Perforomist
Perforomist 2ML of 20MCG/2ML
What is Perforomist?
Perforomist is use to prevent asthma attacks, and it is also used to treat other lung conditions. There is not a generic version of Perforomist currently available. The average Perforomist cash price can be expensive at about $576 for a supply of 60, 2 mL vials of 20 mcg/2 mL inhalation solution. You can lower your Perforomist cost by up to 80% by using our free Perforomist savings card at a pharmacy near you that participates with Rx.com.Side Effects
- Worsening of breathing problems
- Seizures or tremors
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- This medicine may cause the following problems:Increased risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take Perforomist® without an inhaled steroidParadoxical bronchospasm (trouble breathing right after use), which can be life-threateningHigh blood pressureHeart rhythm problemsHigh blood sugar levels
- This should not be the first and only medicine you use for asthma or COPD. This medicine will not stop an asthma or COPD attack that has already started. Your doctor may prescribe another medicine for an acute asthma attack or an acute COPD flare-up. If the other medicine does not work as well, tell your doctor right away.
- The powder in the capsule contains trace amounts of milk proteins. Make sure your doctor knows if you have a severe milk protein allergy.
- Inhalation routeIf any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
- Inhalation routeIf you use a corticosteroid medicine to control your asthma, keep using it as instructed by your doctor.
Prescription savings · · · ·
What is Perforomist ?
Perforomist is use to prevent asthma attacks, and it is also used to treat other lung conditions. There is not a generic version of Perforomist currently available. The average Perforomist cash price can be expensive at about $576 for a supply of 60, 2 mL vials of 20 mcg/2 mL inhalation solution. You can lower your Perforomist cost by up to 80% by using our free Perforomist savings card at a pharmacy near you that participates with Rx.com.- Worsening of breathing problems
- Seizures or tremors
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Increased hunger, thirst, or urination, weight loss
- Lightheadedness, dizziness, fainting
- Dry mouth, muscle cramps, nausea, vomiting
- Increased trouble breathing
- Chest pain, fast, pounding, or uneven heartbeat
- This medicine may cause the following problems:Increased risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take Perforomist® without an inhaled steroidParadoxical bronchospasm (trouble breathing right after use), which can be life-threateningHigh blood pressureHeart rhythm problemsHigh blood sugar levels
- This should not be the first and only medicine you use for asthma or COPD. This medicine will not stop an asthma or COPD attack that has already started. Your doctor may prescribe another medicine for an acute asthma attack or an acute COPD flare-up. If the other medicine does not work as well, tell your doctor right away.
- The powder in the capsule contains trace amounts of milk proteins. Make sure your doctor knows if you have a severe milk protein allergy.
- Inhalation routeIf any of your asthma medicines do not seem to be working as well as usual, call your doctor right away. Do not change your doses or stop using your medicines without asking your doctor.
- Inhalation routeIf you use a corticosteroid medicine to control your asthma, keep using it as instructed by your doctor.
- Call your doctor if your symptoms do not improve or if they get worse.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Tell your doctor if you are pregnant or breastfeeding, or if you have heart or blood vessel disease (including aneurysm), heart rhythm problems, high blood pressure, angina (severe chest pain), adrenal gland problem (including pheochromocytoma), diabetes, epilepsy or seizures, electrolyte imbalance, or thyroid problems.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Perforomist Coupons & Prices
Perforomist 2ML of 20MCG/2ML
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Looking for a Perforomist coupon? Perforomist (formoterol fumarate inhalation solution) is a long-acting bronchodilator that is nebulized twice a day to help keep the airways open in adults with COPD. It can be expensive at the pharmacy counter, especially if you are paying cash or your plan does not cover it. Rx.com offers a free cash discount coupon you can use at most major pharmacies, and there is now an FDA-approved generic formoterol fumarate inhalation solution as well. Prices vary from pharmacy to pharmacy and between the brand and the generic, so it is worth comparing. Enter your ZIP code above to see today's price for Perforomist and the generic near you, then show the coupon at the pharmacy.
What is Perforomist and how does it work?
Perforomist is the brand name for formoterol fumarate inhalation solution, a long-acting beta2-adrenergic agonist (LABA) bronchodilator. It relaxes the muscles that tighten around the airways, which makes breathing easier. It is FDA-approved for long-term, twice-daily maintenance treatment of bronchoconstriction in adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Perforomist comes as a 20 mcg/2 mL unit-dose vial that you breathe in through a jet nebulizer connected to an air compressor. The usual dose is one vial in the morning and one in the evening, with a maximum of 40 mcg per day. Because it is a nebulized liquid rather than a handheld inhaler, it is often used by people who have trouble with the timing and breath coordination that handheld inhalers require. Do not mix Perforomist with other medicines in the nebulizer cup. Formoterol is also an ingredient in several combination metered-dose inhalers sold under other brand names, but those are different products and are not direct substitutes for Perforomist.
