What is Nivestym ?

Nivestym (filgrastim-aafi) is a recombinant human granulocyte colony-stimulating factor (G-CSF) analog approved by the FDA. It is used to stimulate the production of white blood cells, thereby helping to decrease the risk of infection in patients undergoing myelosuppressive chemotherapy, those with acute myeloid leukemia receiving induction or consolidation chemotherapy, and in patients with severe chronic neutropenia. Nivestym is a biosimilar to Neupogen.

• Decrease in how much or how often you urinate, red or dark brown urine, lower back or side pain
• Unusual bleeding, bruising, tiredness, or weakness
• Pain in your left side or shoulder, feeling unusually full
• Trouble breathing or fast breathing
• Swelling in your face, ankles, or feet
• Lightheadedness, dizziness, fainting
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Coughing up blood
• Fever, chills, cough, sore throat, body aches, stomach pain
• Skin redness, blisters, or sores, red or purple spots on your skin

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, lung disease, breathing problems, or sickle cell disease. Tell your doctor if you have an allergy to latex.
• This medicine may cause the following problems:Spleen problemsSerious lung problems (including acute respiratory distress syndrome)Kidney problemsCapillary leak syndromeBlood or bone marrow problems (including myelodysplastic syndrome or acute myeloid leukemia) in patients with breast or lung cancerCutaneous vasculitis (inflammation of blood vessels in the skin)Aortitis (inflammation of the largest artery in the body)
• This medicine lowers the number of certain blood cells, so you may bleed or bruise more easily. Be careful to avoid injuries.
• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.
• Skin redness, blisters, or sores, red or purple spots on your skin
• Swelling in your face, ankles, or feet
• Trouble breathing or fast breathing
• Unusual bleeding, bruising, tiredness, or weakness