Petrolatum
Petrolatum 454GM of 42%
What is Petrolatum?
Petrolatum is a topical ointment primarily used to moisturize and protect dry skin. It acts as a barrier, preventing moisture loss while soothing minor skin irritations. Commonly found in skincare products, petrolatum is easily accessible for prescription online. Discover its benefits at Rx.com, where you can compare costs and access savings cards for your prescriptions.Side Effects
- Rarely, skin irritation
- Possibly pore clogging if used extensively on the face, especially in acne-prone areas
Warnings
- Avoid using on deep or puncture wounds, animal bites, or serious burns without medical advice
- If condition worsens or does not improve within 7 days, consult a doctor
Prescription savings · · · ·
What is Petrolatum ?
Petrolatum is a topical ointment primarily used to moisturize and protect dry skin. It acts as a barrier, preventing moisture loss while soothing minor skin irritations. Commonly found in skincare products, petrolatum is easily accessible for prescription online. Discover its benefits at Rx.com, where you can compare costs and access savings cards for your prescriptions.- Rarely, skin irritation
- Possibly pore clogging if used extensively on the face, especially in acne-prone areas
- Avoid using on deep or puncture wounds, animal bites, or serious burns without medical advice
- If condition worsens or does not improve within 7 days, consult a doctor
Petrolatum Coupons & Prices
Petrolatum 454GM of 42%
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Petrolatum prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 100gm of 42% · Jar | 100 | $11.99 | $9.76 |
| 454gm of 42% · Jar | 454 | $36.13 | $16.65 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Petrolatum (also sold as white petrolatum, or under brand names like Vaseline) is an over-the-counter skin protectant found in ointments, lip balms, and diaper-rash products. It doesn't require a prescription, but if your doctor has you using a prescription-strength petrolatum-based ointment or a related skin product, enter your ZIP above to see today's price and find a petrolatum coupon at pharmacies near you.
What is petrolatum and how does it work?
Petrolatum is a soft, semi-solid mixture of hydrocarbons refined for medical use. It doesn't absorb into the skin or treat any underlying condition; instead it sits on the surface and forms an occlusive barrier that seals in moisture and shields skin from air, wind, and friction. Under the FDA's over-the-counter skin protectant rules, petrolatum is recognized as safe and effective for temporarily protecting minor cuts, scrapes, and burns, and for temporarily protecting and helping relieve chapped or cracked skin and lips.
Saving on petrolatum products
Plain petrolatum is inexpensive and widely available without a prescription at any drug store, grocery store, or big-box retailer, usually store-brand and name-brand versions side by side. Prices vary by retailer and package size, so it's worth comparing before you buy. If your provider has prescribed a medicated ointment that contains petrolatum as a base, or a specialty skin-barrier product, you can enter your ZIP above to compare pharmacy prices and see whether a coupon lowers the cost.
Petrolatum vs. other skin protectants
- Petrolatum — pure occlusive barrier, fragrance-free options widely available.
- Aquaphor — contains petrolatum along with additional ingredients such as lanolin alcohol and glycerin.
- Dimethicone or zinc-oxide based protectants — often used in diaper-rash and barrier creams as alternative occlusive or protective agents.
All of these work by physically protecting the skin rather than by any drug action, so the right choice usually comes down to texture preference, added ingredients, and where on the body you're using it.
Safety information
Petrolatum is for external use only. Stop use and ask a doctor if the condition worsens, if symptoms last more than seven days, or if a rash or irritation develops. Avoid use in the eyes, and check with a doctor before applying to deep or puncture wounds, animal bites, or serious burns. This is general information, not medical advice — talk to your doctor or pharmacist about the right product for your skin concern.
This Petrolatum information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Petrolatum on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.