Naphcon-A
Naphcon-A 15ML of 0.025-0.3%
What is Naphcon-A?
Naphcon-A is an over-the-counter eye drop medication used primarily for the temporary relief of redness and itching of the eye due to allergies. It contains a combination of naphazoline, a decongestant that reduces redness, and pheniramine, an antihistamine that alleviates itching. Users should consult their healthcare provider before use, especially if they have any pre-existing eye conditions.Side Effects
- Fast or irregular heartbeat
- Severe headache
- Eye pain, changes in vision
Warnings
- Check with your doctor if you have eye discomfort you did not have before using this medicine.
- If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
- Check with your doctor before using this medicine if you have high blood pressure, diabetes, or any heart problems.
- Use these drops exactly as your doctor ordered. Using more of them or using them for a longer time may cause serious side effects.
Prescription savings · · · ·
What is Naphcon-A ?
Naphcon-A is an over-the-counter eye drop medication used primarily for the temporary relief of redness and itching of the eye due to allergies. It contains a combination of naphazoline, a decongestant that reduces redness, and pheniramine, an antihistamine that alleviates itching. Users should consult their healthcare provider before use, especially if they have any pre-existing eye conditions.- Fast or irregular heartbeat
- Severe headache
- Eye pain, changes in vision
- Check with your doctor if you have eye discomfort you did not have before using this medicine.
- If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
- Check with your doctor before using this medicine if you have high blood pressure, diabetes, or any heart problems.
- Use these drops exactly as your doctor ordered. Using more of them or using them for a longer time may cause serious side effects.
Naphcon-A Coupons & Prices
Naphcon-A 15ML of 0.025-0.3%
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Naphcon-A prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 15ml of 0.025-0.3% · Bottle | 15 | $14.49 | $11.06 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Naphcon-A (naphazoline hydrochloride 0.025% / pheniramine maleate 0.3%) is an over-the-counter eye drop that temporarily relieves redness and itching from seasonal allergens like ragweed, pollen, grass, and pet dander, and it's sold without a prescription at most pharmacies, so before you buy, enter your ZIP above to see today's price and check whether an Rx.com coupon brings the cost down at your pharmacy.
What Is Naphcon-A and How Does It Work?
Naphcon-A is a combination antihistamine and decongestant (vasoconstrictor) eye drop made by Alcon. The pheniramine maleate is an antihistamine that calms the itching caused by an allergic reaction, while the naphazoline hydrochloride narrows blood vessels in the eye to reduce redness. The same combination of ingredients is also sold under other brand names, including Opcon-A and Visine Allergy Eye Relief Multi-Action.
Naphcon-A is intended for temporary relief of eye redness and itching caused by allergens. It is not intended to treat glaucoma or redness caused by an eye infection.
How to Save on Naphcon-A
Naphcon-A does not have a manufacturer copay or savings card program, since it's an OTC product available without a prescription. A generic version of this naphazoline/pheniramine combination is available, and prices can vary by pharmacy and by whether you buy the brand or the generic. Enter your ZIP above to compare today's price at pharmacies near you, and check whether an Rx.com coupon lowers the price further, since some OTC eye drops end up cheaper with a coupon at checkout than the shelf price.
Naphcon-A vs. Other Eye Allergy Drops
Naphcon-A shares its exact active-ingredient combination with Opcon-A and with Visine-A/Visine Allergy Eye Relief, so those products work the same way. Plain Visine redness reliever products that don't include an antihistamine won't relieve itching the way Naphcon-A does.
Other allergy eye drop options include antihistamine-only drops such as ketotifen and Zaditor, as well as Pataday, which is now also available over the counter. Unlike Naphcon-A, these do not rely on a vasoconstrictor, so they don't carry the same rebound-redness risk with extended use. Talk to your pharmacist or eye doctor about which option best fits your symptoms.
Safety Information
Naphcon-A is sold over the counter and does not carry a boxed warning. Remove contact lenses before applying the drops and wait at least 15 minutes before putting them back in. Don't use the solution if it changes color or becomes cloudy.
- Using the drops too often or for too long can cause rebound redness (rebound hyperemia) from the vasoconstrictor ingredient.
- Consult a doctor before use in children under 6.
- Stop use and see a doctor if you have eye pain, changes in vision, or if redness or irritation lasts or gets worse over 72 hours.
- If you have glaucoma, check with a physician before using this product because of the vasoconstrictor component.
- The most common side effects are burning/stinging and increased light sensitivity.
This is general information, not medical advice. Talk with your doctor or pharmacist about whether Naphcon-A is right for you.
This Naphcon-A information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Naphcon-A on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.
