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Memantine Hcl Er Capsule Extended Release 24 Hour — prescription drug image

Memantine Hcl Er

Memantine HCl ER 28MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Memantine Hcl Er?

Namenda XR is used to treat dementia caused by Alzheimer’s. There is not a Namenda XR generic drug currently available on the market. On average Namenda XR is priced at about $492 for a supply of 30, 28 mg extended-release capsules. Luckily, you can use our Rx.com savings offer to receive a Namenda XR discount of up to 80% off the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Memantine Hcl Er ?

Namenda XR is used to treat dementia caused by Alzheimer’s. There is not a Namenda XR generic drug currently available on the market. On average Namenda XR is priced at about $492 for a supply of 30, 28 mg extended-release capsules. Luckily, you can use our Rx.com savings offer to receive a Namenda XR discount of up to 80% off the retail price at participating pharmacies near you.
  • Sudden or severe headache.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate.
  • Chest pain.
  • Lightheadedness, dizziness, or fainting.
  • Seeing or hearing things that are not there.
  • Severe sleepiness, restlessness, or confusion.
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bladder problems or difficulty with urination, or epilepsy or seizures.
  • Check with your doctor right away if you get a urinary tract infection. This includes any infection in your bladder or kidneys. Your dose of this medicine might need to be changed while you have an infection.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Lightheadedness, dizziness, or fainting.
  • Seeing or hearing things that are not there.
  • Severe sleepiness, restlessness, or confusion.
  • Sudden or severe headache.
Is Namenda XR still available?
No, the brand-name Namenda XR has been discontinued in the US. Memantine HCl extended-release capsules are available as a generic from multiple manufacturers, which is what pharmacies now dispense for this prescription.
What is memantine HCl ER used for?
It's approved for moderate to severe dementia of the Alzheimer's type. It doesn't cure or reverse Alzheimer's disease, but it may help slow decline in daily functioning for some patients.
What are the most common side effects?
The most commonly reported side effects in clinical trials were headache, dizziness, and diarrhea.
Do I need a lower dose if I have kidney problems?
Patients with severe renal impairment are typically started on a lower target dose, so make sure your doctor knows about any kidney disease before you start this medication.
How much does Memantine Hcl Er cost without insurance?
The price of Memantine Hcl Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 43% off retail prices with a free Rx.com coupon.
What are the common side effects of Memantine Hcl Er?
Common side effects of Memantine Hcl Er may include: Sudden or severe headache., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Change in how much or how often you urinate., Chest pain., Lightheadedness, dizziness, or fainting.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Memantine Hcl Er?
Generic versions may be available for Memantine Hcl Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Memantine Hcl Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Memantine Hcl Er?
The cheapest pharmacy for Memantine Hcl Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Memantine Hcl Er near you.

Memantine Hcl Er Coupons & Prices

Memantine HCl ER 28MG

Prescriptions & Refills
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Memantine Hcl Er Capsule Extended Release 24 Hour — prescription drug image
Prescription
Memantine Hcl Er 28mg (7)
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Memantine Hcl Er prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
7mg · Capsule Extended Release 24 Hour 30 $458.40 $23.12
14mg · Capsule Extended Release 24 Hour 30 $97.81 $23.29
21mg · Capsule Extended Release 24 Hour 30 $389.99 $22.62
28mg · Capsule Extended Release 24 Hour 30 $458.49 $25.82

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Memantine HCl ER (extended-release) capsules are the once-daily generic version of what used to be sold as the brand Namenda XR, and "memantine-hcl-er coupon" is how many people search for it. Prices for this generic can vary by pharmacy, so it's worth comparing before you fill it. Enter your ZIP above to see today's price near you.

What is memantine HCl ER and how does it work?

Memantine is an NMDA-receptor antagonist indicated for moderate to severe dementia of the Alzheimer's type. The extended-release capsule is taken once daily and works by moderating the activity of glutamate, a brain chemical that can overstimulate nerve cells when present in excess in Alzheimer's disease; the goal is to help slow the decline in day-to-day functioning, not to reverse or cure the disease.

The brand-name Namenda XR is no longer marketed in the US; memantine HCl extended-release capsules are available only as a generic from multiple manufacturers today.

Comparing generic pricing

Because Namenda XR is no longer sold as a brand, essentially everyone filling this prescription today is getting the generic. Even so, cash prices for the same generic capsule can differ a fair amount between pharmacies. Rx.com compares pricing across 60,000+ pharmacies so you can find the lower-cost option near you, which matters for a medication many patients take long-term.

  • Ask your pharmacy about 90-day fills, which can lower the per-dose cost for a maintenance medication like this
  • Compare cash pricing even with insurance, since some plans' copays are higher than the cash price

Alternatives and related dementia medications

Memantine is sometimes combined with a cholinesterase inhibitor such as donepezil for Alzheimer's disease, and immediate-release memantine tablets are another dosing option some doctors prefer. Any change to an Alzheimer's medication regimen should be made with the prescribing doctor, since abrupt changes can affect symptom control.

Safety information

The most common side effects reported with memantine HCl ER include headache, dizziness, and diarrhea. Patients with severe kidney impairment typically need a lower target dose, so tell your doctor about any kidney problems. As with any medication for a person with cognitive impairment, caregivers should watch for new or worsening confusion, and contact the prescribing doctor with questions about dosing changes. This is general information, not medical advice — talk to your provider about your specific situation.

Sources & accuracy

This Memantine Hcl Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Memantine Hcl Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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