Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Loratadine-D 24Hr Box — prescription drug image

Loratadine-D 24Hr

Loratadine-D 24HR 10 Tablets Extended Release 24 Hour

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Loratadine-D 24Hr?

Loratadine-D 24 Hour is an over-the-counter antihistamine and decongestant combination used for the relief of allergy symptoms such as nasal congestion, sneezing, and runny nose. It contains loratadine, a long-acting antihistamine, and pseudoephedrine, a decongestant that alleviates nasal congestion, providing up to 24 hours of symptom relief.

Prescription savings · · · ·

What is Loratadine-D 24Hr ?

Loratadine-D 24 Hour is an over-the-counter antihistamine and decongestant combination used for the relief of allergy symptoms such as nasal congestion, sneezing, and runny nose. It contains loratadine, a long-acting antihistamine, and pseudoephedrine, a decongestant that alleviates nasal congestion, providing up to 24 hours of symptom relief.
  • Dizziness or drowsiness
  • Fainting or passing out
  • Dry mouth or nose
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, pounding, or irregular heartbeat
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, high blood pressure, diabetes, thyroid problems, or trouble urinating.
  • This medicine may make you drowsy or dizzy. Be careful if you are driving or using machinery.
What is loratadine-D 24 hour used for?
It's an OTC combination used for temporary relief of nasal and sinus congestion, sneezing, runny nose, and itchy or watery eyes and itchy nose or throat caused by hay fever (allergic rhinitis) or the common cold. Loratadine treats the allergy symptoms and pseudoephedrine treats the congestion.
Is loratadine-D 24 hour the same as Claritin-D?
Claritin-D 24 Hour is the original brand name for this exact combination (loratadine 10 mg / pseudoephedrine sulfate 240 mg extended-release). Loratadine-D 24 Hour is the generic version, along with other brands like Allergy Relief-D and various store brands, all containing the same active ingredients.
Can I buy loratadine-D 24 hour without ID or is it behind the pharmacy counter?
You will need to show ID. Even though this product doesn't require a prescription, it's sold from behind the pharmacy counter under the federal Combat Methamphetamine Epidemic Act because it contains pseudoephedrine, and purchase quantities are limited.
What is the difference between loratadine-D 12 hour and 24 hour?
Both combine loratadine with pseudoephedrine, but the 24-hour version is an extended-release tablet taken once daily, while the 12-hour version is taken twice daily. Talk to a pharmacist if you're unsure which dosing schedule fits your routine.
Is pseudoephedrine sulfate a controlled substance?
No. Pseudoephedrine is not a DEA-scheduled controlled substance. It is regulated separately under the federal Combat Methamphetamine Epidemic Act, which requires photo ID and limits how much you can purchase, but it does not require a prescription.
Can I take loratadine-D 24 hour with high blood pressure?
Ask a doctor before using it if you have high blood pressure. The pseudoephedrine in this product can raise blood pressure and heart rate, so people with hypertension, heart disease, thyroid disease, diabetes, glaucoma, or prostate-related urinary difficulty should check with a healthcare provider first.
How much does Loratadine-D 24Hr cost without insurance?
The price of Loratadine-D 24Hr without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 58% off retail prices with a free Rx.com coupon.
What are the common side effects of Loratadine-D 24Hr?
Common side effects of Loratadine-D 24Hr may include: Dizziness or drowsiness, Fainting or passing out, Dry mouth or nose, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Fast, pounding, or irregular heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Loratadine-D 24Hr?
Generic versions may be available for Loratadine-D 24Hr. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Loratadine-D 24Hr on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Loratadine-D 24Hr?
The cheapest pharmacy for Loratadine-D 24Hr depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Loratadine-D 24Hr near you.

Loratadine-D 24Hr Coupons & Prices

Loratadine-D 24HR 10 Tablets Extended Release 24 Hour

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Loratadine-D 24Hr Box — prescription drug image
Prescription
Loratadine-D 24Hr 10 tablets extended release 24 hour (1)
your area ·
QUAD by MEDVi · 4-in-1 ED treatment

4 ED medications in one dose

Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours

$114/mo Consult, meds & shipping included 4-in-1 formula
See QUAD by MEDVi Free online visit · No commitment
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.

Loratadine-D 24 Hour (generic name loratadine 10 mg / pseudoephedrine sulfate 240 mg extended-release) is an over-the-counter antihistamine-decongestant combination sold under names like Claritin-D 24 Hour, Allergy Relief-D, and various store brands; it's available without a prescription, but if you're comparing what you'll pay, a loratadine-d-24hr coupon can still help since pharmacy prices for this product vary — enter your ZIP above to see today's price at pharmacies near you.

What Is Loratadine-D 24 Hour and How Does It Work?

Loratadine-D 24 Hour combines two active ingredients in one once-daily tablet: loratadine, a non-drowsy antihistamine, and pseudoephedrine sulfate, a decongestant, in an extended-release core. Under the FDA's OTC monograph, it's used for temporary relief of nasal and sinus congestion, sneezing, runny nose, and itchy/watery eyes or itchy nose and throat caused by hay fever (allergic rhinitis) or the common cold.

The tablet is designed to release the decongestant slowly over 24 hours, so it should be swallowed whole. Do not crush, chew, or split it, since breaking the extended-release core can release the full dose at once.

Comparing Prices and Saving on Loratadine-D 24 Hour

Because this is a generic OTC combination, it's sold under several store and brand names, and prices can differ from one pharmacy to the next. There's no manufacturer copay card for this product, but a pharmacy coupon can sometimes bring the price at the register below the shelf price, or below what you'd otherwise pay out of pocket. Enter your ZIP code above to compare current prices at pharmacies near you before you buy.

Keep in mind this product is sold "behind the counter" at pharmacies under the federal Combat Methamphetamine Epidemic Act, so you'll need to show ID and purchases are limited in quantity, even though a prescription isn't required.

Loratadine-D 24 Hour vs. Other Allergy Options

If you don't need the decongestant, plain loratadine covers the antihistamine allergy symptoms on its own. If you need a shorter-acting decongestant combination, loratadine-D 12 Hour is dosed twice daily instead of once. Some people prefer taking the decongestant, pseudoephedrine, separately from the antihistamine so they can adjust each one independently.

Other non-drowsy antihistamines, such as cetirizine and fexofenadine, are also available OTC and are sometimes combined with pseudoephedrine in similar 24-hour products. The brand-name version, Claritin, is the antihistamine-only equivalent without the decongestant.

Safety Information

Loratadine-D 24 Hour does not carry an FDA boxed warning. However, you should not use it with, or within two weeks of, a monoamine oxidase inhibitor (MAOI). Ask a doctor before use if you have heart disease, high blood pressure, thyroid disease, diabetes, glaucoma, or trouble urinating due to an enlarged prostate, since the pseudoephedrine component can raise blood pressure and heart rate and cause insomnia, nervousness, or dizziness. It is not intended for children under 12.

This information is general and not a substitute for medical advice — talk to your doctor or pharmacist about whether this product is appropriate for you.

Sources & accuracy

This Loratadine-D 24Hr information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Loratadine-D 24Hr on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Related Drugs

Browse more medications: starting with L · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!