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Norethindrone Acetate Tablet — prescription drug image

Norethindrone Acetate

Norethindrone Acetate 5MG

Women's Health Care
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What is Norethindrone Acetate?

Aygestin is a prescription medication used to treat women diagnosed with endometriosis. Norethindrone is the generic version of Aygestin. Aygestin costs around $112 for a supply of 20, 5 mg tablets, but luckily there are ways to save money. You can use our Rx.com savings offer to get an Aygestin discount of up to 80% off of the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Norethindrone Acetate ?

Aygestin is a prescription medication used to treat women diagnosed with endometriosis. Norethindrone is the generic version of Aygestin. Aygestin costs around $112 for a supply of 20, 5 mg tablets, but luckily there are ways to save money. You can use our Rx.com savings offer to get an Aygestin discount of up to 80% off of the retail price at participating pharmacies near you.
  • Unusual vaginal bleeding, spotting, discharge, or itching
  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Trouble seeing, double vision, or other eye problems
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Breast tenderness or swelling
  • Chest pain, trouble breathing, coughing up blood
  • Dark urine or pale stools, loss of appetite, nausea, vomiting, stomach pain, yellow skin or eyes
  • Irregular, late, or missed menstrual period
  • Severe headache, sensitivity to light or sound
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor right away if you think you have become pregnant. If you miss two periods in a row, call your doctor for a pregnancy test before you take any more pills.
  • Tell your doctor if you are breastfeeding or if you have kidney disease, lupus, high blood pressure, high cholesterol, seizures, asthma, migraine headaches, diabetes, or a history of depression. Tell your doctor if you smoke.
  • This medicine may cause the following problems:Increased risk of ectopic pregnancy (pregnancy outside the uterus)Cysts in the ovariesIrregular menstrual bleedingIncreased risk of breast cancerLiver problems, including liver cancer or tumorIncreased risk of blood clots, heart attack, or stroke
  • This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
  • Use a second form of birth control during the first 3 weeks to make sure you are protected from pregnancy.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is norethindrone acetate used for?
It's FDA-approved to treat endometriosis, secondary amenorrhea, and abnormal uterine bleeding caused by hormonal imbalance when no other cause is found.
Is Aygestin still available?
The Aygestin brand name has been discontinued in the U.S. Norethindrone acetate is still available and prescribed as an FDA-approved generic tablet.
What are the risks of norethindrone acetate?
Progestins like norethindrone acetate can increase the risk of blood clots, stroke, and heart attack, so it's not recommended for people with a history of these conditions or certain other risk factors. Talk to your provider about your personal risk.
Can norethindrone acetate be used as birth control?
Norethindrone acetate tablets are labeled for endometriosis and menstrual conditions rather than as a standalone contraceptive; ask your provider which progestin product fits your needs.
How can I save on norethindrone acetate?
Since it's a generic with prices that vary by pharmacy, comparing cash prices or using a coupon can lower your cost. Enter your ZIP code above to see current prices near you.
How much does Norethindrone Acetate cost without insurance?
The price of Norethindrone Acetate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 75% off retail prices with a free Rx.com coupon.
What are the common side effects of Norethindrone Acetate?
Common side effects of Norethindrone Acetate may include: Unusual vaginal bleeding, spotting, discharge, or itching, Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking, Trouble seeing, double vision, or other eye problems, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Breast tenderness or swelling. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Norethindrone Acetate?
Generic versions may be available for Norethindrone Acetate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Norethindrone Acetate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Norethindrone Acetate?
The cheapest pharmacy for Norethindrone Acetate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Norethindrone Acetate near you.

Norethindrone Acetate Coupons & Prices

Norethindrone Acetate 5MG

Women's Health Care
Licensed US providers · Online visit in minutes
Norethindrone Acetate Tablet — prescription drug image
Prescription
Norethindrone Acetate 5mg (10)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Norethindrone acetate is a progestin tablet prescribed for endometriosis, irregular menstrual bleeding, and secondary amenorrhea. The brand name Aygestin is no longer marketed in the U.S., so a norethindrone acetate coupon can help lower the cost of the generic tablet, since cash prices vary by pharmacy. Enter your ZIP above to see today's price near you.

What Is Norethindrone Acetate and How Does It Work?

Norethindrone acetate is a synthetic progestin taken as a tablet. It's FDA-labeled to treat endometriosis, secondary amenorrhea (absent periods not caused by pregnancy), and abnormal uterine bleeding due to hormonal imbalance when no organic cause is found. It works by supplying a progestin hormone that helps regulate the uterine lining.

Comparing Norethindrone Acetate Prices

Norethindrone acetate is only available as a generic tablet in the U.S.; the original brand, Aygestin, has been discontinued. Because it's a generic, cash prices can vary widely between pharmacies. Rx.com compares prices at more than 60,000 U.S. pharmacies so you can find a lower price or use a free coupon, whether or not you have insurance.

  • Prices differ by pharmacy, strength, and quantity
  • A coupon can help if you're uninsured or your copay is high
  • Ask your pharmacist to check nearby locations if one is out of stock

Norethindrone Acetate vs. Other Progestins

Norethindrone acetate is one of several progestin options prescribed for menstrual and reproductive conditions; medroxyprogesterone acetate is another commonly used progestin tablet. Your provider chooses based on your specific condition, medical history, and any other medications you take.

Safety Information

Norethindrone acetate can increase the risk of blood clots, including deep vein thrombosis, pulmonary embolism, stroke, and heart attack, and it's contraindicated in people with a history of these conditions, active or recent arterial thromboembolic disease, known or suspected pregnancy, undiagnosed vaginal bleeding, or a history of breast cancer. This is general information, not medical advice — talk to your provider about whether norethindrone acetate is right for you.

Sources & accuracy

This Norethindrone Acetate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Norethindrone Acetate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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