generic, so there is no brand-name version currently on the market to compare it against. That does not mean every pharmacy charges the same amount, however. Cash prices for generic medications can differ significantly between pharmacies in the same city, so comparing before you fill your prescription is worth the extra minute.

Enter your ZIP code above to see today's price at pharmacies near you, along with any available coupon. Prices can also change over time, so it is worth checking again at refill time rather than assuming last month's price still applies.

How isosorbide mononitrate ER compares to other options

Isosorbide mononitrate ER is one of several long-acting nitrates used for ongoing angina prevention. Isosorbide dinitrate is a related nitrate that some patients take instead, typically on a more frequent dosing schedule. Nitroglycerin is a different form of nitrate used specifically to treat an acute angina attack as it starts, rather than to prevent one.

Because angina often occurs alongside other cardiovascular conditions, some patients are also prescribed a blood pressure medication such as amlodipine or a beta blocker such as metoprolol succinate ER. These work through different mechanisms and are commonly used together with a nitrate as part of a broader treatment plan set by your provider.

Safety information

Isosorbide mononitrate ER must never be combined with PDE5 inhibitor medications such as sildenafil, tadalafil, or vardenafil, or with the medication riociguat. Taking any of these together can cause a severe, life-threatening drop in blood pressure. Tell every provider and pharmacist about all medications you take, and never start a PDE5 inhibitor while on this nitrate without talking to your doctor first.

This medicine should also be avoided by people with a known hypersensitivity to nitrates. Common side effects include headache (which can be significant and may improve with continued use or a dose adjustment), dizziness or lightheadedness from low blood pressure (use extra caution with alcohol or when standing up quickly), and flushing. The extended-release tablet must be swallowed whole and should not be crushed, chewed, or split. This is general information, not medical advice — talk with your doctor or pharmacist about what applies to you.

Sources & accuracy

This Isosorbide Mononitrate Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Isosorbide Mononitrate Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.