Nebivolol Hcl
Nebivolol HCl 5MG
What is Nebivolol Hcl?
Nebivolol HCl (Bystolic) is a prescription beta blocker used to treat high blood pressure (hypertension). It helps lower blood pressure by slowing the heart rate and relaxing blood vessels, reducing the risk of heart attack, stroke, kidney disease, and other cardiovascular complications.
Side Effects
- Shortness of breath
- Rapid weight gain
- Swelling in your hands, ankles, or feet
Warnings
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have severe chest pain or have had a recent heart attack. Tell your doctor if you have kidney disease, liver disease, blood vessel disease, diabetes, an overactive thyroid, or an adrenal gland tumor called pheochromocytoma. Tell your doctor if you have poor blood flow to your legs and feet, or if you are scheduled for any surgery.
- Do not stop using this medicine suddenly without asking your doctor, or you could develop life-threatening heart problems. You may need to slowly decrease your dose before stopping it completely.
- This medicine may raise or lower your blood sugar level. If you have diabetes, report any changes in your blood sugar to your doctor.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- This medicine may make you dizzy or drowsy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
Prescription savings · · · ·
What is Nebivolol Hcl ?
Nebivolol HCl (Bystolic) is a prescription beta blocker used to treat high blood pressure (hypertension). It helps lower blood pressure by slowing the heart rate and relaxing blood vessels, reducing the risk of heart attack, stroke, kidney disease, and other cardiovascular complications.
- Shortness of breath
- Rapid weight gain
- Swelling in your hands, ankles, or feet
- Slow or uneven heartbeat
- Lightheadedness or fainting
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have severe chest pain or have had a recent heart attack. Tell your doctor if you have kidney disease, liver disease, blood vessel disease, diabetes, an overactive thyroid, or an adrenal gland tumor called pheochromocytoma. Tell your doctor if you have poor blood flow to your legs and feet, or if you are scheduled for any surgery.
- Do not stop using this medicine suddenly without asking your doctor, or you could develop life-threatening heart problems. You may need to slowly decrease your dose before stopping it completely.
- This medicine may raise or lower your blood sugar level. If you have diabetes, report any changes in your blood sugar to your doctor.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- This medicine may make you dizzy or drowsy. Do not drive, use machines, or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Even if you feel well, do not stop using this medicine without asking your doctor. This medicine will not cure your high blood pressure, but it will help lower it and keep it down. You may have to take blood pressure medicine for the rest of your life.
Nebivolol Hcl Coupons & Prices
Nebivolol HCl 5MG
4 ED medications in one dose
Sildenafil, tadalafil, PT-141 & L-Citrulline · Works in ~15 min · Lasts up to 36 hours
Looking for a nebivolol HCl coupon? Nebivolol (the generic form of Bystolic) is a prescription beta-blocker used to treat high blood pressure. As a generic, it is already an affordable option, but the cash price can vary widely from one pharmacy to the next, so it pays to compare. Enter your ZIP above to see today's price and pull a free Rx.com discount coupon accepted at more than 60,000 U.S. pharmacies.
What is nebivolol and how does it work?
Nebivolol (nebivolol hydrochloride) is a cardioselective beta-blocker, meaning it mainly acts on the beta-1 receptors in the heart. It is FDA-approved to treat hypertension (high blood pressure) in adults, either on its own or combined with other blood-pressure medicines. By slowing the heart rate and easing the heart's workload, it helps lower blood pressure. Nebivolol is a bit different from older beta-blockers because it also promotes nitric-oxide-mediated relaxation of the blood vessels, which helps them widen.
Nebivolol is the same active ingredient found in the brand-name drug Bystolic. It is sometimes prescribed off-label for other heart conditions, but high blood pressure is its only FDA-approved use. Always take it exactly as your provider directs.
Nebivolol cost and savings without insurance
Because nebivolol is available as an FDA-approved generic, it is generally one of the lower-cost beta-blockers, even if you are paying cash. The catch is that pharmacies set their own cash prices, so what you pay can differ significantly depending on where you fill the prescription. Comparing prices before you go is the single best way to keep your cost down.
Enter your ZIP code above to see today's nebivolol price at pharmacies near you and to pull a free Rx.com discount coupon. Our tool compares prices across more than 60,000 pharmacies so you can find the best local deal. If your provider prescribes brand-name Bystolic, the manufacturer also offers a copay savings program on its official website (Bystolic.com); eligibility and terms vary, and manufacturer copay cards typically cannot be combined with a discount coupon.
Nebivolol vs. other beta-blockers
Nebivolol is one of several beta-blockers used for blood pressure and heart conditions. The best choice depends on your health history, other medications, and how you respond, which is a conversation to have with your provider. Other commonly prescribed beta-blockers include:
- Metoprolol — a widely used beta-1 selective beta-blocker for blood pressure and heart conditions
- Carvedilol — a combined alpha/beta-blocker often used in heart failure
- Atenolol — a long-established beta-1 selective option
- Bisoprolol — another beta-1 selective beta-blocker
Nebivolol's nitric-oxide-related vessel widening sets it apart from these older options. Compare prices for each on Rx.com to see what fits your budget, and let your prescriber guide the medical choice.
Safety, side effects, and important warnings
Nebivolol does not carry an FDA boxed warning, but there are important safety points to know. Do not stop taking it suddenly. Stopping abruptly can cause serious problems, including worsening chest pain (angina), heart attack, or dangerous heart rhythms. If you and your provider decide to stop, the dose is usually tapered gradually over one to two weeks. The most common side effects are headache, fatigue, dizziness, and swelling in the legs or feet (peripheral edema). Nebivolol can also slow the heart rate too much (bradycardia) or lower blood pressure.
Tell your provider if you have asthma or COPD, diabetes (nebivolol may mask signs of low blood sugar), or an overactive thyroid (it may hide a fast heartbeat). It should not be used in people with very slow heart rate, certain heart-block conditions, cardiogenic shock, decompensated heart failure, sick sinus syndrome without a pacemaker, or severe liver problems. This information is not medical advice. Talk with your doctor or pharmacist about your full health history and any other medicines you take.
This Nebivolol Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Nebivolol Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Browse more medications: starting with N · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.