Perforomist cost: manufacturer savings card vs. Rx.com cash coupon
The manufacturer of Perforomist runs an official savings card program. Like most brand savings cards, it is limited to people with commercial (private) insurance, and it cannot be used if you have Medicare, Medicaid, TRICARE, or other government coverage. Eligibility rules, expiration dates, benefit limits, and the enrollment page itself change from time to time, so ask your prescriber or pharmacist for the current program details and read the terms before you count on it. If you are uninsured, on Medicare, or the card is declined at the counter, the manufacturer card will not help you.
That is where the Rx.com cash coupon comes in. It is free, requires no insurance, and works as a cash-price discount at most major pharmacies, including for people on Medicare who would otherwise be shut out of the manufacturer program. You cannot combine a discount coupon with insurance on the same fill, but you can compare: run the cash price with the Rx.com coupon against your copay and pay whichever is lower. Enter your ZIP above to see today's price at pharmacies near you. It is also worth asking your prescriber or pharmacist whether the manufacturer offers a patient assistance program if cost is a barrier, since some brand manufacturers provide medicine at low or no cost to patients who qualify.
Ask about the generic formoterol fumarate inhalation solution
An FDA-approved generic formoterol fumarate inhalation solution is now marketed in the United States. It contains the same active ingredient in the same 20 mcg/2 mL unit-dose nebulizer vial and is substitutable for the brand, so most pharmacies can fill it in place of Perforomist unless your prescriber writes "dispense as written."
Ask your prescriber to write the prescription for formoterol fumarate inhalation solution, or ask your pharmacist whether the generic is in stock. Prices for both the brand and the generic differ from pharmacy to pharmacy, even in the same town, so compare both with your ZIP code above. An Rx.com coupon can be applied to the generic as well as the brand.
Perforomist alternatives and how they compare
Perforomist is a maintenance medicine, not a rescue treatment. It will not relieve a sudden attack of breathlessness. For sudden symptoms, a short-acting bronchodilator such as albuterol is what your doctor will prescribe. Keep your rescue medicine with you even while using Perforomist.
Other maintenance options your prescriber might consider, depending on your diagnosis and how well your COPD is controlled:
- Brovana (arformoterol) is the other nebulized long-acting beta2-agonist, dosed twice daily, and is the closest alternative in the same delivery form.
- Spiriva (tiotropium) is a long-acting anticholinergic inhaler, a different class of maintenance bronchodilator for COPD.
- Symbicort is a combination metered-dose inhaler containing formoterol plus an inhaled corticosteroid, rather than a nebulizer solution.
These are not interchangeable with one another. Only your prescriber can decide which combination is right for you; do not switch or stop a maintenance medicine on your own.
Safety, side effects, and who should not use Perforomist
Perforomist's current FDA labeling does not carry a boxed warning (the older LABA asthma-death boxed warning was removed from the label in 2019), but the underlying class risk has not gone away. The label's contraindication is specific: use of a LABA, including Perforomist, without an inhaled corticosteroid is contraindicated in patients with asthma. Perforomist is not indicated for the treatment of asthma at all. Perforomist is also not a rescue medicine: do not use it for sudden symptoms or for COPD that is getting worse quickly, since that can be life-threatening. Do not exceed the prescribed dose or use it with another LABA, because excessive use of inhaled sympathomimetics has been linked to serious heart effects and fatalities.
Tell your doctor if you have heart disease (especially coronary insufficiency, an irregular heartbeat, or high blood pressure), seizures, thyroid problems, or diabetes, since Perforomist can raise heart rate and blood pressure, prolong the QTc interval, lower potassium, and raise blood sugar. Rarely, it can cause paradoxical bronchospasm (breathing that suddenly gets worse right after a dose) or an allergic reaction such as rash, swelling, or anaphylaxis; stop the medicine and seek care immediately if that happens. In the 12-week clinical trial, the adverse reactions reported in at least 2% of people taking Perforomist and more often than with placebo were diarrhea, nausea, nasopharyngitis (cold-like symptoms), dry mouth, vomiting, dizziness, and insomnia. Separately, as a beta2-agonist, Perforomist can produce class effects such as tremor, nervousness, palpitations, muscle cramps, and a faster heart rate; get medical help right away if you develop chest pain or a pounding or irregular heartbeat. Review your other medicines with your pharmacist, particularly MAO inhibitors, tricyclic antidepressants, other QT-prolonging drugs, beta-blockers (which can block the bronchodilator effect), and certain diuretics. This page is information, not medical advice; talk with your healthcare provider about what is right for you.
This Perforomist information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Perforomist on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.